Results 171 to 180 of about 59,691 (267)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia (FM) and no‐pain controls completed questionnaire‐based ratings of chronic pain, childhood trauma, anxiety and depression. Brief touch stimuli were then administered, including slow brushing at the C‐tactile optimal velocity of 3 cm/s, deep oscillating pressure with a compression sleeve, roboticized ...
Benedetta Albinni   +7 more
wiley   +1 more source

Exploring non-autonomous protein homeostasis driven by glutamatergic neurons. [PDF]

open access: yesMicroPubl Biol
Hruby AJ   +8 more
europepmc   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

Contribution of the Serotonin 5‐HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Psilocin, the active metabolite of psilocybin, ameliorated social avoidance behavior in mice exposed to chronic social defeat stress when administered after, but not before, stress exposure via serotonin 5‐HT2A receptor activation. These findings suggest that psilocin exerts therapeutic, but not preventive, effects on stress‐induced social behavioral ...
Daisuke Ibi   +10 more
wiley   +1 more source

The Monoamine-Glutamate Continuum of Depression: A Neurobiological Framework for Precision Psychiatry. [PDF]

open access: yesPharmaceuticals (Basel)
Carmellini P   +5 more
europepmc   +1 more source

The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Takahiko Nagamine
wiley   +1 more source

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