Results 11 to 20 of about 2,556,924 (316)

Analyzing integrated network of methylation and gene expression profiles in lung squamous cell carcinoma

open access: yesScientific Reports, 2022
Gene expression, DNA methylation, and their organizational relationships are commonly altered in lung squamous cell carcinoma (LUSC). To elucidate these complex interactions, we reconstructed a differentially expressed gene network and a differentially ...
Yusri Dwi Heryanto   +2 more
doaj   +1 more source

A domain sequence approach to pangenomics: applications to Escherichia coli [v2; ref status: indexed, http://f1000r.es/ul]

open access: yesF1000Research, 2013
The study of microbial pangenomes relies on the computation of gene families, i.e. the clustering of coding sequences into groups of essentially similar genes. There is no standard approach to obtain such gene families.
Lars-Gustav Snipen, David W Ussery
doaj   +1 more source

SCCmecFinder, a Web-Based Tool for Typing of Staphylococcal Cassette Chromosome mec in Staphylococcus aureus Using Whole-Genome Sequence Data

open access: yesmSphere, 2018
Typing of methicillin-resistant Staphylococcus aureus (MRSA) is important in infection control and surveillance. The current nomenclature of MRSA includes the genetic background of the S.
Hülya Kaya   +9 more
doaj   +1 more source

Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells

open access: yesStem Cell Research, 2014
The shortage of molecular information on cell cycle changes along embryonic stem cell (ESC) differentiation prompts an in silico approach, which may provide a novel way to identify candidate genes or mechanisms acting in coordinating the two programs. We
Angela Re   +4 more
doaj   +1 more source

Is the pan-genome also a pan-selectome? [v1; ref status: indexed, http://f1000r.es/Vl9wKI]

open access: yesF1000Research, 2012
The comparative genomics of prokaryotes has shown the presence of conserved regions containing highly similar genes (the 'core genome') and other regions that vary in gene content (the ‘flexible’ regions).
Francisco Rodriguez-Valera   +1 more
doaj   +1 more source

Crime Script Sequencing: An optimal forensic combination for cold case analysis

open access: yesForensic Science International: Synergy, 2022
Criminal cases go cold when investigative leads or forensic testing does not lead to a successful arrest. In these cases, investigators are often keen to use novel methods to derive fresh ideas or insights.
D.A. Keatley, M. Arntfield, D.D. Clarke
doaj  

ANALYZING THE GENOMIC VARIATION OF MICROBIAL CELL FACTORIES IN THE ERA OF “NEW BIOTECHNOLOGY”

open access: yesComputational and Structural Biotechnology Journal, 2012
The application of genome-scale technologies, both experimental and in silico, to industrial biotechnology has allowed improving the conversion of biomass-derived feedstocks to chemicals, materials and fuels through microbial fermentation. In particular,
Markus Herrgård, Gianni Panagiotou
doaj   +1 more source

Dissecting spatio‐temporal protein networks driving human heart development and related disorders

open access: yesMolecular Systems Biology, 2010
Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the underlying processes is very limited. Using heart morphogenesis as general model for dissecting
Kasper Lage   +20 more
doaj   +1 more source

Asymptotic Analysis of Regular Sequences [PDF]

open access: yesAlgorithmica, 2019
Abstract In this article, q-regular sequences in the sense of Allouche and Shallit are analysed asymptotically. It is shown that the summatory function of a regular sequence can asymptotically be decomposed as a finite sum of periodic fluctuations multiplied by a scaling factor. Each of these terms corresponds to an eigenvalue of the sum of matrices of
Clemens Heuberger, Daniel Krenn
openaire   +4 more sources

Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids

open access: yesBio-Protocol, 2020
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo   +8 more
doaj   +1 more source

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