Results 11 to 20 of about 1,180,805 (214)

Integrating sequence and structural biology with DAS [PDF]

BMC Bioinformatics, 2007
Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D, Kulesha Eugene, Down Thomas A, Prlić Andreas, Kähäri Andreas, Hubbard Tim JP   +5 more
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Towards an Encyclopaedia of Sequence Biology [PDF]

Linguistic Frontiers, 2018
Abstract In this review, I have presented several topics relevant to the present state and to the future state of the scientific field that I propose to call sequence biology (SB). In some pertinent publications, this field was called DNA linguistics. At the heart of SB lies a concept of a sequence code.
Alexander Bolshoy
openalex   +2 more sources

Epstein-Barr Virus Sequence Variation—Biology and Disease [PDF]

Pathogens, 2012
Some key questions in Epstein-Barr virus (EBV) biology center on whether naturally occurring sequence differences in the virus affect infection or EBV associated diseases. Understanding the pattern of EBV sequence variation is also important for possible
Stelios Tzellos, Paul J. Farrell
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Surprising biology in uncharted microbial sequences [PDF]

, 2023
The microbiome, all microorganisms in their natural habitat, can be collected on filters and its DNA extracted. Sequencing of this metagenome allows us to observe microorganisms not under a microscope or in the lab but via their DNA and in their natural habitat, revealing who they are and what they can do.
F. A. Bastiaan von Meijenfeldt
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Legume Biology: Sequence to Seeds [PDF]

Plant Physiology, 2007
Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R, O'Brian, Carroll P, Vance
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CLONEQC: lightweight sequence verification for synthetic biology [PDF]

Nucleic Acids Research, 2010
Synthetic biology projects aim to produce physical DNA that matches a designed target sequence. Chemically synthesized oligomers are generally used as the starting point for building larger and larger sequences. Due to the error rate of chemical synthesis, these oligomers can have many differences from the target sequence.
Lee, Pablo A., Dymond, Jessica S., Scheifele, Lisa Z., Richardson, Sarah M., Foelber, Katrina J., Boeke, Jef D., Bader, Joel S.   +6 more
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Sequence Alignment in Molecular Biology

Journal of Computational Biology, 1998
Molecular biology is becoming a computationally intense realm of contemporary science and faces some of the current grand scientific challenges. In its context, tools that identify, store, compare and analyze effectively large and growing numbers of bio-sequences are found of increasingly crucial importance.
Apostolico, Alberto, Fiancarlo, Raffaele
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Human Chromosome 7: DNA Sequence and Biology [PDF]

Science, 2003
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical ...
Scherer, Sw, Cheung, J, Macdonald, Jr, Osborne, Lr, Nakabayashi, K, Herbrick, J., Carson, Ar, Parker Katiraee, L, Skaug, J, Khaja, R, Zhang, J, Hudek, Ak, Li, M, Haddad, M, Duggan, Ge, Fernandez, Ba, Kanematsu, E, Gentles, S, Christopoulos, Cc, Choufani, S, Kwasnicka, D, Zheng, Xh, Lai, Z, Nusskern, D, Zhang, Q, Gu, Z, Lu, F, Zeesman, S, Nowaczyk, Mj, Teshima, I, Chitayat, D, Shuman, C, Weksberg, R, Zackai, Eh, Grebe, Ta, Cox, Sr, Kirkpatrick, Sj, Rahman, N, Friedman, Jm, Heng, Hhq, Pelicci, Pg, LO COCO, FRANCESCO, Belloni, E, Shaffer, Lg, Pober, B, Morton, Cc, Gusella, Jf, Bruns, Gap, Korf, Br, Quade, Bj, Ligon, Ah, Ferguson, H, Higgins, Aw, Leach, Nt, Herrick, Sr, Lemyre, E, Farra, Cg, Kim, H., Summers, Am, Gripp, Kw, Roberts, W, Szatmari, P, Winsor, Ejt, Grzeschik, K., Teebi, A, Minassian, Ba, Kere, J, Armengol, L, Pujana, Ma, Estivill, X, Wilson, Md, Koop, Bf, Tosi, S, Moore, Ge, Boright, Ap, Zlotorynski, E, Kerem, B, Kroisel, Pm, Petek, E, Oscier, Dg, Mould, Sj, Dohner, H, Dohner, K, Rommens, Jm, Vincent, Jb, Venter, Jc, Li, Pw, Mural, Rj, Adams, Md, Tsui, L.   +89 more
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Cancer biology deciphered by single-cell transcriptomic sequencing [PDF]

Protein & Cell, 2021
AbstractTumors are complex ecosystems in which heterogeneous cancer cells interact with their microenvironment composed of diverse immune, endothelial, and stromal cells. Cancer biology had been studied using bulk genomic and gene expression profiling, which however mask the cellular diversity and average the variability among individual molecular ...
Yanmeng Li, Jianshi Jin, Fan Bai
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The Multiple Sequence Alignment Problem in Biology [PDF]

SIAM Journal on Applied Mathematics, 1988
Summary: The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the different possible sequence alignments in order to find an optimal one for which the ``distance'' between sequences is minimum ...
Carrillo, Humberto, Lipman, David
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