Results 1 to 10 of about 623,620 (248)

Roles of serine in neurodegenerative diseases

EXCLI Journal : Experimental and Clinical Sciences, 2023
Jia-Meng Li, Shuang-Qing Zhang
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Convenient Synthesis of Thiohydantoins, Imidazole-2-thiones and Imidazo[2,1-b]thiazol-4-iums from Polymer-Supported α-Acylamino Ketones

Molecules, 2018
The preparation of 5-methylene-thiohydantoins using solid-phase synthesis is reported in this paper. After sulfonylation of immobilized Ser (t-Bu)-OH with 4-nitrobenzenesulfonyl chloride followed by alkylation with various bromoketones, the 4-Nos group ...
Petra Králová, Michal Maloň, Hiroyuki Koshino, Miroslav Soural   +3 more
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In Vitro Antiproliferative Effect of the Whole Extract and Serine Protease of Lumbricus terrestris on the MCF-7 Cell Line

Medical Journal of Babylon
Background: Earthworms are a type of invertebrate that has been used for medicinal purposes for many millennia. Earthworm extracts have been the subject of numerous attempts to explain their anticancer properties.
Ayman Abdel Salam Qassem, Farha A. Ali Shafi, Nebrass Faleh   +2 more
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Protein and amino acid profile of Ruditapes decussatus and Ruditapes philippinarum from Çanakkale Strait, Türkiye

Oceanological and Hydrobiological Studies
Protein content was lowest in April 2018 and highest in May 2018 for Ruditapes decussatus (Linnaeus 1758), and was lowest in September 2017 and highest in December 2017 for Ruditapes philippinarum (Adams, Reeve 1850).
Bilgen Pervin Vural, Acarlı Sefa, Berber Selçuk, Celik Pinar, Kale Semih   +4 more
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Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks

Frontiers in Oncology
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by metabolic plasticity that fuels growth, therapy resistance, and immune evasion. Among its reprogrammed pathways, serine and lipid metabolism play central roles.
Dongxin Jiang, Chuheng Wang, Yao Zhao, Yunqian Li   +3 more
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Chemoselective O-acylation of hydroxyamino acids and amino alcohols under acidic reaction conditions: History, scope and applications

Beilstein Journal of Organic Chemistry, 2015
Amino acids, whether natural, semisynthetic or synthetic, are among the most important and useful chiral building blocks available for organic chemical synthesis.
Tor E. Kristensen
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Cellular Redox Imbalance and Neurochemical Effect in Cognitive-Deficient Old Rats

Behavioral Sciences, 2018
The purpose of the present study is to access the linkage between dysregulation of glutamatergic neurotransmission, oxidative metabolism, and serine signaling in age-related cognitive decline.
Maria Elena González-Fraguela, Lisette Blanco-Lezcano, Caridad Ivette Fernandez-Verdecia, Teresa Serrano Sanchez, Maria de los A. Robinson Agramonte, Lidia Leonor Cardellá Rosales   +5 more
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A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

eLife, 2019
In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples.
Fuad Mohammad, Rachel Green, Allen R Buskirk   +2 more
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Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome

Frontiers in Immunology
IntroductionA group of SARS-CoV-2 infected individuals present lingering symptoms, defined as long COVID (LC), that may last months or years post the onset of acute disease.
Suguru Saito, Shima Shahbaz, Xian Luo, Mohammed Osman, Desiree Redmond, Jan Willem Cohen Tervaert, Liang Li, Liang Li, Shokrollah Elahi, Shokrollah Elahi   +9 more
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Association Between Serine Concentration and Coronary Heart Disease: A Case–Control Study

International Journal of General Medicine
Fangfang Fan,1,2,* Zhe Liang,1,2,* Zhihao Liu,1 Pengfei Sun,1 Lihua Hu,1 Jia Jia,1,2 Yan Zhang,1,2 Jianping Li1,2 1Department of Cardiology, Peking University First Hospital, Beijing, People’s Republic of China; 2Institute of Cardiovascular ...
Fan F, Liang Z, Liu Z, Sun P, Hu L, Jia J, Zhang Y, Li J   +7 more
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