Results 101 to 110 of about 3,077,972 (305)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Detecting and Locating a Changed Segment in a Binomial Sequence: Comparison
, 2005 A class of tests for testing a changed segment in a binomial sequence is proposed and an asymptotic behavior is established. A consistent procedure of estimating the length of a changed segment is proposed.
Zuokas, D.
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Improving phonetic alignment by handling secondary sequence structures [PDF]
, 2014 In traditional alignment analyses, sequences are only compared with regard to their primary structure. Here, the term primary structure refers to the order order of segments, whereby segments are understood as the smallest units of a sequence which ...
List, Johann-Mattis
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This chapter introduces Sequence Analysis (SA) as a set of tools for examining sequential categorical data, focusing on temporal processes. These processes are crucial in sociology and other social sciences, as they study how individuals, families, or organizations change over time or engage in different activities in one or more domains. SA allows for
Syed Mudasir Ahmad +2 more
+7 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
prot4EST: translating expressed sequence tags from neglected genomes [PDF]
, 2004 The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing errors and typically define incomplete transcripts, making downstream annotation difficult ...
Mark L Blaxter +3 more
core +1 more source
Communications BiologyThe fine-scale genetic structure within populations, focusing on demographic histories and migration patterns, has been explored previously. However, limited attention has been paid to understanding how genetic structure influences lifestyle and dietary ...
Yichi Chen +3 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source