On nonemptiness of Newton strata in the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$ [PDF]
We build upon our previous work to study the Newton stratification on the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$. Our main result gives an explicit classification of all nonempty Newton strata associated to a Frobenius-conjugacy class satisfying certain conditions on the Newton polygon.
arxiv
Crinumin, a novel substitute of chymotrypsin, may control pancreatic insufficiency and inflammation: Purification and characterization [PDF]
Crinumin, a glycosylated serine protease with chymotrypsin like catalytic specificity was purified from a medicinally important plant _Crinum asiaticum_ of family _Amaryllidaceae_.
Chandan Singh+3 more
core +2 more sources
Serine proteases and serine protease inhibitors in testicular physiology: the plasminogen activation system [PDF]
The testis is an organ in which a series of radical remodeling events occurs during development and in adult life. These events likely rely on a sophisticated network of proteases and complementary inhibitors, including the plasminogen activation system. This review summarizes our current knowledge on the testicular occurrence and expression pattern of
openaire +3 more sources
Rapid adaptive responses were evident from reciprocal host-plant switches on performance, digestive physiology and relative gene expression of gut serine proteases in larvae of crucifer pest P.
Pawan Kumar+5 more
doaj +1 more source
Serine Proteases: an Ab Initio Molecular Dynamics Study [PDF]
In serine proteases (SP's), the H-bond between His-57 and Asp-102, and that between Gly-193 and the transition state intermediate play a crucial role for enzymatic function. To shed light on the nature of these interactions, we have carried out ab initio molecular dynamics simulations on complexes representing adducts between the reaction intermediate ...
arxiv
Polyprotein processing: cis and trans proteolytic activities of Sesbania mosaic virus serine protease [PDF]
Sesbania mosaic virus (SeMV) polyprotein was shown to undergo proteolytic processing when expressed in E. coli. Mutational analysis of the proposed catalytic triad residues (H181, D216, and S284) present in the N-terminal serine protease domain of the ...
Lokesh, G.L.+2 more
core +1 more source
Cleavage of endogenous gamma ENaC and elevated abundance of alpha ENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells [PDF]
Using human H441 airway epithelial cells cultured at air–liquid interface (ALI), we have uniquely correlated the functional response to apical fluid volume expansion with the abundance and cleavage of endogenous α- and γENaC proteins in the apical ...
Baines, DL, Selvanathar, IA, Tan, CD
core +2 more sources
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak+2 more
wiley +1 more source
Model for crankshaft motion of protein backbone in nonspecific binding site of serine proteases [PDF]
The consequences of recent experimental finding that hydrogen bonds of the anti-parallel $\beta $-sheet in nonspecific binding site of serine proteases become significantly shorter and stronger synchronously with the catalytic act are examined. We investigate the effect of the transformation of an ordinary hydrogen bond into a low-barrier one on the ...
arxiv
Differential in vitro and in vivo effect of barley cysteine and serine protease inhibitors on phytopathogenic microorganisms [PDF]
Protease inhibitors from plants have been involved in defence mechanisms against pests and pathogens. Phytocystatins and trypsin/α-amylase inhibitors are two of the best characterized protease inhibitor families in plants.
Cambra Marin, Ines+5 more
core +2 more sources