Results 81 to 90 of about 2,264,396 (196)
AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
PLoS Biology, 2023 In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy ...
Hallvard Lauritz Olsvik, Terje Johansen
doaj
Protocol for genetic load analysis in caribou using a modified genomic evolutionary rate profiling
STAR ProtocolsSummary: Here, we present a protocol to analyze genetic load in caribou (Rangifer tarandus) using a modified version of the genomic evolutionary rate profiling (GERP) program.
Rebecca S. Taylor +3 more
doaj +1 more source
Guide for phenotype-specific profiling of DNA G-quadruplex-regulated genes
STAR ProtocolsSummary: DNA G-quadruplex (G4) is a non-canonical four-stranded secondary structure that has been shown to play a role in epigenetic modulation of gene expression.
Zhuoyang Zhao +3 more
doaj +1 more source
Surprising biology in uncharted microbial sequences
, 2023 The microbiome, all microorganisms in their natural habitat, can be collected on filters and its DNA extracted. Sequencing of this metagenome allows us to observe microorganisms not under a microscope or in the lab but via their DNA and in their natural habitat, revealing who they are and what they can do.
openaire +3 more sources
Random model for RNA interference yields scale free network
, 2003 We introduce a random bit-string model of post-transcriptional genetic regulation based on sequence matching. The model spontaneously yields a scale free network with power law scaling with $ \gamma=-1$ and also exhibits log-periodic behaviour.
Balcan, Duygu, Erzan, Ayse
core +1 more source
Molecular Systems Biology, 2014 Our current understanding of how natural genetic variation affects gene expression beyond well‐annotated coding genes is still limited. The use of deep sequencing technologies for the study of expression quantitative trait loci (eQTLs) has the potential ...
Mathieu Clément‐Ziza +12 more
doaj +1 more source
A stable backbone for the fungi [PDF]
, 2009 Fungi are abundant in the biosphere. They have fascinated mankind as far as written history goes and have considerably influenced our culture. In biotechnology, cell biology, genetics, and life sciences in general fungi constitute relevant model ...
Anne Kupczok +7 more
core +1 more source
Integer Linear Programming for Sequence Problems: A general approach to reduce the problem size [PDF]
, 2016 Sequence problems belong to the most challenging interdisciplinary topics of the actuality. They are ubiquitous in science and daily life and occur, for example, in form of DNA sequences encoding all information of an organism, as a text (natural or ...
Zörnig, Peter
core
Synthetic Biology Open Language (SBOL) Version 2.1.0
Journal of Integrative Bioinformatics, 2016 Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems.
Beal Jacob +22 more
doaj +1 more source
Meeting highlights: genome sequencing and biology 2001.
Comparative and functional genomics, 2001 We bring you a report from the CSHL Genome Sequencing and Biology Meeting, which has a long and prestigious history. This year there were sessions on large-scale sequencing and analysis, polymorphisms (covering discovery and technologies and mapping and analysis), comparative genomics of mammalian and model organism genomes, functional genomics and ...
openaire +2 more sources