Results 11 to 20 of about 4,078,643 (261)

BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]

, 2009
A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ittzés, Péter, Jakó, Éena, Horváth, Arnold, Podani, János, Ari, Eszter   +4 more
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What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail?

Viruses, 2015
Phage therapy, a practice widespread in Eastern Europe, has untapped potential in the combat against antibiotic-resistant bacterial infections. However, technology transfer to Western medicine is proving challenging. Bioinformatics analysis could help to
Henrike Zschach, Katrine G. Joensen, Barbara Lindhard, Ole Lund, Marina Goderdzishvili, Irina Chkonia, Guliko Jgenti, Nino Kvatadze, Zemphira Alavidze, Elizabeth M. Kutter, Henrik Hasman, Mette V. Larsen   +11 more
doaj   +1 more source

An evolutionary ratchet leading to loss of elongation factors in eukaryotes [PDF]

, 2014
Background The GTPase eEF1A is the eukaryotic factor responsible for the essential, universal function of aminoacyl-tRNA delivery to the ribosome.
Kamenski, Piotr, Atkinson, Gemma C.,, Atkinson, Gemma C., Soosaar, Axel, Hauryliuk, Vasili,, Ivan Chicherin, Martin Carr, Tenson, Tanel,, Vasili Hauryliuk, Carr, Martin, Tanel Tenson, Kamenski, Piotr,, Kuzmenko, Anton, Hauryliuk, Vasili, Tenson, Tanel, Kuzmenko, Anton,, Chicherin, Ivan,, Carr, Martin,, Piotr Kamenski, Gemma C Atkinson, Soosaar, Axel,, Anton Kuzmenko, Lund University., Axel Soosaar, Chicherin, Ivan   +24 more
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A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology [PDF]

, 2010
Conventional drug design embraces the "one gene, one drug, one disease" philosophy. Polypharmacology, which focuses on multi-target drugs, has emerged as a new paradigm in drug discovery.
Durrant, Jacob D., Xie, Lei, Wunder, Frank, Bourne, Philip E., Ferguson, Michael A. J., Haapalainen, Antti, Chen, Zhijun, Di Guilmi, Anne Marie, Amaro, Rommie E., McCammon, J. Andrew, Urbaniak, Michael D.   +10 more
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Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids

Bio-Protocol, 2020
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo, Deborah Ferrara, Cristina Potrich, Lorenzo Lunelli, Lia Vanzetti, Alessandro Provenzani, Manuela Basso, Alessandro Quattrone, Vito D'Agostino   +8 more
doaj   +1 more source

A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

iScience, 2021
Summary: Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage)
André Azevedo Reis Teixeira, Luis Rodriguez Carnero, Andréia Kuramoto, Fenny Hui Fen Tang, Carlos Hernique Gomes, Natalia Bueno Pereira, Léa Campos de Oliveira, Regina Garrini, Jhonatas Sirino Monteiro, João Carlos Setubal, Ester Cerdeira Sabino, Renata Pasqualini, Walter Colli, Wadih Arap, Maria Júlia Manso Alves, Edécio Cunha-Neto, Ricardo José Giordano   +16 more
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MOSAL : software tools for multiobjective sequence alignment [PDF]

, 2014
Multiobjective sequence alignment brings the advantage of providing a set of alignments that represent the trade-off between performing insertion/deletions and matching symbols from both sequences. Each of these alignments provide a potential explanation
Monsanto Pinheiro, Miguel, Maryam Abbasi, Luís LuísPaquete, Paquete, Luís, Pedro Matias, Luís Paquete, Abbasi, Maryam, Miguel Pinheiro, Matias, Pedro   +8 more
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Analysis of population structure and genetic diversity in low-variance Saimaa ringed seals using low-coverage whole-genome sequence data

STAR Protocols, 2023
Summary: This protocol demonstrates how a fragmented reference genome and low-coverage sequencing data can be efficiently utilized for population genetic analyses of a species with highly reduced genetic diversity.
Emmi Olkkonen, Ari Löytynoja
doaj   +1 more source

Genome sequence of the pea aphid Acyrthosiphon pisum [PDF]

, 2010
Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity.
Fenton, Brian, Schneider, M., Nazareth, LV, Smagghe, G., Eisen, Jonathan A., Hilgarth, RS, Hlavina, W., Gordon, K., Christiaens, Olivier, Moen, C., Jiang, H., Williamson, Michael, Vellozo, A, Altincicek, B, Gilbert, Don, Cortes, T, Wright, Rita A., Bickel, Ryan D, Aguilar, J, Wilson, Alex CC, Dang, P.M., Davis, G.K., Brault, V, Hilgarth, Roland S., Lu, Hsiao-Ling, Patel, BM, Vilcinskas, A, Parker, Ben J., Gerardo, Nicole M, Chacko, Joseph, The International Aphid Genomics Consortium, Duncan, Elizabeth J, Evans, J, Davies, T. G. E., Chen, H.-C., Fitzroy, Carol I. J., Monsion, Baptiste, Seah, S., Butts, Thomas, Anselme, C, Hurwitz, B., Robertson, Hugh M, Wilson, Megan, Pechuan, X., Rahbe, Yvan, Dombrovsky, A., Cass, Bodil, Pérez-Brocal, V., Carolan, J.C., Miyagishima, S-Y, Ollivier, M., Leonardo, Teresa, Wilson, M, Jones, D.H., Futami, R, Kushlan, P.F., Zhang, Jingkun, Gabisi, R.A., Douglas, AE, Price, D.R.G., Lu, H.-L., Gatehouse, John A., Price, Daniel R.G., Hauser, F, Ortiz-Rivas, Benjamin, Richards, S, He, X-L, Collin, O., Chandrabose, Mimi N, Thibaud-Nissen, Françoise Françoise, Futami, R., Chen, H-C, Pechuan, X, et al., Joshi, V, Tamborindeguy, Cecilia, Kamins, A, Ollivier, Morgane, Smith, J., Kiryutin, B, Collin, Olivier, Atsushi, Nakabachi, Huerta-Cepas, Jaime, Dinh, HH, Schwartz, Julia, Kaloshian, I., Ishikawa, Asano, Sattelle, D., Smagghe, G, Vieira, Filipe G, Dang, Phat M., van der Zee, Maurijn, Gilbert, D, Veenstra, Jan A., Fowler, Gerald R, Ermolaeva, O., Lee, SL, Tamames, J., Walsh, T.K., de Vos, Martin, Evans, Jay, Legeai, F, Ashton, Peter D., Gabisi, RA, Hlavina, W, Moen, Charles, Hunnicutt, L., Jaubert-Possamai, S, Kamins, A., Barribeau, Seth M., Hedges, D, Heckel, David G., Lozado, Ryan J, Liu, Y-S, Diaz, J, Nikoh, N, Singh, K, Zhou, J-J, Hilgarth, R.S., Wilson, Alexandra, Souvorov, Alexandre, Hume, J, Tamarit, Daniel,, Stafflinger, E, Colella, S., Stanke, M, Huerta-Cepas, J., Consortium, The International Aphid Genomics, Davies, TG Emyr, Wilson, ACC, Huerta-Cepas, J, Williams Jr., R.L., Kosarev, P., Miyagishima, Shin-ya, Nakabachi, A., Christiaens, O, Rispe, C., Singh, Karam, Davies, TGE, Lewis, Lora R., Dinh, H.H., Camara, F, Schwartz, J., Barribeau, S.M., Ishikawa, A, Gauthier, Jean Pierre, Caillaud, Marina, Ren, Q., Rozas, Julio, Muzny, D, Cass, B, Monsion, B, Parker, BJ, Mariotti, M., Leonardo, T., Douglas, Angela, Muzny, Donna, Srinivasan, Dayalan, Gerardo, NM, Reeck, Gerald R, Sagot, MF, Campbell, Peter, Jaubert-Possamai, S., Hunnicutt, Laura, Hitchens, Matthew E, Kamphuis, Lars G., Miura, T, Wilson, Alex C. C., Davis, Gregory K., Gabaldon, Toni, Ermolaeva, O, Vattathil, Selina, Davies, T G Emyr, Joshi, V., Ju, Ho-Jong, Field, Linda M, Schneider, Martina, Carolan, James C, Price, Daniel RG, Cortes, Teresa, Reardon, Karen T., Brisson, J.A., Morioka, M., Velarde, R., Williamson, Martin S, Moya, A., Charles, Hubert, Moya, A, Kapustin, Yuri, Pruitt, K., Heckel, David G, Santibanez, Jireh, Field, Linda M., Fowler, GR, Lee, Sandra L., Chacko, J, Chandrabose, M.N., Huybrechts, Jurgen, Hansen, Karina K, Robertson, HM, Parker, Ben J, Fitzroy, Carol I.J., Zhou, Jing-Jiang, Jr, WRL, Vincent-Monegat, Carole, Miura, T., Câmara, F., Smith, James, Macdonald, S., Heckel, D.G., Muzny, D., Cree, A, Iga, M, Chacko, J., Hunter, W, Cree, Andy, Jiang, H, Wilkinson, T.L., Gauthier, Jean-Pierre, Pechuan, Ximo, Kudo, Toshiaki, Grimmelikhuijzen, C.J.P., Morioka, M, Robertson, H.M., Kamphuis, L.G., Morioka, Mizue, Thomas, G., Tagu, Denis, Hitchens, Matthew E., Degnan, P, Van Der Zee, M., Barribeau, Seth M, Kaloshian, Isgouhi, Atamian, H., Gatehouse, John A, Stafflinger, E., Schneider, M, Alioto, T, Tamborindeguy, C, Maglott, Donna, Hines, S., Vilcinskas, A., Williamson, M.S., Lewis, Lora R, Marcet-Houben, M, Solovyev, V., Duncan, EJ, Wolstenholme, A, Maglott, D, Guigó, R., Martinez-Torres, D, Rider, Stanley Dean, Duncan, E., Hansen, Karina K., Gerardo, Nicole M., Lozado, Ryan J., Morgan, Margaret B., Dale, RP, Price, Daniel R. G., Ermolaeva, Olga, Murphy, T, Hedges, Dale, Jiang, Huaiyang, Rispe, Claude, Chavez, D, Dale, R.P., Gauthier, J-P, Vieira, F.G., Heddi, Abdelaziz, Miyagishima, S.-Y., Martinez-Torres, David, Kaloshian, I, Nikoh, Naruo, Stanke, Mario, International Aphid Genomics Consortium, Vos, Martin, De, Kiryutin, B., Lozado, RJ, Davies, T. G. Emyr, Field, L.M., Ferrier, David, Dinh, Huyen H, Legeai, F., Jhangian, Shalini N., Wright, R.A., Fitzroy, CIJ, Hume, J., Ren, Q, de Vos, M, Wilkinson, TL, Ortiz-Rivas, B., Carolan, JC, Walsh, TK, McCutcheon, John P., Pruitt, K, Pruitt, Kim, Okwuonu, Geoffrey O, Caillaud, M, Heckel, D., Bickel, R.D., Thomas, G, Chen, Hsiu Chuan, Ghanim, M, Gabisi, Ramatu Ayiesha, Ashton, Peter D, Fenton, B, Robertson, Hugh M., Heckel, DG, Sagot, Marie France, Burke, G., Colella, S, Jones, A., Tamarit, D., Gordon, K, Atamian, H, Altincicek, B., Thibaud-Nissen, F., Koga, R., Duncan, Elizabeth, van Fleet, Eric, Anselme, Caroline, Williams, Rex L., Hansen, KK, Joshi, Vandita, Patel, B.M., Fitzroy, C.I.J., Brault, Veronique, Williamson, Martin S., Rizk, Guillaume, Kushlan, Philip F, Ramsey, J, Latorre, A., Pu, L.-L., Camara, Francisco, Butts, T., Liu, Y.-S., Williamson, MS, Cottret, Ludovic, Price, DRG, Smith, J, Burke, Gaelen, Zhou, Jing Jiang, Cazzamali, G., Reardon, Karen T, Hansen, K.K., Alioto, T., Cazzamali, Giuseppe, Abdel-latief, Mohatmed, Wilson, M., Permal, E., Williamson, M., Wilson, A.C.C., Janssen, R., Hines, Sandra, Stafflinger, Elisabeth, Hunter, W., Permal, E, Nazareth, L.V., McCutcheon, John P, Moran, Nancy A, Brault, V., Velarde, R, Chavez, D., Fenton, B., Lozado, R.J., Llorens, Carlos, Jones, DH, Dang, Phat M, Ashton, PD, Nazareth, Lynne V, McGregor, A, Jones, Andrew, Williamson, S, Dao, Marvin Diep, Gauthier, J.-P., Lavenier, D., Dearden, Peter, Price, Daniel R G, Pu, Ling-Ling, Nguyen, Ngoc Bich, Ashton, P., Nicolas, Jacques, Jones, A, Rizk, G., Williamson, M, Thomas, Gavin, Morgan, MB, Edwards, Owain R., Channels, Ion, Campbell, P., Huybrechts, J, Reeck, GR, Jhangian, SN, Vattathil, S, Kosarev, P, Williamson, S., Morgan, M.B., Perez-Brocal, Vicente, Christiaens, O., Huang, W., Hedges, D., Jhangian, S.N., Moen, C, Hurwitz, B, Reeck, G.R., Permal, Emmanuelle, Spragg, Chelsea J., Llorens, C., Kapustin, Y, Pu, L-L, Gabaldon, T, Davis, GK, Grimmelikhuijzen, Cornelis J. P., Vieira, Filipe G., Gerardo, N.M., Gordon, Karl, Brisson, Jennifer A., Williamson, Sally, Charles, H, Seah, S, Zhang, Lan, Fowler, Gerald R., Hitchens, ME, Zee, Maurijn, Van Der, Srinivasan, D., Chavez, Dean, Douglas, A, Ruiz, San Juana, Liu, R, Kapustin, Y., Santibanez, J, Jr, RSD, Walsh, Thomas K, Willson, Alex C.C., Dao, M.D., Huang, Wenting, Edwards, OR, Chang, C.-C., Lewis, L.R., van der Zee, M, Douglas, A.E., McCutcheon, JP, Wilkinson, Thomas L., Parker, B.J., Lu, H-L, Murphy, T., Stanke, M., Kitts, P, Jander, G., Zhang, L, Rider, Stanley Dean, Jr., Zhang, J, Mariotti, M, Bell, S.N., Marcet-Houben, Marina, Dearden, P, Duncan, E.J., Chen, Hsiu-Chuan, Macdonald, Sandy, Janssen, R, Fukatsu, Takema, Gibbs, Richard A, Worley, K.C., Reeck, Gerald R., Rispe, C, Dao, MD, Diaz, J., Stern, David, Moya, Andres, Febvay, Gerard, Shigenobu, S, Okwuonu, GO, Macdonald, S, Reardon, KT, van Fleet, E, Shigenobu, Shuji, Cortés, T., Legeai, Fabrice, Latorre, Amparo, Atamian, Hagop, Ramsey, John, Fukatsu, T, Steffen, David, Jones, Derek H., Bell, Stephanie N, Jones, Derek H, Spragg, Chelsea J, He, Xiao Li, Richards, S., Huang, W, Gabaldón, T., Velarde, Rodrigo, Sagot, Marie-France, Tagu, D., Quesneville, H, Veenstra, JA, Miura, Toru, Febvay, G., Janssen, Ralf, Nicolas, J, Johnson, A.J., Butts, T, Ferrier, D., Febvay, G, Jhangian, Shalini N, Nakabachi, A, Hauser, F., Kamphuis, Lars G, Vellozo, A., Cass, B., Bell, Stephanie N., Hunter, Wayne, Vilcinskas, Andreas, He, X.-L., Santibanez, J., Int Aphid Genomics Consortium, Rozas Liras, Julio A., McGregor, Alistair, Kitts, Paul, Calevro, F., Ju, H.-J., Chang, Chun Che, Latorre, A, Field, L. M., Smadja, C., Dearden, P., Moran, Nancy A., Grimmelikhuijzen, Cornelis J.P., Aguilar, J., Bickel, Ryan D., Lewis, LR, Kudo, T, Hurwitz, Bonnie, Wright, Rita A, Duncan, Elizabeth J., Zhou, J.-J., Alioto, Tyler, Smagghe, Guy, Collin, O, Kushlan, Philip F., Ortiz-Rivas, B, Anselme, C., Abdel-latief, M, Kiryutin, Boris, Rahbe, Y, Robichon, A., Colella, Stefano, Iga, M., Gibbs, R.A., Okwuonu, Geoffrey O., Huybrechts, J., Hines, S, Hitchens, M.E., Veenstra, J.A., Heddi, A., Nguyen, N.B., Ashton, P, Chang, C-C, , International Aphid Genomics Consortium, Okwuonu, G.O., Kovar, Christie, Barribeau, Seth, Wolstenholme, A., Kosarev, Peter, Davis, Clay, Tagu, D, Tamborindeguy, C., Liu, Yih-shin, Wilson, Alex C.C., Fleet, Eric, Van, Sapojnikov, V., Jaubert-Possamai, Stephanie, Zhou, J-J., Sattelle, David, Hunnicutt, L, Nakabachi, Atsushi, Dombrovsky, Aviv, Tamarit, Daniel, Ollivier, M, Monsion, B., Quesneville, Hadi, Nguyen, NB, Murphy, Terence, Koga, R, Dinh, Huyen H., Ren, Qinghu, Rahbé, Y., Reeck, Gerald, Cree, A., Diaz, Jason, Pignatelli, Miguel, Dang, PM, Gibbs, RA, Ferrier, D, Spragg, C.J., Edwards, O.R., Wilson, Alex C C, Ramsey, J., Degnan, Patrick, Sapojnikov, Victor, Jaubert, Stéphanie, Gibbs, Richard A., Nazareth, Lynne V., Hume, Jennifer, Srinivasan, D, Bickel, RD, Calevro, Federica, Guigo, Roderic, Richards, Stephen, Pu, Ling Ling, Smadja, C, Campbell, P, Chandrabose, Mimi N., Brisson, Jennifer A, Grimmelikhuijzen, Cornelis JP, Tamames, J, Lavenier, Dominique, Morgan, Margaret B, Rider Jr., Stanley Dean, Ashton, Peter, Davis, C, Chang, Chun-che, Smadja, Carole, Warren, J.T., Cottret, L., Gatehouse, JA, Guigo, R, Solovyev, Victor, Robichon, A, Jander, Georg, Robichon, Alain, Heddi, A, Calevro, F, Mariotti, Marco, Vincent-Monegat, C., Gerado, N., Aguilar, Jose, Consortium, IAG, Worley, Kim C., Williams, Rex L Jr, Janssen, Ralf,, Lee, S.L., Walsh, Thomas K., Ruiz, SJ, Kamphuis, LG, Kovar, C., Ishikawa, A., Iga, Masatoshi, Hlavina, Wratko, Kushlan, PF, Thibaud-Nissen, Francoise, Singh, K., Quesneville, H., Johnson, AJ, Spragg, CJ, He, X-L., De Vos, M., Duncan, E, Miyagishima, Shin Ya, Kudo, T., Lopez, J, Koga, Ryuichi, Warren, James T, Rozas, J., Liu, Renhu, Steffen, D, Souvorov, A, Nikoh, N., Rider, Stanley Dean Jr, Kovar, C, Liu, R., Vincent-Monegat, C, Field, LM, Vattathil, S., Wright, RA, Kamins, Alexandra, Fowler, G.R., Llorens, C, Evans, J., Lu, Hsiao Ling, Edwards, Owain R, Veenstra, Jan A, Ju, H-J, Ghanim, M., Worley, KC, Warren, James T., Wolstenholme, Adrian, Stern, D, Jander, G, Sapojnikov, V, Ruiz, S.J., Nicolas, J., Warren, JT, Williams, Rex L., Jr., Marcet-Houben, M., Williams, Rex L, Grimmelikhuijzen, CJP, Schwartz, J, Bell, SN, Caillaud, M., Sagot, M.F., Vellozo, Augusto, Burke, G, Fitzroy, Carol IJ, Abdel-Latief, M., Zhang, J., Rizk, G, Douglas, Angela E., Dale, Richard P., Fukatsu, T., Perez-Brocal, V, Van Fleet, E., Davies, T.G.E., Seah, Stuart, Gatehouse, J. A., Ferrier, David Ellard Keith, Grimmelikhuijzen, Cornelis J P, McCutcheon, J.P., The International Aphid Genomics Consortium, Iagc, Carolan, James C., Gerardo, Nichole M., Gibbs , R., Sattelle, D, Pignatelli, M., Solovyev, V, Lee, Sandra L, Kitts, P., Davis, C., Steffen, D., Zhang, L., Cazzamali, G, Tamarit, D, Ju, Ho Jong, Thibaud-Nissen, F, Liu, Yih Shin, Shigenobu, S., Reardon, K.T., Moran, Nancy, Moran, NA, Stern, D., Barribeau, SM, Souvorov, A., Rider Jr., S.D., Vieira, FG, Gatehouse, J.A., Cottret, L, McGregor, A., Chandrabose, MN, He, Xiao-Li, Hauser, Frank, Worley, Kim C, Hilgarth, Roland S, Maglott, D., Pignatelli, M, Moran, N, Gilbert, D., Brisson, JA, Wilkinson, Thomas L, Dombrovsky, A, Dale, Richard P, Futami, Ricardo, Ghanim, Murad, Tamames, Javier, Davis, Gregory K, Patel, Bella Mayurkumar, Fitzroy, Carol I J, Moran, N., Martínez-Torres, D., Lavenier, D, Williamson, M. S., Rozas, J, Lopez, J., Leonardo, T, Altincicek, Boran, Charles, H., Degnan, P., Lopez, John, Douglas, Angela E, Johnson, Angela Jolivet, Williams, RL, Rider, SD, Guigó Serra, Roderic, null null, Richards, Stephan   +783 more
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Novel bacteriophages containing a genome of another bacteriophage within their genomes [PDF]

, 2012
The work was funded by the Scottish Government’s Rural and Environment Science and Analytical Services (RESAS) DivisionA novel bacteriophage infecting Staphylococus pasteuri was isolated during a screen for phages in Antarctic soils.
Makarova Kira S., Koonin, Eugene V, Peter J Cock, Torrance Lesley, Kira S Makarova, Swanson, Maud M, Lesley Torrance, Torrance, Lesley, Reavy Brian, Hopkins, David W, Reavy, Brian, Hopkins, David W., Michael Taliansky, Cock, Peter J, Hopkins David W., Makarova, Kira S, Maud M Swanson, Swanson, Maud M., Makarova, Kira S., Koonin, Eugene V., Koonin Eugene V., Swanson Maud M., Taliansky, Michael, Cock Peter J., David W Hopkins, Taliansky Michael, Cock, Peter J., Brian Reavy, Eugene V Koonin   +28 more
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