Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum. [PDF]
, 2016 Malaria is caused by an obligate intracellular protozoan parasite that replicates within and destroys erythrocytes. Asexual blood stages of the causative agent of the most virulent form of human malaria, Plasmodium falciparum, can be cultivated ...
Bell, Donald +7 more
core +5 more sources
First isolation of West Nile virus from a dromedary camel [PDF]
, 2016 published_or_final_versio
Chan, KH +11 more
core +1 more source
Identification of a Plasmodium falciparum phospholipid transfer protein. [PDF]
, 2013 Infection of erythrocytes by the human malaria parasite Plasmodium falciparum results in dramatic modifications to the host cell, including changes to its antigenic and transport properties and the de novo formation of membranous compartments within the ...
Blackman, Michael J +5 more
core +2 more sources
Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro [PDF]
, 2013 Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Alves, Maria Julia Manso +2 more
core +2 more sources
transcriptional profiling of [PDF]
, 2004 Background: Both host and pathogen factors contribute to disease outcome in Plasmodium falciparum infection. The feasibility of studying the P. falciparum in vivo transcriptome to understand parasite transcriptional response while it resides in the human
Ali Sultan +10 more
core +3 more sources
Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
, 2018 Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core +2 more sources
Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection [PDF]
, 2011 Background The Plasmodium falciparum merozoite surface protein Pf38 is targeted by antibodies of malaria immune adults and has been shown to be under balancing (immune) selection in a Gambian parasite population, indicating potential as a malaria vaccine
Alyssa E Barry +4 more
core +3 more sources
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor. [PDF]
, 2021 Malaria parasite egress from host erythrocytes (RBCs) is regulated by discharge of a parasite serine protease called SUB1 into the parasitophorous vacuole (PV). There, SUB1 activates a PV-resident cysteine protease called SERA6, enabling host RBC rupture
Blackman, Michael J +10 more
core +2 more sources
Sex-partitioning of the Plasmodium falciparum stage V gametocyte proteome provides insight into falciparum-specific cell biology [PDF]
, 2014 One of the critical gaps in malaria transmission biology and surveillance is our lack of knowledge about Plasmodium falciparum gametocyte biology, especially sexual dimorphic development and how sex ratios that may influence transmission from the human ...
Dinglasan, R. R. +10 more
core +1 more source
Large mammal recovery in the wake of human population decline
Journal of Applied Ecology, Volume 63, Issue 5, May 2026.Human depopulation, particularly in rural areas, has contributed to the recovery of some large mammal populations. While recovery is generally good news for conservation, it can also lead to human‐wildlife conflict. We present several avenues to maximize coexistence in the face of further rural depopulation in other places. Read the free Plain Language
Alex J. Jensen +4 more
wiley +1 more source