Results 1 to 10 of about 660,366 (297)
Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks [PDF]
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by metabolic plasticity that fuels growth, therapy resistance, and immune evasion. Among its reprogrammed pathways, serine and lipid metabolism play central roles.
Dongxin Jiang +3 more
doaj +2 more sources
The Regulatory Role of Quorum Sensing-Mediated Amino Acid Metabolism in Biofilm Formation and Motility of Hafnia alvei H4 [PDF]
The spoilage phenotype of microorganisms is a key mechanism leading to food spoilage, but how their metabolic environment affects the spoilage phenotype remains unclear. This study utilized metabolomics and spoilage phenotype analysis to reveal metabolic
Congyang Yan +5 more
doaj +2 more sources
Effects of D-Serine and MK-801 on Neuropathic Pain and Functional Recovery in a Rat Model of Spinal Cord Injury [PDF]
Objective Neuropathic pain is a common secondary complication of spinal cord injury (SCI). N-methyl-D-aspartate (NMDA) receptor activation is critical for hypersensitivity in neuropathic pain.
Dongwoo Yu +8 more
doaj +1 more source
QUANTUM-CHEMICAL SIMULATION OF THE INTERACTION OF AMINO ACIDS WITH CALCIUM CARBONATE
This article presents the results of quantum chemical modeling of the interaction of the CO32-anion with a number of proteinogenic amino acids to identify the most energetically advantageous system and further compare with the results of a laboratory ...
D. M. Remizov +4 more
doaj +1 more source
: This study was designed to evaluate the effect of dietary Ser on performance, egg quality, serum indices, and ileal mucosal immunity in laying hens fed low crude protein (LCP), essential amino acids (EAA) balanced diets.
Jian-min Zhou +5 more
doaj +1 more source
In this essay combining first-person narrative and scholarly literature, a classroom teacher examines the ways in which, despite having a self-professed goal of teaching for social justice, her syllabus centers, upholds, and normalize default whiteness ...
Andrea Serine Avery
doaj +1 more source
Phosphorylation of Calpastatin Negatively Regulates the Activity of Calpain
Tenderness is an important characteristic of meat quality. Calpastatin and calpain play important roles in meat tenderization. However, it is not clear how phosphorylation affects the regulation of calpastatin on μ-calpain and, consequently, meat ...
Yuqiang Bai +6 more
doaj +1 more source
Genomic investigation of emerging zoonotic pathogen Shewanella xiamenensis
Objective: Shewanella xiamenensis is an emerging zoonotic pathogen commonly found in aquatic ecosystem. Clustered regularly interspaced short palindromic repeats (CRISPR) and (CRISPR)-associated gene systems act as adaptive immune system of prokaryotes ...
Jui-Hsing Wang +2 more
doaj +1 more source
Serine-Selective Bioconjugation
The first general method for the rapid, chemoselective, and modular functionalization of serine residues in native polypeptides is reported. Using a reagent platform based on P(V) oxidation state, this redox-economic approach can be used to append nearly any kind of cargo onto serine generating a stable, benign, and hydrophilic phosphorothioate linkage.
Vantourout, Julien C +16 more
openaire +6 more sources
Gut microbiota and their secreted metabolites have an influence on the initiation and progression of colon cancer. Probiotics are extensively perceived as a potential microbiota-modulation strategy to promote the health of the host, while the ...
Fuqiang Xu +7 more
doaj +1 more source

