Results 61 to 70 of about 335,085 (264)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Channel estimation for time varying channel based on decision directed technique in OFDM mobile systems

open access: yesTongxin xuebao, 2006
A channel estimation method was proposed based on decision directed technique and pilot tracking for OFDM WLANS with mobile terminals. The result of training sequence based estimation was used as the initialization of decision directed technique.
CHEN Hui, CHEN Xiao-guang
doaj   +2 more sources

Convolutional Gated Recurrent Unit–Recurrent Neural Network for State-of-Charge Estimation of Lithium-Ion Batteries

open access: yesIEEE Access, 2019
For most deep learning practitioners, recurrent networks are often used for sequence modeling. However, recent researches indicate that convolutional architectures may be used to optimize recurrent networks on some machine translation tasks.
Zhelin Huang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Improved Method for Interleaving Parameter Estimation in a Non-Cooperative Context

open access: yesIEEE Access, 2019
In a non-cooperative context, a sequence acquired from remote sensing through satellites and aircraft can be recognized as an unknown sequence to a receiver who lacks the information of the transmission parameters.
Geunbae Kim, Mingyu Jang, Dongweon Yoon
doaj   +1 more source

Attention-Based Sequence Learning Model for Travel Time Estimation

open access: yesIEEE Access, 2020
Travel time estimation (TTE) on a specific route is a challenging task since the complex road network structure and hard-captured temporal patterns. Many excellent methods have been proposed to address the aforementioned problems.
Zhong Wang   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Chromatic Dispersion Estimation Based on CAZAC Sequence for Optical Fiber Communication Systems

open access: yesIEEE Access, 2019
We propose a chromatic dispersion (CD) estimation method based on constant amplitude zero-autocorrelation (CAZAC) sequence and fractional Fourier transform (FrFT) algorithm for optical fiber communication systems, which extends the application of CAZAC ...
Feilong Wu   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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