A Robust and Precise ConvNet for Small Non-Coding RNA Classification (RPC-snRC)
IEEE Access, 2021 Small non-coding RNAs (ncRNAs) are attracting increasing attention as they are now considered potentially valuable resources in the development of new drugs intended to cure several human diseases.
Muhammad Nabeel Asim +5 more
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Identification and sequence determination of a novel double-stranded RNA mycovirus from the entopathogenic fungus Beauveria bassina [PDF]
, 2015 The final publication is available at Springer via https://doi.org/10.1007/s00705-014-2332-8.An isolate of the entomopathogenic fungus Beauveria bassiana was found to contain five double-stranded (ds) RNA elements ranging from 1.5 to more than 3 kbp. The
Coutts, Robert H.A. +2 more
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Discovery and Analysis of RNA Viruses in Insects [PDF]
, 2022 Viruses are the most abundant pathogens on Earth infecting all cellular life forms. Only in recent years have we started to gain knowledge on insect viromes, thanks to the development of sequencing technologies.
Jurvansuu, Jaana, Viljakainen, Lumi
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RNA cytosine methylation analysis by bisulfite sequencing [PDF]
Nucleic Acids Research, 2008 Covalent modifications of nucleic acids play an important role in regulating their functions. Among these modifications, (cytosine-5) DNA methylation is best known for its role in the epigenetic regulation of gene expression. Post-transcriptional RNA modification is a characteristic feature of noncoding RNAs, and has been described for rRNAs, tRNAs and
Tim Pollex +3 more
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Stem-loop formation drives RNA folding in mechanical unzipping experiments [PDF]
PNAS 119 (3), 2022, 2022 Accurate knowledge of RNA hybridization is essential for understanding RNA structure and function. Here we mechanically unzip and rezip a 2-kbp RNA hairpin and derive the 10 nearest-neighbor base pair (NNBP) RNA free energies in sodium and magnesium with 0.1 kcal/mol precision using optical tweezers. Notably, force-distance curves (FDCs) exhibit strong
arxiv +1 more source
Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung [PDF]
, 1990 The complete amino acid sequence of the receptor for organic calcium channel blockers (CaCB) from rabbit lung has been deduced by cloning and sequence analysis of the cDNA.
Bean +24 more
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ANALYSIS OF LARGE-SCALE SEQUENCING OF SMALL RNAS [PDF]
Biocomputing 2008, 2007 The advent of large-scale sequencing has opened up new areas of research, such as the study of Piwi-interacting small RNAs (piRNAs). piRNAs are longer than miRNAs, close to 30 nucleotides in length, involved in various functions, such as the suppression of transposons in germline. Since a large number of them (many tens of thousands) are generated from
Olson, A. J. +4 more
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TT2NE: A novel algorithm to predict RNA secondary structures with pseudoknots [PDF]
, 2010 We present TT2NE, a new algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus.
Bailor +29 more
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RNA Sequencing Data: Hitchhiker's Guide to Expression Analysis [PDF]
Annual Review of Biomedical Data Science, 2018 Gene expression is the fundamental level at which the results of various genetic and regulatory programs are observable. The measurement of transcriptome-wide gene expression has convincingly switched from microarrays to sequencing in a matter of years.
Mark D. Robinson +8 more
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Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
BMC Bioinformatics, 2010 Background In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two decades ago for proteins, which gave the fundamental grounds for developing ...
Capriotti Emidio, Marti-Renom Marc A
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