Results 81 to 90 of about 2,213,999 (337)

Techniques for RNA in vivo imaging in plants [PDF]

open access: yes, 2014
Since the discovery of small RNAs and RNA silencing, RNA biology has taken a centre stage in cell and developmental biology. Small RNAs, but also mRNAs and other types of cellular and viral RNAs are processed at specific subcellular localizations.
Tilsner, Jens
core   +1 more source

A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

open access: yesiScience, 2021
Summary: Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage)
André Azevedo Reis Teixeira   +16 more
doaj  

Surprising biology in uncharted microbial sequences

open access: yes, 2023
The microbiome, all microorganisms in their natural habitat, can be collected on filters and its DNA extracted. Sequencing of this metagenome allows us to observe microorganisms not under a microscope or in the lab but via their DNA and in their natural habitat, revealing who they are and what they can do.
openaire   +3 more sources

Applications of next‐generation sequencing in plant biology [PDF]

open access: yesAmerican Journal of Botany, 2012
The last several years have seen revolutionary advances in DNA sequencing technologies with the advent of next‐generation sequencing (NGS) techniques. NGS methods now allow millions of bases to be sequenced in one round, at a fraction of the cost relative to traditional Sanger sequencing.
Ashley N. Egan   +2 more
openaire   +3 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Are there laws of genome evolution? [PDF]

open access: yes, 2011
Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables.
Koonin, Eugene V.
core   +4 more sources

A Hands-On Activity to Demonstrate the Central Dogma of Molecular Biology Via a Simulated VDJ Recombination Activity

open access: yesJournal of Microbiology & Biology Education, 2017
Essential or enduring understandings are often defined as the underlying core concepts or “big ideas” we’d like our students to remember when much of the course content has been forgotten.
Pamela A. Marshall
doaj   +1 more source

Rural Education and the teaching of genetics: an investigative didactic possibility

open access: yesRevista Brasileira de Educação do Campo, 2021
Research related to the genome project, cloning and genetically modified organisms are present inside and outside the school. Such subjects deserve attention in the teaching of genetics due to the difficulties presented by the students, regarding the ...
Kássia Paula Oliveira da Silva   +2 more
doaj   +1 more source

Biophysical Sequence Analysis of Functional Differences of Piezo1 and Piezo2 [PDF]

open access: yesarXiv, 2022
Because of their large size and widespread mechanosensitive interactions the only recently discovered titled transmembrane proteins have attracted much attention. Here we present and discuss their hydropathic profiles using a new method of sequence analysis.
arxiv  

Length distribution of sequencing by synthesis: fixed flow cycle model [PDF]

open access: yesJournal of mathematical biology 67 (2), 389-410, 2013, 2014
Sequencing by synthesis is the underlying technology for many next-generation DNA sequencing platforms. We developed a new model, the fixed flow cycle model, to derive the distributions of sequence length for a given number of flow cycles under the general conditions where the nucleotide incorporation is probabilistic and may be incomplete, as in some ...
arxiv   +1 more source

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