Results 41 to 50 of about 500,817 (209)

Structure and function prediction of human homologue hABH5 of _E. coli_ ALKB5 using in silico approach [PDF]

, 2011
Newly discovered human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Little is known about the structure and function of hABH5, one of the members of this superfamily.
Ambarish Sharan Vidyarthi, Saibal Das, shankaracharya shankaracharya, shankaracharya shankaracharya   +3 more
core   +5 more sources

Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]

, 2007
The potent immunomodulatory, anti-inflammatory and procoagulant properties of the protein no. 4 secreted from the rat seminal vesicle epithelium (SV-IV) have been previously found to be modulated by a supramolecular monomer-trimer ...
Ambrosone, Bairoch, Bornberg-Bauer, Bourhis, Cai, Caporale, Cheng, Coeytaux, Csizmók, Doszatányi, Dosztányi, Dunker, Dunker, Dyson, D’Ambrosio, Esposito, Ferron, Gaboriaud, Galzitskaya, Galzitskaya, Galzitskaya, Garbuzynskiy, Harris, Hirose, Ialenti, Kandala, Kyte, Li, Lin, Linding, Linding, Liu, Lupas, MacCallum, McDonald, Metafora, Metafora, Miele, Murzin, Obradovic, Obradovic, Ostrowski, Pan, Prilusky, Quevillon-Cheruel, Radivojac, Ragone, Romero, Romero, Rüping, Shimizu, Shimizu, Sickmeier, Stiuso, Stiuso, Tompa, Tufano, Uversky, Uversky, Vucetic, Ward, Weathers, Weathers, Wolf, Wootton, Wright, Yang   +66 more
core   +3 more sources

Structural differences between human proteins and aero- and microbial allergens define allergenicity. [PDF]

PLoS ONE, 2012
The current paradigm suggests that structural homology of allergenic proteins to microbial (particularly helminths) or human proteins underlie their allergenic nature. To examine systematically the structural relationships among allergens and proteins of
Helton da Costa Santiago, Sasisekhar Bennuru, José M C Ribeiro, Thomas B Nutman   +3 more
doaj   +1 more source

Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce' gene, the structural gene for cAMP phosphodiesterase [PDF]

, 1986
We have isolated and sequenced cDNA clones representing portions of the polyadenylylated transcripts of the dunce+ gene. These define an open reading frame of 1086 bases and some of the 5'- and 3'-untranslated regions of the transcripts.
Chen, Chun-Nan, Davis, Ronald L., Denome, Sylvia   +2 more
core  

Cloning and Expression Analysis of Clock Genes During Ovarian Development and Maturation of Tongue Sole (Cynoglossus semilaevis)

Progress in Fishery Sciences
Clock genes play a pivotal role in the rhythm maturation of bony fish ovaries. To explore the role of clock genes in the rhythmic ovarian development and maturation of tongue sole (Cynoglossus semilaevis), we used real-time fluorescent quantitative PCR ...
Kewen YAN, Xiaodong MA, Bao SHI, Hanliang CHENG, Chongnü WANG, Xinyu ZHAO   +5 more
doaj   +1 more source

Analysis of Conserved, Computationally Predicted Epitope Regions for VP5 and VP7 Across three Orbiviruses

Bioinformatics and Biology Insights, 2018
Orbiviruses are double-stranded RNA viruses that have profound economic and veterinary significance, 3 of the most important being African horse sickness virus (AHSV), bluetongue virus (BTV), and epizootic hemorrhagic disease virus (EHDV).
Bonnie L Russell, Nishal Parbhoo, Samantha Gildenhuys   +2 more
doaj   +1 more source

Computational Evaluation of B Cell Epitope of 37 kDa Outer Membrane Protein H (OmpH) Pasteurella multocida Type B from Nusa Tenggara Timur (NTT), Indonesia [PDF]

The Iranian Journal of Veterinary Science and Technology
HS is still a frequently reported endemic disease, with outbreaks in Indonesia. HS vaccines distributed in Indonesia exhibit various limitations. This study computationally evaluated the B-cell epitope of the 37-kDa OmpH derived from the amino acid ...
Firdausy Maulana, Didik Handijatno
doaj   +1 more source

Novel Archaeal DNA Polymerase B from Domas Hot Spring West Java [PDF]

, 2015
Nine novel archaeal DNA polymerase genes from Domas Hot Spring, West Java have been cloned directly through the natural sample.
Akhmaloka, A., Hertadi, Rukman, Nurbaiti, Santi, Suharti, S., Warganegara, Fida Madayanti   +4 more
core  

Pairwise alignment incorporating dipeptide covariation

, 2005
Motivation: Standard algorithms for pairwise protein sequence alignment make the simplifying assumption that amino acid substitutions at neighboring sites are uncorrelated.
Altschul, Altschul, Altschul, Altschul, Bailey, Bishop, Brenner, Cline, Crooks, DOOLITTLE, Frith, Fukami-Kobayashi, G. E. Crooks, Goldman, Gonnet, Henikoff, Henikoff, Jung, Karplus, Lin, Muller, Murzin, Park, Pearson, R. E. Green, RODIONOV, S. E. Brenner, Sander, Smith, Thorne, Thorne, Thorne, Topham, Weiss, Zachariah   +34 more
core   +1 more source

Genetic variation in NSP4 of type 1 porcine reproductive and respiratory syndrome virus in China

BMC Veterinary Research
Background Porcine reproductive and respiratory syndrome virus (PRRSV) is characterized by a high mutation rate. Although research has largely focused on PRRSV-2, the detection rate of PRRSV-1 in China is increasing.
Huiyang Sha, Xiaolin Lan, Zhiyu Yang, Chen Lv, Hang Zhang, Qin Luo, Yajie Zheng, Gan Li, Weili Kong, Liangzong Huang, Jun Ma, Mengmeng Zhao   +11 more
doaj   +1 more source