Results 51 to 60 of about 775,502 (352)

Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3. [PDF]

, 1992
We have previously defined ie3 as a coding region located downstream of the ie1 gene which gives rise to a 2.75-kb immediate-early (IE) transcript. Here we describe the structural organization of the ie3 gene, the amino acid sequence of the gene product,
Bühler, Bernhard, Keil, Günther M., Koszinowski, Ulrich H., Messerle, Martin   +3 more
core   +1 more source

Mediterranean Fin Whales (Balaenoptera physalus) Threatened by Dolphin MorbilliVirus [PDF]

, 2015
During 2011-2013, dolphin morbillivirus was molecularly identified in 4 stranded fin whales from the Mediterranean Sea. Nucleoprotein, phosphoprotein, and hemagglutinin gene sequences of the identified strain were highly homologous with those of a ...
BEFFAGNA, GIORGIA, Casalone, Cristina, CENTELLEGHE, CINZIA, Cocumelli, Cristiano, Denurra, Daniele, Di Francesco, Cristina Esmeralda, Di Guardo, Giovanni, MAZZARIOL, SANDRO, Pautasso, Alessandra, Pintore, Antonio, Povinelli, Michele, Terracciano, Giuliana   +11 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Architecture of coatomer: Molecular characterization of delta-COP and protein interactions within the complex [PDF]

, 1996
Copyright © 2011 by The Rockefeller University Press.Coatomer is a cytosolic protein complex that forms the coat of COP I-coated transport vesicles.
Auerbach, S, Faulstich, D, Harter, C, Lottspeich, F, Orci, L, Ravazzola, M, Stenbeck, G, Tschochner, H, Wegchingel, S, Wieland, FT   +9 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Computational Evaluation of B Cell Epitope of 37 kDa Outer Membrane Protein H (OmpH) Pasteurella multocida Type B from Nusa Tenggara Timur (NTT), Indonesia [PDF]

The Iranian Journal of Veterinary Science and Technology
HS is still a frequently reported endemic disease, with outbreaks in Indonesia. HS vaccines distributed in Indonesia exhibit various limitations. This study computationally evaluated the B-cell epitope of the 37-kDa OmpH derived from the amino acid ...
Firdausy Maulana, Didik Handijatno
doaj   +1 more source

Novel Archaeal DNA Polymerase B from Domas Hot Spring West Java [PDF]

, 2015
Nine novel archaeal DNA polymerase genes from Domas Hot Spring, West Java have been cloned directly through the natural sample.
Akhmaloka, A., Hertadi, Rukman, Nurbaiti, Santi, Suharti, S., Warganegara, Fida Madayanti   +4 more
core  

Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]

, 2007
The potent immunomodulatory, anti-inflammatory and procoagulant properties of the protein no. 4 secreted from the rat seminal vesicle epithelium (SV-IV) have been previously found to be modulated by a supramolecular monomer-trimer ...
Ambrosone, Bairoch, Bornberg-Bauer, Bourhis, Cai, Caporale, Cheng, Coeytaux, Csizmók, Doszatányi, Dosztányi, Dunker, Dunker, Dyson, D’Ambrosio, Esposito, Ferron, Gaboriaud, Galzitskaya, Galzitskaya, Galzitskaya, Garbuzynskiy, Harris, Hirose, Ialenti, Kandala, Kyte, Li, Lin, Linding, Linding, Liu, Lupas, MacCallum, McDonald, Metafora, Metafora, Miele, Murzin, Obradovic, Obradovic, Ostrowski, Pan, Prilusky, Quevillon-Cheruel, Radivojac, Ragone, Romero, Romero, Rüping, Shimizu, Shimizu, Sickmeier, Stiuso, Stiuso, Tompa, Tufano, Uversky, Uversky, Vucetic, Ward, Weathers, Weathers, Wolf, Wootton, Wright, Yang   +66 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structure and function prediction of human homologue hABH5 of _E. coli_ ALKB5 using in silico approach [PDF]

, 2011
Newly discovered human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Little is known about the structure and function of hABH5, one of the members of this superfamily.
Ambarish Sharan Vidyarthi, Mr. Shankaracharya, Saibal Das   +2 more
core   +5 more sources