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Phasing Serial Crystallography Data
2018The development of serial femtosecond crystallography (SFX) at X-ray free electron lasers (X-ray FELs) allows for the use of tiny protein crystals down to just a few unit cells along an edge, measured at physiological temperatures, and with a time resolution far better than can be achieved with synchrotrons or electron microscopes.
Richard A. Kirian +2 more
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Serial Millisecond Crystallography of Membrane Proteins
2016Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) is a powerful method to determine high-resolution structures of pharmaceutically relevant membrane proteins. Recently, the technology has been adapted to carry out serial millisecond crystallography (SMX) at synchrotron sources, where beamtime is more abundant.
Kathrin, Jaeger +5 more
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Serial Synchrotron X-Ray Crystallography (SSX)
2017Prompted by methodological advances in measurements with X-ray free electron lasers, it was realized in the last two years that traditional (or conventional) methods for data collection from crystals of macromolecular specimens can be complemented by synchrotron measurements on microcrystals that would individually not suffice for a complete data set ...
Kay, Diederichs, Meitian, Wang
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Microcrystal segmentation for serial crystallography
2023Presentation given during the "Leveraging open data from PaN facilities for machine learning" at Soleil synchrotron during 17–18 oct. 2023. https://indico.synchrotron-soleil.fr/event/67/
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Use of fixed targets for serial crystallography
In serial crystallography, large numbers of microcrystals are sequentially delivered to an X-ray beam and a diffraction pattern is obtained from each crystal. This serial approach was developed primarily for X-ray Free Electron Lasers (XFELs) where crystals are destroyed by the beam but is increasingly used in synchrotron experiments.Sofia, Jaho +4 more
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Chemical crystallography by serial femtosecond X-ray diffraction
Nature, 2022Elyse A Schriber +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2020
Eugenio de la Mora +2 more
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Eugenio de la Mora +2 more
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Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser
Nature, 2014Christopher Kupitz +2 more
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Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography
Cell, 2015Haitao Zhang +2 more
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The hit-and-return system enables efficient time-resolved serial synchrotron crystallography
Nature Methods, 2018Eike C Schulz +2 more
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