Results 81 to 90 of about 136,209 (296)

Sequential decision making with adaptive utility [PDF]

open access: yes, 2008
Decision making with adaptive utility provides a generalisation to classical Bayesian decision theory, allowing the creation of a normative theory for decision selection when preferences are initially uncertain.
Houlding, Brett
core  

A Survey of Non-Learning-Based Abstractions for Sequential Decision-Making

open access: yesIEEE Access
ion techniques play a crucial role in enabling agents to make decisions more effectively by simplifying complex problems. This survey provides a comprehensive literature overview of non-learned abstraction construction methods and explores how these ...
Robin Schmocker, Alexander Dockhorn
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A personalized decision aid for prostate cancer shared decision making

open access: yes, 2021
A shared decision-making model is preferred for engaging prostate cancer patients in treatment decisions. However, the process of assessing an individual's preferences and values is challenging and not formalized.
Morton, Gerard   +9 more
core   +1 more source

Non-linear model-based sequential decision-making in agriculture

open access: yesEnvironmental Research Communications
Agricultural decision-making faces a dual challenge: sustaining high yields to meet global food security needs while reducing the environmental impacts of input use, including fertilizer losses (e.g., nutrient runoff and leaching) and other agrochemical ...
Sakshi Arya, Wentao Lin
doaj   +1 more source

The effect of incentive structure on search in the secretary problem [PDF]

open access: yesJudgment and Decision Making, 2020
We tested the effectiveness of performance-based incentive structures using three incentive structures --- commission base, best only and flat fee --- and two levels of context --- no context and house-selling --- in an experiment in which participants ...
Yu-Chin Hsiao, Simon Kemp
doaj  

Algorithms for Fairness in Sequential Decision Making

open access: yes, 2019
It has recently been shown that if feedback effects of decisions are ignored, then imposing fairness constraints such as demographic parity or equality of opportunity can actually exacerbate unfairness. We propose to address this challenge by modeling feedback effects as Markov decision processes (MDPs). First, we propose analogs of fairness properties
Min Wen, Osbert Bastani, Ufuk Topcu
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Sequential decision problems, dependently typed solutions

open access: yes, 2013
We propose a dependently typed formalization for a simple class of sequential decision problems. For this class of problems, we im- plement a generic version of Bellman's backwards induction algorithm [2] and a machine checkable proof that the proposed ...
Botta, Nicola   +2 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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