Results 81 to 90 of about 29,786,749 (389)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Genome-wide identification and expression of TIFY family in cassava (Manihot esculenta Crantz)

Frontiers in Plant Science, 2022
Plant-specific TIFY [TIF(F/Y)XG] proteins serve important roles in the regulation of plant stress responses. This family encodes four subfamilies of proteins, JAZ (JASMONATE ZIM-domain), PPD (PEAPOD), ZML (Zinc-finger Inflorescence-like), and TIFY.
Linling Zheng, Qi Wan, Honggang Wang, Honggang Wang, Changlin Guo, Changlin Guo, Xiaolei Niu, Xiaolei Niu, Xiaofei Zhang, Rui Zhang, Rui Zhang, Yinhua Chen, Yinhua Chen, Kai Luo, Kai Luo   +14 more
doaj   +1 more source

W(h)ither Fossils? Studying Morphological Character Evolution in the Age of Molecular Sequences [PDF]

, 2008
A major challenge in the post-genomics era will be to integrate molecular sequence data from extant organisms with morphological data from fossil and extant taxa into a single, coherent picture of phylogenetic relationships; only then will these ...
Bull J. J., Cuevas J., Desutter-Grandcolas L., Eernisse D. J., Elizabeth J. Hermsen, Giribet G., Grande L., Hedges S. B., Hermsen E. J., Horovitz I., Horovitz I., Jonathan R. Hendricks, Luckow M., Montgelard C., Norell M. A., Novacek M. J., O'Leary M., Rowe T., Simmons N. B., Wiens J. J., Xiang Q-Y. J., Zhang J.   +21 more
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Analysis of DNA sequence variation within marine species using Beta-coalescents [PDF]

, 2011
We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme
Birkner, Matthias, Blath, Jochen, Steinrücken, Matthias   +2 more
core   +3 more sources

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations

Leukemia, 2017
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia : updated ERIC ...
Richard Rosenquist, Richard Rosenquist, P. Ghia, A. Hadzidimitriou, L. Sutton, L. Sutton, A. Agathangelidis, P. Baliakas, N. Darzentas, V. Giudicelli, M. Lefranc, A. Langerak, C. Belessi, Frédéric Davi, K. Stamatopoulos   +14 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Patterns of Healthy Aging and Household Size Dynamics in Western Europe

Monitoring Obŝestvennogo Mneniâ: Ekonomičeskie i Socialʹnye Peremeny, 2020
The diversity of family structures and the quality of social relationships are closely tied to one another. Individual characteristics such as parenting, grandparenting, partnership, cohabitation, living apart together, living solo and other contextual ...
Валентина Ивановна Шиповская
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Sequencing Analysis Guide

, 2020
Sanger sequencing is a method of DNA sequencing that is based on the selective incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication. Sanger sequencing analysis software packages are used for base calling (process of assigning nucleobases to chromatogram peaks), sequence alignment, trace visualization ...
Michael Nicouleau, Thomas M. Durcan
openaire   +2 more sources