Results 51 to 60 of about 334,418 (265)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Typical Algorithms for Estimating Hurst Exponent of Time Sequence: A Data Analyst’s Perspective
IEEE AccessThe Hurst exponent is a significant metric for characterizing time sequences with long-term memory property and it arises in many fields such as physics, engineering, mathematics, statistics, economics, psychology, and so on.
Hong-Yan Zhang +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Haplotype Estimation Using Sequencing Reads [PDF]
The American Journal of Human Genetics, 2013 High-throughput sequencing technologies produce short sequence reads that can contain phase information if they span two or more heterozygote genotypes. This information is not routinely used by current methods that infer haplotypes from genotype data.
Delaneau, O +4 more
openaire +3 more sources
An Anti-Interference Synchronization for OFDM Systems Based on Scrambling Sequence
IEEE Access, 2019 To improve the performance of the synchronization in OFDM systems in the presence of interference, a new synchronization algorithm based on scrambling sequence is proposed in this paper, which redesigns the training sequence with the constant amplitude ...
Min Yang, Fanglin Gu, Jun Liu, Ling Wang
doaj +1 more source
Journal of Modern Power Systems and Clean Energy, 2020 The estimation of sequence or symmetrical components and frequency in three-phase unbalanced power system is of great importance for protection and relay.
Umamani Subudhi +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A note on density estimation for binary sequences [PDF]
Statistics & Probability Letters, 2013 A histogram estimate of the Radon-Nikodym derivative of a probability measure with respect to a dominating measure is developed for binary sequences in $\{0,1\}^{\mathbb{N}}$. A necessary and sufficient condition for the consistency of the estimate in the mean-square sense is given.
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source