Results 131 to 140 of about 775,502 (352)

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

Advanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji, Xu Liu, Shuai Zhao, Sihan Zhou, Yufan Yang, Ping Zhang, Yu Shi, Wei Qin, Guibing Zhu, Yongguan Zhu, Yanzheng Gao, Jiandong Jiang, Baozhan Wang   +12 more
wiley   +1 more source

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

Journal of Biological Chemistry, 1978
E. Rinderknecht, R. Humbel
semanticscholar   +1 more source

The Site-Specific Amino Acid Preferences of Homologous Proteins Depend on Sequence Divergence

Genome Biology and Evolution, 2018
The propensity of protein sites to be occupied by any of the 20 amino acids is known as site-specific amino acid preferences (SSAP). Under the assumption that SSAP are conserved among homologs, they can be used to parameterize evolutionary models for the reconstruction of accurate phylogenetic trees.
openaire   +2 more sources

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

Advanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo, Zihua Guo, Yi Zhou, Yunhui Zhang, Haojin Cheng, Rebecca Devine, Chuang Sun, Ronghua Liu, Yanfen Zheng, Andrew J. Gates, Jonathan D. Todd, Xiao‐Hua Zhang   +11 more
wiley   +1 more source

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

Proceedings of the National Academy of Sciences of the United States of America, 1983
H. Marquardt, M. Hunkapiller, Leroy Hood, D. Twardzik, J. D. Larco, J. Stephenson, G. Todaro   +6 more
semanticscholar   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Genetic Characterization and Phylogeographic Analysis of the First H13N6 Avian Influenza Virus Isolated from Vega Gull in South Korea

Viruses
Avian influenza virus (AIV) is a pathogen with zoonotic and pandemic potential. Migratory birds are natural reservoirs of all known subtypes of AIVs, except for H17N10 and H18N11, and they have been implicated in previous highly pathogenic avian ...
Rochelle A. Flores, Paula Leona T. Cammayo-Fletcher, Binh T. Nguyen, Andrea Gail M. Villavicencio, Seung Yun Lee, Yongwoo Son, Jae-Hoon Kim, Kwang Il Park, Won Gi Yoo, Yeung Bae Jin, Wongi Min, Woo H. Kim   +11 more
doaj   +1 more source

Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins.

Proceedings of the National Academy of Sciences of the United States of America, 1986
K. Kohno, T. Uchida, H. Ohkubo, S. Nakanishi, T. Nakanishi, T. Fukui, E. Ohtsuka, M. Ikehara, Y. Okada   +8 more
semanticscholar   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source