L-serine metabolic regulation and host respiratory homeostasis [PDF]
Frontiers in Cellular and Infection MicrobiologyL-Serine, a non-essential amino acid (NEAA), can be obtained through diet or in situ synthesis. Functionally, L-serine not only serves as the precursor of other amino acids, lipids, and nucleotides, but also participates in the folate/methionine cycle ...
Pan Li +5 more
doaj +2 more sources
Age-Dependent Changes in Taurine, Serine, and Methionine Release in the Frontal Cortex of Awake Freely-Moving Rats: A Microdialysis Study [PDF]
LifeBrain function declines because of aging and several metabolites change their concentration. However, this decrease may be a consequence or a driver of aging.
Cristina Cueto-Ureña +3 more
doaj +2 more sources
Characterization of Bioactivity and Antimicrobial Metabolite Production in Bacteria Antagonistic to Plant and Foodborne Molds [PDF]
, 2021 Biocontrol agents show promise in mitigating the drawbacks of synthetic chemicals. This study investigates potential biocontrol bacteria isolated from disease suppressive composts to reduce Fusarium dry rot on potato tubers, and to gain insight into the ...
Ramlawi, Serine
core +2 more sources
An atlas of substrate specificities for the human serine/threonine kinome
Nature, 2023 Protein phosphorylation is one of the most widespread post-translational modifications in biology^ 1 , 2 . With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of serine and threonine phosphorylation have so far been identified, and ...
Jared L. Johnson +39 more
semanticscholar +1 more source
Insulin-regulated serine and lipid metabolism drive peripheral neuropathy
Nature, 2023 Serine deficiency can increase small fibre neuropathy in wild-type mice and serine replacement in diabetic mice alleviates diabetic neuropathy, directly linking amino acid metabolism to peripheral nerve disorders.
Michal K. Handzlik +21 more
semanticscholar +1 more source
Frontiers in Plant Science, 2021 The metabolism of an organism is closely related to both its internal and external environments. Metabolites can act as signal molecules that regulate the functions of genes and proteins, reflecting the status of these environments. This review discusses
Mutsumi Watanabe +3 more
doaj +1 more source
Contesting futures of Artificial Intelligence (AI) in healthcare: formal expectations meet informal anticipations [PDF]
, 2023 Artificial Intelligence (AI) technologies are expected to play an essential role in future healthcare systems for saving resources, improving treatment quality and enhancing patient safety.
Kannelønning, Mari Serine
core +1 more source
Mapping the ACE2 binding site on the SARS-CoV-2 spike protein S1: molecular recognition pattern [PDF]
Proceedings of the Estonian Academy of Sciences, 2020 Coronavirus SARS-CoV-2 enters the host cell via binding with the angiotensin-converting enzyme 2 (ACE2), and here we used computational modelling to study the molecular recognition pattern of this interaction.
Aleksei Kuznetsov, Jaak Järv
doaj +1 more source
Nature Communications, 2021 Many tumour cells show dependence on exogenous serine and dietary serine and glycine starvation can inhibit the growth of these cancers and extend survival in mice.
Mylène Tajan +22 more
semanticscholar +1 more source
Navigating uncertainties of introducing artificial intelligence (AI) in healthcare: The role of a Norwegian network of professionals [PDF]
, 2023 Artificial Intelligence (AI) technologies are expected to solve pressing challenges in healthcare services world- wide. However, the current state of introducing AI is characterised by several issues complicating and delaying their deployments.
Kannelønning, Mari Serine
core +1 more source