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Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB[Figure presented]

open access: yesDiscovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB[Figure presented]
Nonenzymatic D-isomerization of aspartic acid in proteins has been observed in lesions associated with age-related diseases, including cataracts and Alzheimer's disease. Given that D-isomerization of Asp disrupts the physiological conformation of proteins, it has been postulated that D-isomerization of Asp in proteins is a key factor in the ...
openaire  

Lysosomal protease-mediated APP degradation is pH-dependent, mutation-sensitive, and facilitates tau proteolysis. [PDF]

open access: yesMol Neurodegener Adv
Ackley C   +8 more
europepmc   +1 more source

Targeting the proline-glycine-proline-protease feed-forward loop attenuates primary graft dysfunction after lung transplantation. [PDF]

open access: yesFront Immunol
Goda Y   +14 more
europepmc   +1 more source

Impact of cellular proteases on the function of antiviral antibodies. [PDF]

open access: yesJ Virol
Krzypow M   +3 more
europepmc   +1 more source

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