Results 31 to 40 of about 415,034 (343)

Comparative evolutionary histories of fungal proteases reveal gene gains in the mycoparasitic and nematode-parasitic fungus Clonostachys rosea

open access: yesBMC Evolutionary Biology, 2018
Background The ascomycete fungus Clonostachys rosea (order Hypocreales) can control several important plant diseases caused by plant pathogenic fungi and nematodes. Subtilisin-like serine proteases are considered to play an important role in pathogenesis
Mudassir Iqbal   +5 more
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

open access: yes, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H.   +4 more
core   +1 more source

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa

open access: yesVeterinary Research, 2011
Several alphaherpesviruses breach the basement membrane during mucosal invasion. In the present study, the role of proteases in this process was examined.
Glorieux Sarah   +4 more
doaj   +1 more source

Cleavage of endogenous gamma ENaC and elevated abundance of alpha ENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells [PDF]

open access: yes, 2011
Using human H441 airway epithelial cells cultured at air–liquid interface (ALI), we have uniquely correlated the functional response to apical fluid volume expansion with the abundance and cleavage of endogenous α- and γENaC proteins in the apical ...
Baines, DL, Selvanathar, IA, Tan, CD
core   +2 more sources

Cloning and characterization of Bombyx mandarina serine protease-like protein

open access: yes浙江大学学报. 农业与生命科学版, 2014
The complementary deoxyribonucleic acid (cDNA) of Bombyx mandarina serine protease-like protein gene was cloned by reverse transcription-polymerase chain reaction (RT-PCR).
Zhang Yongliang, Wu Anquan, Zhao Jinhui
doaj   +1 more source

SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms. [PDF]

open access: yesPLoS ONE, 2013
Serine protease inhibitors act as modulators of serine proteases, playing important roles in protecting animal toxin peptides from degradation. However, all known serine protease inhibitors discovered thus far from animal venom belong to the Kunitz-type ...
Zongyun Chen   +7 more
doaj   +1 more source

Reelin Is a Serine Protease of the Extracellular Matrix [PDF]

open access: yesJournal of Biological Chemistry, 2002
Reelin is an extracellular matrix protein that plays a pivotal role in development of the central nervous system. Reelin is also expressed in the adult brain, notably in the cerebral cortex, where it might play a role in synaptic plasticity. The mechanism of action of reelin at the molecular level has been the subject of several hypotheses.
Maria Giulia Farace   +7 more
openaire   +8 more sources

Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S]

open access: yesJournal of Lipid Research, 2020
Individuals with Netherton syndrome (NTS) have increased serine protease activity, which strongly impacts the barrier function of the skin epidermis and leads to skin inflammation. Here, we investigated how serine protease activity in NTS correlates with
Jeroen van Smeden   +9 more
doaj   +1 more source

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]

open access: yes, 2005
Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA   +5 more
core   +2 more sources

Serine proteases, serine protease inhibitors, and protease-activated receptors: Roles in synaptic function and behavior [PDF]

open access: yesBrain Research, 2011
Serine proteases, serine protease inhibitors, and protease-activated receptors have been intensively investigated in the periphery and their roles in a wide range of processes-coagulation, inflammation, and digestion, for example-have been well characterized (see Coughlin, 2000; Macfarlane et al., 2001; Molinari et al., 2003; Wang et al., 2008; Di Cera,
Antoine G. Almonte, J. David Sweatt
openaire   +3 more sources

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