Results 31 to 40 of about 4,078,643 (261)
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis
npj Biofilms and Microbiomes, 2017 Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.Adrian Tett, Edoardo Pasolli, Stefania Farina, Duy Tin Truong, Francesco Asnicar, Moreno Zolfo, Francesco Beghini, Federica Armanini, Olivier Jousson, Veronica De Sanctis, Roberto Bertorelli, Giampiero Girolomoni, Mario Cristofolini, Nicola Segata +13 moredoaj +1 more sourceHepatic depletion of nucleolar protein mDEF causes excessive mitochondrial copper accumulation associated with p53 and NRF1 activation
iScience, 2023 Summary: Copper is an essential component in the mitochondrial respiratory chain complex IV (cytochrome c oxidases). However, whether any nucleolar factor(s) is(are) involved in regulating the mitochondrial copper homeostasis remains unclear.Jinsong Wei, Shuai Wang, Haozhe Zhu, Wei Cui, Jianan Gao, Ce Gao, Bo Yu, Bojing Liu, Jun Chen, Jinrong Peng +9 moredoaj +1 more sourceIntegrative annotation of 21,037 human genes validated by full-length cDNA clones [PDF]
, 2004 The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited.Terwilliger Joseph D, Nagata, Naoki, Kuryshev, Vladimir, Eveno, E., Imbeaud, S., Makalowski, W., Yoshiyuki Suzuki, Sakai, Katsunaga, Graudens Esther, de Souza, S.J., Sakamoto Shigetaka, Thomas, M.A., Ashurst, Jennifer, Kanehisa Minoru, Shinsei Minoshima, Korn, B., Mitsuteru Nakao, Robert L Strausberg, Unneberg, P., Eveno Eric, Ren, S. -X, Lenhard, B., Shiba, Rie, Hilton Phillip, Sakate, Ryuichi, Bromberg Susan K, Gopal R. Gopinath, Nakai, K., Jia, Libin, Alexander Kanapin, Momoki Hirai, Barrero, R., Strausberg Robert L, Steward Charles, Suzuki, Yutaka, Okazaki, Yasushi, Makalowski Wojciech, Okido Toshihisa, Fukami-Kobayashi Kaoru, Satoshi Oota, Motohiko Tanino, Hide, Winston, R. Gopinath, Gopal, Auffray, C., de Souza, S., Shimoyama, Mary, Dubchak Inna, Osamu Ogasawara, Erimi Harada, Quackenbush, John, Jun-ichi Takeda, Steward, C., Kikuno, Reiko, Hirai, M., Isogai, T., Piero Carninci, Matsuda, Hideo, Ryuichi Sakate, Suzuki Yutaka, Kenta Nakai, Chen Zhu, Hiroaki Sakai, Shiba, R., Okubo, K., Nomura Nobuo, Sandro J. de Souza, Taylor Todd, Toshihisa Takagi, Thierry-Mieg Jean, Fukuchi Satoshi, Nagasaki, H., Hayashizaki, Yoshihide, Bellgard Matthew, Chelala Claude, Terwilliger, J., Bruford Elspeth, Apweiler Rolf, Christine Couillault, Takeya Kasukawa, Suzuki Mami, Nobuo Nomura, Sakai Katsunaga, Korn, Bernhard, Mulder, N., Amid, Clara, Schupp, Ingo, Kasukawa Takeya, Veeramachaneni, V., Wagner, L., Yura Kei, Annemarie Poustka, Yura, Kei, Ian Hopkinson, Hashimoto, Katsuyuki, Bono, H., Endo, T., Couillault, Christine, Elspeth Bruford, Bono Hidemasa, Ota Toshio, Reiko Kikuno, O'Donovan, C., Ota, M., Jia, L., Han Michael, Okazaki, Y., Shuang-Xi Ren, Tamura, T., Sakamoto, S., Bromberg, Susan K., Ohara, Osamu, Korn Bernhard, Hyang-Yoo, S., Nagata, N., Karavidopoulou Youla, Koyanagi, K.O., Soares, Bento, Tanaka, H., Charles Steward, Yamasaki, Chisato, Saitou Naruya, Yoo, H-S, Norikazu Yasuda, Imbeaud, Sandrine, Roberto A Barrero, Nishikawa Tetsuo, Izabela Makalowska, Jin Lihua, Nigam, Rajni, Gopinath, G. R., Motonori Ota, Stephen Sherry, Hiroshi Tanaka, Yayoi Kaneko, Jean Thierry-Mieg, Okada, Norihiro, Kelso, J. ; https://orcid.org/, Fukami-Kobayashi, K., Otsuki, Tetsuji, Yura, K., Ikeo, K., Hanaoka, Hideki, Rajni Nigam, Tanino, Motohiko, Sugano Sumio, Matthew Bellgard, Kaoru Fukami-Kobayashi, Oota Satoshi, Shimizu, Nobuyoshi, Sugano, Sumio, Satoshi Fukuchi, O'Donovan, Claire, Ren, S-X, Todd Taylor, Kimura Kouichi, Bonaldo, Maria de Fatima, Poustka, Annemarie, Koyanagi, K., Shimizu, N., Kanapin Alexander, Bono, Hidemasa, Chelala, Claude, Koyanagi, Kanako O., Devignes, M. -D, Stodolsky, M., Brookes, A., Strausberg, R., Danielle Thierry-Mieg, Stefan Wiemann, Eyras, Eduardo, Brookes, Anthony J., Mami Suzuki, Lukas Wagner, Hilton, Phillip, Barrero Roberto A, Suzuki Yoshiyuki, Sugawara Hideaki, Kasukawa, T., Yoshihide Hayashizaki, Mano, Shuhei, Craig Gough, Takashi Makino, Takahashi, Aiko, Shuhei Mano, Takashi Gojobori, Suzuki, Yoshiyuki, Libin Jia, Kousaku Okubo, Han, Michael, Koyanagi Kanako O, Hidemasa Bono, Inoko, Hidetoshi, Hinz Ursula, Auffray Charles, Strausberg, R.L., Yamaguchi-Kabata, Y., Devignes, Marie Dominique, Norihiro Okada, Hideki Hanaoka, Oota, S., Fujii Yasuyuki, Han, Ze-Guang, Isogai Takao, Kasprzyk, A., Ranajit Chakraborty, Itoh, Takeshi, Terwilliger, Joseph D., Florence Servant, Mulder, Nicola, Takahashi, A., Piatier-Tonneau, Dominique, Hirakawa Mika, R. Gopinath, G., Bromberg, S., Hinz, Ursula, Suwa Makiko, Hopkinson, I., Thierry-Mieg Danielle, Chelala, C., Mewes, Hans Werner, Amid, C., Hirakawa, Mika, Servant, Florence, Hishiki, T., Nomura, N., Steward, Charles, Tamiya, G., Rie Shiba, Hahn Yoonsoo, Fujii, Y., Tateno Yoshio, Sugawara, H., Ren, Shuang Xi, Naoki Nagata, Soares Bento, Hidetoshi Inoko, Sakai, H., Schupp, I., Sakamoto, Shigetaka, Lenhard Boris, Yasuda Norikazu, Nakai Kenta, Kim, S., Kersey Paul, Watanabe Shinya, de Bonaldo, M., Hishiki, Teruyoshi, Mariage-Samson, R., Toshinori Endo, Hishiki Teruyoshi, Bellgard, Matthew, Mano, S., Nishikawa, Tetsuo, Okido, T., Wiemann, S., Anne Estreicher, Hayashizaki, Y., Miyazaki, Satoru, Susan K Bromberg, Apweiler, R., Katsunaga Sakai, Han, M., Oishi Michio, Hide, W., Kanako O Koyanagi, Tetsuo Nishikawa, Nobuyoshi Shimizu, Carninci, Piero, Makino Takashi, Dubchak, Inna, Yoo, Hyang-Sook, Ren, S., Strausberg, R. L., Estreicher, A., Yamasaki Chisato, Eyras, E., Tanaka Hiroshi, Nagai, Keiichi, Wilming, Laurens, Phillip Hilton, Ota, T., Go, M., Wilming Laurens, Winston Hide, Hopkinson Ian, Yasuda, Norikazu, Graudens, Esther, Regine Mariage-Samson, Harada, Erimi, Suwa, Makiko, Claude Chelala, Sherry Stephen, Yamaguchi-Kabata, Yumi, Eduardo Eyras, Han, Z. -G, Chakraborty, Ranajit, Teruyoshi Hishiki, Yoo, H-S., Mariage-Samson, Regine, Piatier-Tonneau Dominique, Kim, Sangsoo, Takeda, Jun Ichi, Bento Soares, Poustka, A., Zhu Chen, Makalowska, Izabela, Okada, N., Youla Karavidopoulou, Amid Clara, Suzuki, M., Sakai, K., Unneberg, Per, Wiemann Stefan, Inna Dubchak, Taylor, T., Okido, Toshihisa, Charles Auffray, Kelso, J., Hirai Momoki, Jennifer Ashurst, Yasuyuki Fujii, Nigam, R., Nishikawa, Ken, Terwilliger, J.D., Gopal R Gopinath, Tetsuji Otsuki, Nakao Mitsuteru, Brookes Anthony J, Hahn, Y., Simpson, A.J., Debily, Marie-Anne, Sangsoo Kim, Imanishi Tadashi, Homma, Keiichi, Kasukawa, Takeya, Makalowska Izabela, Takeda, J-I, Yutaka Suzuki, Jin, Lihua, Terwilliger, J. D., Aiko Takahashi, Hyang-Yoo, Sook, Sakai Hiroaki, Shimizu Nobuyoshi, Michael A Thomas, Tadashi Imanishi, Esther Graudens, Paul Kersey, Stodolsky Marvin, Toshio Ota, Ren, Shuang-Xi, Carninci Piero, Tanaka, S., Imanishi, T., Yoshio Tateno, Simpson Andrew J, de Fatima Bonaldo, Maria, Yoo Hyang-Sook, Imbeaud Sandrine, Brookes, A.J., Kikuno Reiko, Tanaka, Susumu, Tamiya, Gen, de Souza Sandro J., Sugano, S., Tomohiro Yasuda, Wilming, L., Keiichi Nagai, Devignes, Marie-Dominique, Matsuda Hideo, Takeda, J. -I, Nishikawa, T., Thierry-Mieg, J., Hideki Nagasaki, Estreicher Anne, Harada, E., Ota, Toshio, Yumi Yamaguchi-Kabata, Kelso, Janet, Minoshima Shinsei, Tanaka, Hiroshi, Kimura, K., Ingo Schupp, Sumio Sugano, Piatier-Tonneau, D., Yasuda, T., Simpson, A. J., Minoru Kanehisa, Ren Shuang-Xi, Janet Kelso, Barrero, R.A., Eyras Jiménez, Eduardo, Kaneko Yayoi, Servant, F., Hideaki Sugawara, Tamura Takuro, Susumu Tanaka, Tonellato, Peter, Gopinath, Gopal R., Thomas Michael A, Poustka Annemarie, Sugawara, Hideaki, Sakai, Hiroaki, Nagata Naoki, Dominique Piatier-Tonneau, Gojobori Takashi, Oishi, M., Nagai Keiichi, Chisato Yamasaki, Koyanagi, K. O., Thomas, M. A., Ohtsubo, Masafumi, Shigetaka Sakamoto, Hanada Kousuke, Fukuchi, S., Andrew J Simpson, Chakraborty Ranajit, Sakate, R., Mewes Hans-Werner, Matsuda, H., Kaneko, Yayoi, Kasprzyk Arek, Hashimoto, K., Otsuki, T., Ursula Hinz, Keiichi Homma, Bellgard, M., Harada Erimi, Tanino Motohiko, Minoshima, Shinsei, R. Gopinath Gopal, Joseph D Terwilliger, Souza, Sandro J. de, Gopinath, G., Oota, Satoshi, Debily Marie-Anne, Kanapin, Alexander, Karavidopoulou, Y., De Fatima Bonaldo, M., Isogai, Takao, Per Unneberg, Okazaki Yasushi, Takeshi Itoh, Fukami-Kobayashi, Kaoru, Yoonsoo Hahn, Peter Tonellato, Hirakawa, M., Jin, L., Makino, Takashi, Thierry-Mieg, D., Brookes, A. J., Ohara Osamu, Gopinath, G.R., Takahashi Aiko, Bernhard Korn, Watanabe, S., Kazuho Ikeo, Takao Isogai, Okubo Kousaku, Unneberg, Per,, Souza, S., Yoshiyuki Sakaki, Ashurst, J., Michael Han, Kanehisa, Minoru, Gojobori, T., Barrero, R. A., de Souza, S. J., Sandrine Imbeaud, Bruford, Elspeth, Bromberg, S. K., Shimoyama, M., Makalowska, I., Simpson, A., Laurens Wilming, Devignes, M., Karavidopoulou, Youla, Han, Z-G., Otsuki Tetsuji, Hopkinson, Ian, Itoh Takeshi, Claire O'Donovan, Ogasawara, Osamu, Nakai, Kenta, Jia Libin, Okubo, Kousaku, Eveno, Eric, Shimoyama Mary, Unneberg Per, Hyang-Sook Yoo, Estreicher, Anne, Veeramachaneni, Vamsi, Servant Florence, Hans-Werner Mewes, Sakaki, Yoshiyuki, Quackenbush John, Sherry, S., Masafumi Ohtsubo, Veeramachaneni Vamsi, Kikuno, R., Wagner Lukas, Mika Hirakawa, Schupp Ingo, Vamsi Veeramachaneni, Ikeo Kazuho, Apweiler, Rolf, Kasprzyk, Arek, Sherry, Stephen, Takeda, J., Thierry-Mieg, Jean, Devignes Marie-Dominique, Eric Eveno, Nagai, K., Marie-Anne Debily, Yasuda, N., Mashima Jun, Carninci, P., Naruya Saitou, Shinya Watanabe, Mashima, J., Nakao, M., Satoru Miyazaki, Ohtsubo, M., Saitou, N., O'Donovan Claire, John Quackenbush, Kuryshev Vladimir, Miyazaki Satoru, Nishikawa, K., Nigam Rajni, Takagi, T., Han, Z., Kuryshev, V., Couillault, C., Yamaguchi-Kabata Yumi, Tamura, Takuro, Simpson, Andrew J., Watanabe, Shinya, Tanino, M., Tateno, Y., Hanaoka Hideki, Takagi, Toshihisa, Soares, B., Mulder Nicola, Mewes, H. -W, Bonaldo Maria de Fatima, Suzuki, Mami, Ikeo, Kazuho, Oishi, Michio, Mitiko Go, Lenhard, Boris, Okada Norihiro, Go, Mitiko, Homma Keiichi, Ota Motonori, Quackenbush, J., Nicola Mulder, Bromberg, S.K., Takeda Jun-ichi, Kersey, P., Rolf Apweiler, Suzuki, Y., Boris Lenhard, Vladimir Kuryshev, Hinz, U., Kanapin, A., Kei Yura, Saitou, Naruya, Chakraborty, R., Debily, Marie Anne, Ogasawara Osamu, Wagner, Lukas, Mewes, Hans-Werner, Taylor, Todd, Hanaoka, H., Gen Tamiya, Thomas, M., Miyazaki, S., Takuro Tamura, Kaneko, Y., Yasuda Tomohiro, Minoshima, S., Sakaki Yoshiyuki, Tanaka Susumu, Mano Shuhei, Yoo, H., Suwa, M., Ze-Guang Han, Tamiya Gen, Kouichi Kimura, Hashimoto Katsuyuki, Barrero, Roberto A., Sakaki, Y., Dubchak, I., Chen, Z., Debily, M., Fukuchi, Satoshi, Toshihisa Okido, Gough Craig, Fujii, Yasuyuki, Nishikawa Ken, Makiko Suwa, Nomura, Nobuo, Kersey, Paul, Auffray, Charles, Clara Amid, Sandro J de Souza, Gough, Craig, Shiba Rie, Tonellato, P., Mashima, Jun, Osamu Ohara, Wiemann, Stefan, Graudens, E., Ohara, O., Hanada, Kousuke, Endo Toshinori, Ohtsubo Masafumi, Sakate Ryuichi, Wojciech Makalowski, Homma, K., Hahn, Yoonsoo, Bruford, E., Gough, C., Go Mitiko, Yasuda, Tomohiro, Hirai, Momoki, Chen, Zhu, Nagasaki Hideki, Yasushi Okazaki, Imanishi, Tadashi, Nakao, Mitsuteru, Kimura, Kouichi, Nagasaki, Hideki, Mewes, H., Strausberg, Robert L., Hide Winston, Debily, M. -A, Stodolsky, Marvin, Kousuke Hanada, Thierry-Mieg, Danielle, Mewes, H-W, de Souza, Sandro J., Lihua Jin, Thomas, Michael A., Mary Shimoyama, Katsuyuki Hashimoto, Kim Sangsoo, Hayashizaki Yoshihide, Hilton, P., Anthony J Brookes, Mariage-Samson Regine, Jun Mashima, Ken Nishikawa, Takeda, Jun-ichi, Ashurst Jennifer, Yamasaki, C., Inoko, H., Makino, T., Arek Kasprzyk, Gojobori, Takashi, Makalowski, Wojciech, Hanada, K., Kanehisa, M., Couillault Christine, Michio Oishi, Eyras Eduardo, Marie-Dominique Devignes, Tateno, Yoshio, Tonellato Peter, Takagi Toshihisa, Marvin Stodolsky, Endo, Toshinori, Itoh, T., Bonaldo, M., Maria de Fatima Bonaldo, Han, Ze Guang, Ota, Motonori, Han Ze-Guang, Hideo Matsuda, Inoko Hidetoshi, Ogasawara, O., Kelso Janet, T Imanishi, T Gojobori, S Sugano, T Itoh, Hyang Sook Yoo, Sang Soo Kim +688 morecore +1 more sourceThe SH2 Domain Interaction Landscape
Cell Reports, 2013 Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.Michele Tinti, Lars Kiemer, Stefano Costa, Martin L. Miller, Francesca Sacco, Jesper V. Olsen, Martina Carducci, Serena Paoluzi, Francesca Langone, Christopher T. Workman, Nikolaj Blom, Kazuya Machida, Christopher M. Thompson, Mike Schutkowski, Søren Brunak, Matthias Mann, Bruce J. Mayer, Luisa Castagnoli, Gianni Cesareni +18 moredoaj +1 more sourceChronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells
iScience, 2023 Summary: We show that inactivating AMPK in a genetic medulloblastoma model depletes tumor stem cells and slows progression. In medulloblastoma, the most common malignant pediatric brain tumor, drug-resistant stem cells co-exist with transit-amplifying ...Daniel Shiloh Malawsky, Taylor Dismuke, Hedi Liu, Ethan Castellino, Jay Brenman, Biplab Dasgupta, Andrey Tikunov, Timothy R. Gershon +7 moredoaj +1 more sourceIdentification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers
Viruses, 2016 Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease.Jens Friis-Nielsen, Kristín Rós Kjartansdóttir, Sarah Mollerup, Maria Asplund, Tobias Mourier, Randi Holm Jensen, Thomas Arn Hansen, Alba Rey-Iglesia, Stine Raith Richter, Ida Broman Nielsen, David E. Alquezar-Planas, Pernille V. S. Olsen, Lasse Vinner, Helena Fridholm, Lars Peter Nielsen, Eske Willerslev, Thomas Sicheritz-Pontén, Ole Lund, Anders Johannes Hansen, Jose M. G. Izarzugaza, Søren Brunak +20 moredoaj +1 more source
