IUBMB Life, 2009 AbstractOver one third of all known proteolytic enzymes are serine proteases. Among these, the trypsins underwent the most predominant genetic expansion yielding the enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis, and immunity.
openaire +3 more sources
Preliminary investigations on the serine and aspartic protease inhibitors from Nothopegia beddomei
Ceylon Journal of Science, 2019 Aqueous stem bark extract of Nothopegia beddomei was assayed for serine and aspartic protease inhibitors by using trypsin and pepsin as the target enzymes, respectively. Crude bark extract was dialyzed and subjected to inhibition assays.
M.G.K.P. Dayarathne, Sanath Rajapakse
doaj +1 more source
Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease. [PDF]
PLoS ONE, 2014 Fusobacterium nucleatum is an oral anaerobe associated with periodontal disease, adverse pregnancy outcomes and colorectal carcinoma. A serine endopeptidase of 61-65 kDa capable of damaging host tissue and of inactivating immune effectors was detected ...
Lior Doron +6 more
doaj +1 more source
The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]
, 2010 The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page +43 more
core +1 more source
Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA [PDF]
, 2009 HGF (hepatocyte growth factor) is a pleiotropic cytokine homologous to the serine protease zymogen plasminogen that requires canonical proteolytic cleavage to gain functional activity.
Andrew M. Schumacher +47 more
core +3 more sources
Engineering novel complement activity into a pulmonary surfactant protein [PDF]
, 2010 Complement neutralizes invading pathogens, stimulates inflammatory and adaptive immune responses, and targets non- or altered-self structures for clearance.
Anthony H. Keeble +38 more
core +2 more sources
Molecules, 2011 Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of serine protease from kesinai (Streblus asper) leaves.
Md. Zaidul Islam Sarker +3 more
doaj +1 more source
Exploring the Antibiotic Potential of a Serine Protease from <i>Solanum trilobatum</i> Against <i>Staphylococcus aureus</i> Biofilms. [PDF]
Infect Dis RepRadhakrishnan M +5 more
europepmc +3 more sources
A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]
, 2005 Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA +5 more
core +2 more sources
Serine protease from Indian Cobra venom: its anticoagulant property and effect on human fibrinogen [PDF]
, 2020 An unusual low molecular weight serine protease (NnP28) has been purified from Indian Cobra (Naja naja) venom from the western region of the Indian sub-continent.
Divya Kumar +6 more
core +1 more source