Results 11 to 20 of about 5,890,604 (383)
Integrating sequence and structural biology with DAS [PDF]
BMC Bioinformatics, 2007 Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D +5 more
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Connecting Sequence and Biology in the Laboratory Mouse [PDF]
Genome Research, 2003 The Mouse Genome Sequencing Consortium and the RIKEN Genome Exploration Research grouphave generated large sets of sequence data representing the mouse genome and transcriptome, respectively. These data provide a valuable foundation for genomic research.
Richard M. Baldarelli +26 more
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The DNA sequence and biology of human chromosome 19 [PDF]
Nature, 2004 Chromosome 19 has the highest gene density of all human chromosomes, more than double the genome-wide average. The large clustered gene families, corresponding high G + C content, CpG islands and density of repetitive DNA indicate a chromosome rich in biological and evolutionary significance.
Jane Grimwood +97 more
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Legume Biology: Sequence to Seeds [PDF]
Plant Physiology, 2007 Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R, O'Brian, Carroll P, Vance
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Surprising biology in uncharted microbial sequences [PDF]
, 2023 The microbiome, all microorganisms in their natural habitat, can be collected on filters and its DNA extracted. Sequencing of this metagenome allows us to observe microorganisms not under a microscope or in the lab but via their DNA and in their natural habitat, revealing who they are and what they can do.
F. A. Bastiaan von Meijenfeldt
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100th Anniversary of Macromolecular Science Viewpoint: Opportunities in the Physics of Sequence-Defined Polymers [PDF]
, 2020 Polymer science has been driven by ever-increasing molecular complexity, as polymer synthesis expands an already-vast palette of chemical and architectural parameter space.
Perry, Sarah L., Sing, Charles E.
core +3 more sources
The Multiple Sequence Alignment Problem in Biology [PDF]
SIAM Journal on Applied Mathematics, 1988 Summary: The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the different possible sequence alignments in order to find an optimal one for which the ``distance'' between sequences is minimum ...
Carrillo, Humberto, Lipman, David
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The EM Algorithm and the Rise of Computational Biology [PDF]
, 2010 In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link +3 more
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RBPSpot: Learning on appropriate contextual information for RBP binding sites discovery
iScience, 2021 Summary: Identifying the factors determining the RBP-RNA interactions remains a big challenge. It involves sparse binding motifs and a suitable sequence context for binding. The present work describes an approach to detect RBP binding sites in RNAs using
Nitesh Kumar Sharma +5 more
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Localization of T cell clonotypes using the Visium spatial transcriptomics platform
STAR Protocols, 2022 Summary: We present a protocol to localize T cell receptor clones using the Visium spatial transcriptomics platform. This approach permits simultaneous localization of both gene expression and T cell clonotypes in situ within tissue sections.
William H. Hudson, Lisa J. Sudmeier
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