Results 21 to 30 of about 5,890,604 (383)
Flexible RNA design under structure and sequence constraints using formal languages [PDF]
, 2013 The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure.
Denise, Alain +5 more
core +5 more sources
Sequence Alignment in Molecular Biology
Journal of Computational Biology, 1998 Molecular biology is becoming a computationally intense realm of contemporary science and faces some of the current grand scientific challenges. In its context, tools that identify, store, compare and analyze effectively large and growing numbers of bio-sequences are found of increasingly crucial importance.
Apostolico, Alberto, Fiancarlo, Raffaele
openaire +4 more sources
What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail?
Viruses, 2015 Phage therapy, a practice widespread in Eastern Europe, has untapped potential in the combat against antibiotic-resistant bacterial infections. However, technology transfer to Western medicine is proving challenging. Bioinformatics analysis could help to
Henrike Zschach +11 more
doaj +1 more source
A Draft Genome Sequence of Nicotiana benthamiana to Enhance Molecular Plant-Microbe Biology Research
Molecular Plant-Microbe Interactions, 2012 Aureliano Bombarely +5 more
openalex +3 more sources
iScience, 2021 Summary: Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage)
André Azevedo Reis Teixeira +16 more
doaj +1 more source
High‐throughput sequencing for biology and medicine
Molecular Systems Biology, 2013 Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High‐throughput sequencing technologies are now routinely being applied to a wide range of important topics in biology and medicine, often allowing researchers to address important ...
Wendy Weijia Soon +2 more
openaire +3 more sources
Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids
Bio-Protocol, 2020 Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo +8 more
doaj +1 more source
STAR Protocols, 2023 Summary: This protocol demonstrates how a fragmented reference genome and low-coverage sequencing data can be efficiently utilized for population genetic analyses of a species with highly reduced genetic diversity.
Emmi Olkkonen, Ari Löytynoja
doaj +1 more source
Biology of Genomes: making sense of sequence [PDF]
Genome Medicine, 2009 A report on the Biology of Genomes meeting held at Cold Spring Harbor Laboratory, NY, USA, 5-9 May 2009.
openaire +2 more sources
CLONEQC: lightweight sequence verification for synthetic biology [PDF]
Nucleic Acids Research, 2010 Synthetic biology projects aim to produce physical DNA that matches a designed target sequence. Chemically synthesized oligomers are generally used as the starting point for building larger and larger sequences. Due to the error rate of chemical synthesis, these oligomers can have many differences from the target sequence.
Lee, Pablo A. +6 more
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