Results 1 to 10 of about 1,014,425 (418)

SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

open access: yesFrontiers in Oncology, 2022
Recent research has demonstrated the diverse relationship between tumour metabolism and the tumour microenvironment (TME), for example, abnormal serine metabolism.
Weiyu Kong   +6 more
doaj   +1 more source

The effect of a methyl group on structure and function: Serine vs. threonine glycosylation and phosphorylation

open access: yesFrontiers in Molecular Biosciences, 2023
A variety of glycan structures cover the surface of all cells and are involved in myriad biological processes, including but not limited to, cell adhesion and communication, protein quality control, signal transduction and metabolism, while also being ...
Joseph J. Barchi, Caitlin N. Strain
doaj   +1 more source

Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine

open access: yesFrontiers in Oncology, 2022
The impact of asparaginases on plasma asparagine and glutamine is well established. However, the effect of asparaginases, particularly those derived from Erwinia chrysanthemi (also called crisantaspase), on circulating levels of other amino acids is ...
Dominique Bollino   +13 more
doaj   +1 more source

Serine Metabolism in Health and Disease and as a Conditionally Essential Amino Acid

open access: yesNutrients, 2022
L-serine plays an essential role in a broad range of cellular functions including protein synthesis, neurotransmission, and folate and methionine cycles and synthesis of sphingolipids, phospholipids, and sulphur containing amino acids.
M. Holeček
semanticscholar   +1 more source

Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation

open access: yesFrontiers in Nutrition, 2023
Phosphatidylethanolamine is the major inner-membrane lipid in the plasma and mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine and diacylglycerol (DAG) by the CDP-ethanolamine pathway and from phosphatidylserine by
Michaela St Germain   +2 more
doaj   +1 more source

#BlackCharactersMatter: If I’m Trying to Teach for Social Justice, Why Do All the Black Men and Boys on my Syllabus Die?

open access: yesRadical Teacher, 2020
In this essay combining first-person narrative and scholarly literature, a classroom teacher examines the ways in which, despite having a self-professed goal of teaching for social justice, her syllabus centers, upholds, and normalize default whiteness ...
Andrea Serine Avery
doaj   +1 more source

Bio-Insecticide of Thymus vulgaris and Ocimum basilicum Extract from Cell Suspensions and Their Inhibitory Effect against Serine, Cysteine, and Metalloproteinases of the Red Palm Weevil (Rhynchophorus ferrugineus)

open access: yesInsects, 2021
The current study was designed to investigate the insecticide role of volatile constituents produced from cell suspensions of T. vulgaris and O. basilicum against R. ferrugineus. Constituents were extracted from cell suspension after 40 days.
Hossam Moustafa Darrag   +2 more
doaj   +1 more source

Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance. [PDF]

open access: yes, 2020
Recent evidence suggests that enhanced protease-mediated inflammation may promote insulin resistance and result in diabetes. This study tested the hypothesis that serine protease plays a pivotal role in type 2 diabetes, and inhibition of serine protease ...
Chen, Jaw-Wen   +7 more
core   +1 more source

Mapping the ACE2 binding site on the SARS-CoV-2 spike protein S1: molecular recognition pattern [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2020
Coronavirus SARS-CoV-2 enters the host cell via binding with the angiotensin-converting enzyme 2 (ACE2), and here we used computational modelling to study the molecular recognition pattern of this interaction.
Aleksei Kuznetsov, Jaak Järv
doaj   +1 more source

The serine transporter SdaC prevents cell lysis upon glucose depletion in Escherichia coli

open access: yesMicrobiologyOpen, 2020
The amino acid serine plays diverse metabolic roles, yet bacteria actively degrade exogenously provided serine via deamination to pyruvate. Serine deamination is thought to be a detoxification mechanism due to the ability of serine to inhibit several ...
Michelle A. Kriner   +1 more
doaj   +1 more source

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