Results 81 to 90 of about 31,098,092 (376)

The SH2 Domain Interaction Landscape

Cell Reports, 2013
Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.
Michele Tinti, Lars Kiemer, Stefano Costa, Martin L. Miller, Francesca Sacco, Jesper V. Olsen, Martina Carducci, Serena Paoluzi, Francesca Langone, Christopher T. Workman, Nikolaj Blom, Kazuya Machida, Christopher M. Thompson, Mike Schutkowski, Søren Brunak, Matthias Mann, Bruce J. Mayer, Luisa Castagnoli, Gianni Cesareni   +18 more
doaj   +1 more source

Genome-Guided Analysis of Seven Weed Species Reveals Conserved Sequence and Structural Features of Key Gene Targets for Herbicide Development

Frontiers in Plant Science, 2022
Herbicides are commonly deployed as the front-line treatment to control infestations of weeds in native ecosystems and among crop plants in agriculture. However, the prevalence of herbicide resistance in many species is a major global challenge.
Sarah Shah, Sarah Shah, Thierry Lonhienne, Cody-Ellen Murray, Yibi Chen, Yibi Chen, Katherine E. Dougan, Katherine E. Dougan, Yu Shang Low, Craig M. Williams, Gerhard Schenk, Gerhard Schenk, Gerhard Schenk, Gimme H. Walter, Luke W. Guddat, Cheong Xin Chan, Cheong Xin Chan   +16 more
doaj   +1 more source

Fast Sequence Component Analysis for Attack Detection in Synchrophasor Networks [PDF]

, 2015
Modern power systems have begun integrating synchrophasor technologies into part of daily operations. Given the amount of solutions offered and the maturity rate of application development it is not a matter of "if" but a matter of "when" in regards to ...
Barella, Richard, Bass, Robert B., Cotilla-Sanchez, Eduardo, Landford, Jordan, Meier, Rich, Wallace, Scott, Zhao, Xinghui   +6 more
core   +2 more sources

Protein sectors: statistical coupling analysis versus conservation

, 2014
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors".
Colwell, Lucy J., Leibler, Stanislas, Tesileanu, Tiberiu   +2 more
core   +4 more sources

Complete Genome Sequence of a Putative Densovirus of the Asian Citrus Psyllid, Diaphorina citri. [PDF]

, 2016
Here, we report the complete genome sequence of a putative densovirus of the Asian citrus psyllid, Diaphorina citri Diaphorina citri densovirus (DcDNV) was originally identified through metagenomics, and here, we obtained the complete nucleotide sequence
Falk, Bryce W, Nigg, Jared C, Nouri, Shahideh   +2 more
core   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis

npj Biofilms and Microbiomes, 2017
Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.
Adrian Tett, Edoardo Pasolli, Stefania Farina, Duy Tin Truong, Francesco Asnicar, Moreno Zolfo, Francesco Beghini, Federica Armanini, Olivier Jousson, Veronica De Sanctis, Roberto Bertorelli, Giampiero Girolomoni, Mario Cristofolini, Nicola Segata   +13 more
doaj   +1 more source

Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion

mSphere, 2022
Heavy exposure to Mycobacterium tuberculosis, the etiologic agent of tuberculosis (TB) and among the top infectious killers worldwide, results in infection that is cleared, contained, or progresses to disease.
Jason D. Simmons, Kimberly A. Dill-McFarland, Catherine M. Stein, Phu T. Van, Violet Chihota, Thobani Ntshiqa, Pholo Maenetje, Glenna J. Peterson, Penelope Benchek, Mary Nsereko, Kavindhran Velen, Katherine L. Fielding, Alison D. Grant, Raphael Gottardo, Harriet Mayanja-Kizza, Robert S. Wallis, Gavin Churchyard, W. Henry Boom, Thomas R. Hawn   +18 more
doaj   +1 more source

Sequence information gain based motif analysis [PDF]

, 2015
Background: The detection of regulatory regions in candidate sequences is essential for the understanding of the regulation of a particular gene and the mechanisms involved.
Marco, Santiago, Maynou Fernández, Joan, Pairó, Erola, Perera Lluna, Alexandre   +3 more
core   +3 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source