Results 71 to 80 of about 2,264,396 (196)
A topological approach for protein classification
, 2015 Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology.
Cang, Zixuan +5 more
core +1 more source
Predicting translation initiation rates for designing synthetic biology
Frontiers in Bioengineering and Biotechnology, 2014 In synthetic biology, precise control over protein expression is required in order to construct functional biological systems. A core principle of the synthetic biology approach is model-guided design and, based on biological understanding of the process,
Benjamin eReeve +5 more
doaj +1 more source
Bacterial epidemiology and biology - lessons from genome sequencing [PDF]
Genome Biology, 2011 Next-generation sequencing has ushered in a new era of microbial genomics, enabling the detailed historical and geographical tracing of bacteria. This is helping to shape our understanding of bacterial evolution.
Parkhill, Julian, Wren, Brendan W
openaire +3 more sources
A One-Year Introductory Biology Majors’ Lab Sequence Incorporating
Journal of Microbiology & Biology Education, 2019 The introduction of Vision and Change by AAAS and the recommendation that biology departments amend their curricula to focus on key concepts and skills necessary for graduates have led to a re-envisioning of introductory curricula across the nation. Many
Merrilee F. Guenther +2 more
doaj +1 more source
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor [PDF]
, 2009 In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic.
David Westaway +4 more
core +1 more source
Applications of next‐generation sequencing in plant biology [PDF]
American Journal of Botany, 2012 The last several years have seen revolutionary advances in DNA sequencing technologies with the advent of next‐generation sequencing (NGS) techniques. NGS methods now allow millions of bases to be sequenced in one round, at a fraction of the cost relative to traditional Sanger sequencing.
Ashley N, Egan +2 more
openaire +2 more sources
Protocol for analysis of single-cell sequencing data by Seqtometry
STAR ProtocolsSummary: Seqtometry (sequencing-to-measurement) is an analytical platform for single-cell analysis based on direct profiling of gene expression and accessibility achieved by advanced scoring with gene signatures.
Robert Kousnetsov, Daniel Hawiger
doaj +1 more source
A two-base encoded DNA sequence alignment problem in computational biology [PDF]
, 2009 The recent introduction of instruments capable of producing millions of DNA sequence reads in a single run is rapidly changing the landscape of genetics.
Chang, Jen-Mei +12 more
core
Protocol for constructing glycan biosynthetic networks using glycowork
STAR ProtocolsSummary: Glycans, present across all domains of life, comprise a wide range of monosaccharides assembled into complex, branching structures. Here, we present an in silico protocol to construct biosynthetic networks from a list of observed glycans using ...
Jon Lundstrøm +2 more
doaj +1 more source
MEMOFinder: combining _de_ _novo_ motif prediction methods with a database of known motifs [PDF]
, 2008 *Background:* Methods for finding overrepresented sequence motifs are useful in several key areas of computational biology. They aim at detecting very weak signals responsible for biological processes requiring robust sequence identification like ...
Bartek Wilczynski +2 more
core +2 more sources