Results 41 to 50 of about 4,078,643 (261)

A high-throughput protocol for deamination of long single-stranded DNA and oligo pools containing complex sequences

STAR Protocols, 2023
Summary: Cytidine deaminases as DNA mutators play important roles in immunity and genome stability. Here, we present a high-throughput protocol for deamination of long single-stranded (ss) DNA or oligo pools containing complex sequences.
Yanyan Wang, Senxin Zhang, Xiaoqi Zheng, Leng-Siew Yeap, Fei-Long Meng   +4 more
doaj   +1 more source

FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses

Journal of Immunology Research, 2015
FluKB is a knowledge-based system focusing on data and analytical tools for influenza vaccine discovery. The main goal of FluKB is to provide access to curated influenza sequence and epitope data and enhance the analysis of influenza sequence diversity ...
Christian Simon, Ulrich J. Kudahl, Jing Sun, Lars Rønn Olsen, Guang Lan Zhang, Ellis L. Reinherz, Vladimir Brusic   +6 more
doaj   +1 more source

OrthoSelect: a protocol for selecting orthologous groups in phylogenomics [PDF]

, 2009
Background: Phylogenetic studies using expressed sequence tags (EST) are becoming a standard approach to answer evolutionary questions. Such studies are usually based on large sets of newly generated, unannotated, and error-prone EST sequences from ...
Schreiber Fabian, Fabian Schreiber, Morgenstern Burkhard, Erpenbeck Dirk, Pik, Kerstin, Pick, Kerstin, Morgenstern, Burkhard, Kerstin Pick, Schreiber, Fabian, Wörheide, Gert, Erpenbeck, Dirk, Burkhard Morgenstern, Wörheide Gert, Gert Wörheide, Dirk Erpenbeck, Woerheide, Gert, Pick Kerstin   +16 more
core   +1 more source

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]

, 1991
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Reddehase, Matthias J., Del Val, Margarita, Koszinowski, Ulrich H., Schlicht, Hans-Jürgen, Ruppert, Thomas, Margarita Del Val, Hans-Jürgen Schlicht, Thomas Ruppert, Matthias J. Reddehase, Ulrich H. Koszinowski   +9 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Predicting protein function by machine learning on amino acid sequences – a critical evaluation [PDF]

, 2007
Copyright @ 2007 Al-Shahib et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Gilbert, DR, Al-Shahib, A, Breitling, Rainer, Gilbert, D, Breitling, R., Ali Al-Shahib, Breitling, Rainer,, Al-Shahib, Ali, Rainer Breitling, Gilbert, David R., Breitling, R, Breitling Rainer, Shahib, Ali Al-,, Gilbert, D.R., Al-Shahib Ali, Gilbert, David R.,, David R Gilbert, Gilbert David R, Al-Shahib, A., Narváez Prado, Carlos Wilfredo   +19 more
core   +3 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Development of a Biocontained Toluene-Degrading Bacterium for Environmental Protection

Microbiology Spectrum, 2021
Biocontainment is a safeguard strategy for preventing uncontrolled proliferation of genetically engineered microorganisms (GEMs) in the environment. Biocontained GEMs are designed to survive only in the presence of a specific molecule.
Masahito Ishikawa, Takaaki Kojima, Katsutoshi Hori   +2 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Synthetic biology open language (SBOL) version 3.0.0

Journal of Integrative Bioinformatics, 2020
Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems.
Baig Hasan, Fontanarrosa Pedro, Kulkarni Vishwesh, McLaughlin James Alastair, Vaidyanathan Prashant, Bartley Bryan, Beal Jacob, Crowther Matthew, Gorochowski Thomas E., Grünberg Raik, Misirli Goksel, Scott-Brown James, Oberortner Ernst, Wipat Anil, Myers Chris J.   +14 more
doaj   +1 more source