Results 11 to 20 of about 2,264,396 (196)

Integrating sequence and structural biology with DAS [PDF]

BMC Bioinformatics, 2007
Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D, Kulesha Eugene, Down Thomas A, Prlić Andreas, Kähäri Andreas, Hubbard Tim JP   +5 more
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Epstein-Barr Virus Sequence Variation—Biology and Disease [PDF]

Pathogens, 2012
Some key questions in Epstein-Barr virus (EBV) biology center on whether naturally occurring sequence differences in the virus affect infection or EBV associated diseases. Understanding the pattern of EBV sequence variation is also important for possible
Stelios Tzellos, Paul J. Farrell
doaj   +3 more sources

Legume Biology: Sequence to Seeds [PDF]

Plant Physiology, 2007
Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R, O'Brian, Carroll P, Vance
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CLONEQC: lightweight sequence verification for synthetic biology [PDF]

Nucleic Acids Research, 2010
Synthetic biology projects aim to produce physical DNA that matches a designed target sequence. Chemically synthesized oligomers are generally used as the starting point for building larger and larger sequences. Due to the error rate of chemical synthesis, these oligomers can have many differences from the target sequence.
Lee, Pablo A., Dymond, Jessica S., Scheifele, Lisa Z., Richardson, Sarah M., Foelber, Katrina J., Boeke, Jef D., Bader, Joel S.   +6 more
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Sequence Alignment in Molecular Biology

Journal of Computational Biology, 1998
Molecular biology is becoming a computationally intense realm of contemporary science and faces some of the current grand scientific challenges. In its context, tools that identify, store, compare and analyze effectively large and growing numbers of bio-sequences are found of increasingly crucial importance.
Apostolico, Alberto, Fiancarlo, Raffaele
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Human Chromosome 7: DNA Sequence and Biology [PDF]

Science, 2003
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical ...
Scherer, Sw, Cheung, J, Macdonald, Jr, Osborne, Lr, Nakabayashi, K, Herbrick, J., Carson, Ar, Parker Katiraee, L, Skaug, J, Khaja, R, Zhang, J, Hudek, Ak, Li, M, Haddad, M, Duggan, Ge, Fernandez, Ba, Kanematsu, E, Gentles, S, Christopoulos, Cc, Choufani, S, Kwasnicka, D, Zheng, Xh, Lai, Z, Nusskern, D, Zhang, Q, Gu, Z, Lu, F, Zeesman, S, Nowaczyk, Mj, Teshima, I, Chitayat, D, Shuman, C, Weksberg, R, Zackai, Eh, Grebe, Ta, Cox, Sr, Kirkpatrick, Sj, Rahman, N, Friedman, Jm, Heng, Hhq, Pelicci, Pg, LO COCO, FRANCESCO, Belloni, E, Shaffer, Lg, Pober, B, Morton, Cc, Gusella, Jf, Bruns, Gap, Korf, Br, Quade, Bj, Ligon, Ah, Ferguson, H, Higgins, Aw, Leach, Nt, Herrick, Sr, Lemyre, E, Farra, Cg, Kim, H., Summers, Am, Gripp, Kw, Roberts, W, Szatmari, P, Winsor, Ejt, Grzeschik, K., Teebi, A, Minassian, Ba, Kere, J, Armengol, L, Pujana, Ma, Estivill, X, Wilson, Md, Koop, Bf, Tosi, S, Moore, Ge, Boright, Ap, Zlotorynski, E, Kerem, B, Kroisel, Pm, Petek, E, Oscier, Dg, Mould, Sj, Dohner, H, Dohner, K, Rommens, Jm, Vincent, Jb, Venter, Jc, Li, Pw, Mural, Rj, Adams, Md, Tsui, L.   +89 more
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What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail?

Viruses, 2015
Phage therapy, a practice widespread in Eastern Europe, has untapped potential in the combat against antibiotic-resistant bacterial infections. However, technology transfer to Western medicine is proving challenging. Bioinformatics analysis could help to
Henrike Zschach, Katrine G. Joensen, Barbara Lindhard, Ole Lund, Marina Goderdzishvili, Irina Chkonia, Guliko Jgenti, Nino Kvatadze, Zemphira Alavidze, Elizabeth M. Kutter, Henrik Hasman, Mette V. Larsen   +11 more
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Genomics and proteomics: a signal processor's tour [PDF]

, 2004
The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
core   +2 more sources

Cancer biology deciphered by single-cell transcriptomic sequencing [PDF]

Protein & Cell, 2021
AbstractTumors are complex ecosystems in which heterogeneous cancer cells interact with their microenvironment composed of diverse immune, endothelial, and stromal cells. Cancer biology had been studied using bulk genomic and gene expression profiling, which however mask the cellular diversity and average the variability among individual molecular ...
Yanmeng Li, Jianshi Jin, Fan Bai
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Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids

Bio-Protocol, 2020
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo, Deborah Ferrara, Cristina Potrich, Lorenzo Lunelli, Lia Vanzetti, Alessandro Provenzani, Manuela Basso, Alessandro Quattrone, Vito D'Agostino   +8 more
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