Results 11 to 20 of about 2,275,975 (294)

Integrating sequence and structural biology with DAS [PDF]

open access: yesBMC Bioinformatics, 2007
Background The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.
Finn Robert D   +5 more
doaj   +4 more sources

Legume Biology: Sequence to Seeds [PDF]

open access: yesPlant Physiology, 2007
Research on legumes is driven, to a large extent, by their importance as food crops worldwide. Some 25% of the world's major crop production is derived from legumes, and more than one-third of humanity's nutritional nitrogen requirement comes from legumes.
Mark R, O'Brian, Carroll P, Vance
openaire   +2 more sources

Connecting Sequence and Biology in the Laboratory Mouse [PDF]

open access: yesGenome Research, 2003
The Mouse Genome Sequencing Consortium and the RIKEN Genome Exploration Research grouphave generated large sets of sequence data representing the mouse genome and transcriptome, respectively. These data provide a valuable foundation for genomic research.
Richard M, Baldarelli   +26 more
openaire   +2 more sources

Towards an Encyclopaedia of Sequence Biology [PDF]

open access: yesLinguistic Frontiers, 2018
Abstract In this review, I have presented several topics relevant to the present state and to the future state of the scientific field that I propose to call sequence biology (SB). In some pertinent publications, this field was called DNA linguistics. At the heart of SB lies a concept of a sequence code.
openaire   +1 more source

Sequence Alignment in Molecular Biology

open access: yesJournal of Computational Biology, 1998
Molecular biology is becoming a computationally intense realm of contemporary science and faces some of the current grand scientific challenges. In its context, tools that identify, store, compare and analyze effectively large and growing numbers of bio-sequences are found of increasingly crucial importance.
Apostolico, Alberto, Fiancarlo, Raffaele
openaire   +4 more sources

Impact of Nucleic Acid Sequencing on Viroid Biology [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
The early 1970s marked two breakthroughs in the field of biology: (i) The development of nucleotide sequencing technology; and, (ii) the discovery of the viroids. The first DNA sequences were obtained by two-dimensional chromatography which was later replaced by sequencing using electrophoresis technique.
Charith Raj Adkar-Purushothama   +1 more
openaire   +3 more sources

Genomics and proteomics: a signal processor's tour [PDF]

open access: yes, 2004
The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
core   +2 more sources

Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids

open access: yesBio-Protocol, 2020
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo   +8 more
doaj   +1 more source

A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

open access: yesiScience, 2021
Summary: Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage)
André Azevedo Reis Teixeira   +16 more
doaj   +1 more source

High‐throughput sequencing for biology and medicine

open access: yesMolecular Systems Biology, 2013
Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High‐throughput sequencing technologies are now routinely being applied to a wide range of important topics in biology and medicine, often allowing researchers to address important ...
Wendy Weijia Soon   +2 more
openaire   +3 more sources

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