Results 81 to 90 of about 5,758,485 (356)
RBPSpot: Learning on appropriate contextual information for RBP binding sites discovery
iScience, 2021 Summary: Identifying the factors determining the RBP-RNA interactions remains a big challenge. It involves sparse binding motifs and a suitable sequence context for binding. The present work describes an approach to detect RBP binding sites in RNAs using
Nitesh Kumar Sharma +5 more
doaj
Rural Education and the teaching of genetics: an investigative didactic possibility
Revista Brasileira de Educação do Campo, 2021 Research related to the genome project, cloning and genetically modified organisms are present inside and outside the school. Such subjects deserve attention in the teaching of genetics due to the difficulties presented by the students, regarding the ...
Kássia Paula Oliveira da Silva +2 more
doaj +1 more source
Profile Context-Sensitive HMMs for Probabilistic Modeling of Sequences With Complex Correlations [PDF]
, 2006 The profile hidden Markov model is a specific type of HMM that is well suited for describing the common features of a set of related sequences. It has been extensively used in computational biology, where it is still one of the most popular tools.
Vaidyanathan, P. P., Yoon, Byung-Jun
core +2 more sources
More Mouldy Data: Another mycoplasma gene jumps the silicon barrier into the human genome
, 2011 The human genome sequence database contains DNA sequences very like those of mycoplasma molds. It appears such moulds infect not only molecular Biology laboratories but were picked up by experimenters from contaminated samples and inserted into GenBank ...
Arno, M. J., Langdon, W. B.
core +1 more source
Decoding Sequence Classification Models for Acquiring New Biological Insights [PDF]
, 2010 Classifying biological sequences is one of the most important tasks in computational biology. In the last decade, support vector machines (SVMs) in combination with sequence kernels have emerged as a de-facto standard.
Andreas Kothmeier +5 more
core +2 more sources
Applications of next‐generation sequencing in plant biology [PDF]
American Journal of Botany, 2012 The last several years have seen revolutionary advances in DNA sequencing technologies with the advent of next‐generation sequencing (NGS) techniques. NGS methods now allow millions of bases to be sequenced in one round, at a fraction of the cost relative to traditional Sanger sequencing.
Ashley N. Egan +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Localization of T cell clonotypes using the Visium spatial transcriptomics platform
STAR Protocols, 2022 Summary: We present a protocol to localize T cell receptor clones using the Visium spatial transcriptomics platform. This approach permits simultaneous localization of both gene expression and T cell clonotypes in situ within tissue sections.
William H. Hudson, Lisa J. Sudmeier
doaj
Dynamics of Unperturbed and Noisy Generalized Boolean Networks
, 2009 For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems.
Darabos, Christian +2 more
core +1 more source
CLARK: fast and accurate classification of metagenomic and genomic sequences using discriminative k-mers. [PDF]
, 2015 BackgroundThe problem of supervised DNA sequence classification arises in several fields of computational molecular biology. Although this problem has been extensively studied, it is still computationally challenging due to size of the datasets that ...
Close, Timothy J +3 more
core +2 more sources