Results 191 to 200 of about 775,502 (352)

The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.

Proceedings of the National Academy of Sciences of the United States of America, 1982
A. Korman, C. Auffray, A. Schamboeck, J. Strominger   +3 more
semanticscholar   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

Structural basis underlying the autoinhibition of the formin FHOD1 and its phosphorylation-dependent activation. [PDF]

J Biol Chem
Syaban MFR, Shalihah SM, Kage Y, Sulistomo HW, Takeya R.   +4 more
europepmc   +1 more source

Complete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: close homology to the serine antiproteases.

Proceedings of the National Academy of Sciences of the United States of America, 1986
I. Flink, T. Bailey, T. A. Gustafson, B. Markham, E. Morkin   +4 more
semanticscholar   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Immunogenicity risk assessment of peptide-related impurities identified in generic teriparatide products. [PDF]

Front Immunol
Mattei AE, Roberts BJ, Lelias S, Miah S, Howard KE, Weaver JL, Verthelyi D, Pang ES, Edwards K, De Groot AS.   +9 more
europepmc   +1 more source

Association of amino acid sequence in the PKR‐eIF2 phosphorylation homology domain and response to interferon therapy

Hepatology, 2000
K. Chayama, F. Suzuki, A. Tsubota, M. Kobayashi, Y. Arase, S. Saitoh, Yoshiyuki Suzuki, N. Murashima, K. Ikeda, N. Takahashi, M. Kinoshita, H. Kumada   +11 more
semanticscholar   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein and its homology to histocompatibility antigens.

Proceedings of the National Academy of Sciences of the United States of America, 1988
T. Araki, F. Gejyo, K. Takagaki, H. Haupt, H. Schwick, W. Bürgi, T. Marti, J. Schaller, E. Rickli, R. Brossmer   +9 more
semanticscholar   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source