Results 251 to 260 of about 652,471 (299)

Synthetic Mimics of Serine Proteases via Covalent Imprinting of Photo-Protected Template Molecules for Aryl Amide Hydrolysis. [PDF]

Chemistry
Barik R, Zhao Y.
europepmc   +1 more source

Mechanistic insights into alpha-synuclein neuronal toxicity: Misfolding, serine phoshorylation, and interactions with Rab GTPases.

, 2012
Guowei Yin
openalex   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities. [PDF]

Chembiochem
Glinka FL, Mehnert K, Koch L, Schmöker O, Steil L, Hentschker C, Völker U, Johannesen TB, Böttcher D, Lammers M, Bröker BM, Bornscheuer UT.   +11 more
europepmc   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

<i>In Silico</i> Structural Analysis of the Grapevine Serine Protease VviSBT4.19 Involved in Defense against <i>P. viticola</i>. [PDF]

J Agric Food Chem
Rodrigues FEP, Ferreira SGF, Paiva-Silva C, Figueiredo A, Santos RB, Machuqueiro M.   +5 more
europepmc   +1 more source

Delivery of lipid nanoparticles containing small interfering RNA targeting transmembrane serine protease 4 in a human gastric cancer model using nude mice. [PDF]

Sci Rep
Tazawa H, Ishida Y, Suzuki T, Shimizu Y, Tashiro H.   +4 more
europepmc   +1 more source

One-carbon metabolism in cancer: moonlighting functions of metabolic enzymes and anti-tumor therapy. [PDF]

Cancer Metastasis Rev
Cao X, Guo Y, Guo Z, Liu Y, Dou Y, Xue L.   +5 more
europepmc   +1 more source

Advances in selective targeting of serine hydrolases: A targeted covalent approach against hCES2A mitigates irinotecan toxicity <i>in vivo</i>. [PDF]

Acta Pharm Sin B
De Vita E.
europepmc   +1 more source