Results 41 to 50 of about 3,888,779 (212)
The EVcouplings Python framework for coevolutionary sequence analysis
bioRxiv, 2018 Summary Coevolutionary sequence analysis has become a commonly used technique for de novo prediction of the structure and function of proteins, RNA, and protein complexes.
Thomas A. Hopf +15 more
semanticscholar +1 more source
Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases
Cell Reports, 2021 Summary: Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively little
David Bradley +5 more
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Protein Sequence Retrieval and Phylogenetic Analysis of Various α-amylase Producing Bacillus species [PDF]
International Journal Bioautomation, 2020 Due to advancements made in biotechnology, genetic manipulation and medium optimization has been possible and that has led to high yield in enzyme especially α-amylase with improvised properties that find its application suitably in detergent, laundry ...
Sonali Priyadarshini +2 more
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Journal of Information and TelecommunicationUnderstanding protein-protein interactions (PPIs) is essential because knowledge regarding PPIs helps in determining the biochemical functions of organisms. Advances made in machine learning techniques, for example, DeepFE-PPI, GcForest-PPI, and DeepPPI,
Tran Hoai Nhan +2 more
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Comprehensive analysis of sequences of a protein switch [PDF]
Protein Science, 2015 AbstractSwitches form a special class of proteins that dramatically change their three‐dimensional structures upon a small perturbation. One possible perturbation that we explore is that of a single point mutation. Building on the pioneering experimental work of Alexander et al. (Alexander et al.
Ron Elber, Szu Hua Chen, Jaroslaw Meller
openaire +3 more sources
Spectral Analysis of Sequence Variability in Basic-Helix-loop-helix (bHLH) Protein Domains
Evolutionary Bioinformatics, 2006 The basic helix-loop-helix (bHLH) family of transcription factors is used as a paradigm to explore structural implications of periodicity patterns in amino acid sequence variability.
Zhi Wang, William R. Atchley
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DispHScan: A Multi-Sequence Web Tool for Predicting Protein Disorder as a Function of pH
Biomolecules, 2021 Proteins are exposed to fluctuating environmental conditions in their cellular context and during their biotechnological production. Disordered regions are susceptible to these fluctuations and may experience solvent-dependent conformational switches ...
Carlos Pintado-Grima +4 more
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Nucleic Acids Res., 2016 The MPI Bioinformatics Toolkit (http://toolkit.tuebingen.mpg.de) is an open, interactive web service for comprehensive and collaborative protein bioinformatic analysis.
V. Alva +3 more
semanticscholar +1 more source
Comparison study on k-word statistical measures for protein: From sequence to 'sequence space'
BMC Bioinformatics, 2008 Background Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the same idea of using k-word frequencies of protein sequences.
Wang Tianming, Dai Qi
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Genetic Diversity and Prevalence of Porcine Circovirus Type 2 in China During 2000-2019
Frontiers in Veterinary Science, 2021 As the major pathogen for porcine circovirus-associated disease (PCVAD), porcine circovirus type 2 (PCV2) is no longer treated as an emerging virus anymore.
Ning Li +5 more
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