Results 31 to 40 of about 422,331 (334)

SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms. [PDF]

open access: yesPLoS ONE, 2013
Serine protease inhibitors act as modulators of serine proteases, playing important roles in protecting animal toxin peptides from degradation. However, all known serine protease inhibitors discovered thus far from animal venom belong to the Kunitz-type ...
Zongyun Chen   +7 more
doaj   +1 more source

T-SP1: a novel serine protease-like protein predominantly expressed in testis [PDF]

open access: yes, 2008
Here, we describe a novel member in the group of membrane-anchored chymotrypsin (S1)-like serine proteases, namely testis serine protease 1 (T-SP1), as it is principally expressed in testis tissue.
Geissler, Claudia   +6 more
core   +1 more source

Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S]

open access: yesJournal of Lipid Research, 2020
Individuals with Netherton syndrome (NTS) have increased serine protease activity, which strongly impacts the barrier function of the skin epidermis and leads to skin inflammation. Here, we investigated how serine protease activity in NTS correlates with
Jeroen van Smeden   +9 more
doaj   +1 more source

‘Heat-Treatment Aqueous Two Phase System’ for Purification of Serine Protease from Kesinai (Streblus asper) Leaves

open access: yesMolecules, 2011
A ‘Heat treatment aqueous two phase system’ was employed for the first time to purify serine protease from kesinai (Streblus asper) leaves. In this study, introduction of heat treatment procedure in serine protease purification was investigated.
Shuhaimi Mustafa   +2 more
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

open access: yes, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G   +5 more
core   +3 more sources

A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity

open access: yesJournal of Pharmacological Sciences, 2016
Emerging evidence has suggested that aldosterone has direct deleterious effects on the kidney independently of its hemodynamic effects. However, the detailed mechanisms of these direct effects remain to be elucidated.
Yutaka Kakizoe   +13 more
doaj   +1 more source

The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases [PDF]

open access: yes, 2002
The protein SpoIVB plays a key role in signaling in the sigma (K) checkpoint of Bacillus subtilis. This regulatory mechanism coordinates late gene expression during development in this organism and we have recently shown SpoIVB to be a serine peptidase ...
Brannigan, J A, Cutting, S M, Hoa, N T
core   +2 more sources

The GB virus C (GBV-C) NS3 serine protease inhibits HIV-1 replication in a CD4+ T lymphocyte cell line without decreasing HIV receptor expression. [PDF]

open access: yesPLoS ONE, 2012
INTRODUCTION: Persistent infection with GBV-C (GB Virus C), a non-pathogenic virus related to hepatitis C virus (HCV), prolongs survival in HIV infection. Two GBV-C proteins, NS5A and E2, have been shown previously to inhibit HIV replication in vitro. We
Sarah L George   +3 more
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

open access: yes, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H.   +4 more
core   +1 more source

Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties

open access: yesMarine Drugs, 2010
Extracts of the Floridian marine cyanobacterium Lyngbya cf. confervoides were found to deter feeding by reef fish and sea urchins (Diadema antillarum).
Susan Matthew   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy