Results 201 to 210 of about 422,331 (334)

Serine Protease HTRA1 [PDF]

, 2020
openaire   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

Advanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim, Seoyoon Song, Ali Zamat, Paul S. Pelkowski, Shivashankar Subramanian, Melissa Cadena, Sydney Fabrega, Meredith Brienen, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +10 more
wiley   +1 more source

Mechanistic and Kinetic Insights into the Acylation Reaction of Hepatitis C Virus NS3/NS4A Serine Protease with NS4B/5A Substrate. [PDF]

Biomolecules
Martínez-González JÁ, Salazar-Sanchez N, Larriva-Hormigos M, Martínez R, González M.   +4 more
europepmc   +1 more source

Gain-of-function study reveals the pleiotropic roles of serine protease HtrA inBorrelia burgdorferi [PDF]

Kai Zhang, Ching Wooen Sze, Hang Zhao, Jun Liu, Chunhao Li   +4 more
openalex   +1 more source

Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain. [PDF]

, 2006
Santiago Cal, Juan R. Peinado, Maria Llamazares Prada, Vı́ctor Quesada, Ángela Moncada-Pazos, Cecilia Garabaya, Carlos López-Otı́n   +6 more
openalex   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

The cell-surface serine protease prostasin is lost during cervical squamous cell carcinogenesis. [PDF]

Hum Cell
Lundgren JG, Flynn MG, List K.
europepmc   +1 more source

Molecular cloning of seprase: a serine integral membrane protease from human melanoma

, 1997
Leslie A. Goldstein, Giulio Ghersi, Mayra L. Piñeiro-Sánchez, Monica Salamone, Yunyun Yeh, Denise Flessate, Wen‐Tien Chen   +6 more
openalex   +1 more source

Midgut serine proteases and alternative host plant utilization in Pieris brassicae L. [PDF]

, 2015
Rakesh Kumar, Usha Bhardwaj, Pawan Kumar, Sudeshna Mazumdar–Leighton   +3 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source