Results 21 to 30 of about 358,313 (362)
Interdependence of kallikrein-related peptidases in proteolytic networks [PDF]
, 2010 Human kallikrein-related peptidases (KLKs) are 15 homologous serine proteases involved in several (patho)physiological processes, including cancer. Secreted as precursors, they are activated upon proteolytic release of a short propeptide. We searched for
Debela +21 more
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IUBMB Life, 2009 AbstractOver one third of all known proteolytic enzymes are serine proteases. Among these, the trypsins underwent the most predominant genetic expansion yielding the enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis, and immunity.
openaire +4 more sources
Preliminary investigations on the serine and aspartic protease inhibitors from Nothopegia beddomei
Ceylon Journal of Science, 2019 Aqueous stem bark extract of Nothopegia beddomei was assayed for serine and aspartic protease inhibitors by using trypsin and pepsin as the target enzymes, respectively. Crude bark extract was dialyzed and subjected to inhibition assays.
M.G.K.P. Dayarathne, Sanath Rajapakse
doaj +1 more source
Molecules, 2011 Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of serine protease from kesinai (Streblus asper) leaves.
Md. Zaidul Islam Sarker +3 more
doaj +1 more source
Protean proteases: At the cutting edge of lung diseases [PDF]
, 2017 Proteases were traditionally viewed as mere protein-degrading enzymes with a very restricted spectrum of substrates. A major expansion in protease research has uncovered a variety of novel substrates, and it is now evident that proteases are critical ...
Borensztajn, Keren S. +11 more
core +3 more sources
Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. [PDF]
PLoS ONE, 2011 Serine proteases are major components of viper venom and target various stages of the blood coagulation system in victims and prey. A better understanding of the diversity of serine proteases and other enzymes present in snake venom will help to ...
Sakthivel Vaiyapuri +4 more
doaj +1 more source
TNF-α and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes [PDF]
, 2019 BACKGROUND: Serine proteases have important roles in skin barrier function and desquamation, and the aberrant expression or the dysfunction of serine proteases is associated with the pathogenesis of skin diseases.
Hirai, Yoji +8 more
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Serine Proteases of Parasitic Helminths
The Korean Journal of Parasitology, 2015 Serine proteases form one of the most important families of enzymes and perform significant functions in a broad range of biological processes, such as intra- and extracellular protein metabolism, digestion, blood coagulation, regulation of development, and fertilization.
Mingyuan Liu +6 more
openaire +3 more sources
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
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In vitro characterization of jellyfish venom fibrin(ogen)olytic enzymes from Nemopilema nomurai
Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Background Because jellyfish are capable of provoking envenomation in humans, they are considered hazardous organisms. Although the effects of their toxins are a matter of concern, information on the venom components, biological activity and pathological
Seong Kyeong Bae +8 more
doaj +1 more source