Results 71 to 80 of about 1,274,222 (313)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

BioSeq-Analysis2.0: an updated platform for analyzing DNA, RNA and protein sequences at sequence level and residue level based on machine learning approaches

open access: yesNucleic Acids Research, 2019
As the first web server to analyze various biological sequences at sequence level based on machine learning approaches, many powerful predictors in the field of computational biology have been developed with the assistance of the BioSeq-Analysis. However,
B. Liu, Xin Gao, Han Zhang
semanticscholar   +1 more source

The international nucleotide sequence database collaboration

open access: yesNucleic Acids Res., 2020
The International Nucleotide Sequence Database Collaboration (INSDC; http://www.insdc.org/) has been the core infrastructure for collecting and providing nucleotide sequence data and metadata for >30 years.
Masanori Arita   +2 more
semanticscholar   +1 more source

Impact of the rumen microbiome on milk fatty acid composition of Holstein cattle

open access: yesGenetics Selection Evolution, 2019
Background Fatty acids (FA) in bovine milk derive through body mobilization, de novo synthesis or from the feed via the blood stream. To be able to digest feedstuff, the cow depends on its rumen microbiome. The relative abundance of the microbes has been
Bart Buitenhuis   +6 more
doaj   +1 more source

Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome

open access: yesiScience, 2023
Summary: Alternative transcription increases transcriptome complexity by expression of multiple transcripts per gene. Annotation and quantification of transcripts using short-read sequencing is non-trivial.
Christoph Andreas Engelhard   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The international nucleotide sequence database collaboration (INSDC): enhancing global participation.

open access: yesNucleic Acids Research
The members of the International Nucleotide Sequence Database Collaboration (INSDC; https://insdc.org) have built systems to collect, archive and disseminate sequence data for more than four decades.
I. Karsch-Mizrachi   +7 more
semanticscholar   +1 more source

ISEScan: automated identification of insertion sequence elements in prokaryotic genomes

open access: yesBioinform., 2017
Motivation The insertion sequence (IS) elements are the smallest but most abundant autonomous transposable elements in prokaryotic genomes, which play a key role in prokaryotic genome organization and evolution.
Zhiqun Xie, Haixu Tang
semanticscholar   +1 more source

Predicting translation initiation rates for designing synthetic biology

open access: yesFrontiers in Bioengineering and Biotechnology, 2014
In synthetic biology, precise control over protein expression is required in order to construct functional biological systems. A core principle of the synthetic biology approach is model-guided design and, based on biological understanding of the process,
Benjamin eReeve   +5 more
doaj   +1 more source

From cheek swabs to consensus sequences : an A to Z protocol for high-throughput DNA sequencing of complete human mitochondrial genomes [PDF]

open access: yes, 2014
Background: Next-generation DNA sequencing (NGS) technologies have made huge impacts in many fields of biological research, but especially in evolutionary biology. One area where NGS has shown potential is for high-throughput sequencing of complete mtDNA
Matisoo-Smith, Elizabeth A   +83 more
core   +1 more source

Home - About - Disclaimer - Privacy