Results 161 to 170 of about 59,691 (267)

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

Psychiatry and Clinical Neurosciences, EarlyView.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury, Elvira Pirondini, Damien Benis, Tiffany Corbet, Gabriel Thorens, Christian Lüscher, Paul Krack   +6 more
wiley   +1 more source

Neuroimaging of the monoaminergic system in Parkinson's disease: A narrative review. [PDF]

Neuroimage Rep
Samanci Y, Tan S, Temel Y, Jahanshahi A.
europepmc   +1 more source

Intermittent low‐intensity contractions cause a dissociation between maximal motor unit firing rates and changes in torque and contractile speed

Experimental Physiology, EarlyView.
Abstract The purpose was to test: (1) whether the decline in maximal motor unit (MU) firing rate is an invariable response when maximal voluntary contraction (MVC) torque is reduced following a submaximal muscle fatiguing task; and (2) whether fatigue‐induced slowing of contractile speed and firing rate decline are co‐dependent. Ten participants (three
Alexander M. Zero, Raaj A. Dudani, Jacob Fanous, Charles L. Rice   +3 more
wiley   +1 more source

Effects of Electrical Stimulation of Raphe Magnus on Locomotion and Selected Cognitive Abilities in Rats. [PDF]

Int J Mol Sci
Ptaszek K, Jerzemowska G, Plucińska K, Świergiel AH, Zabielska-Kaczorowska MA.   +4 more
europepmc   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

The Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero, Franck Brocherie, Olivier Girard, Nathan Townsend, Chris J. McNeil, Grégoire P. Millet   +5 more
wiley   +1 more source

Optical insights into spatial precision and release heterogeneity of neuromodulatory transmission. [PDF]

iScience
Zheng WS, Gupta S, Zhang P, Zhang Y.
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Unexpected Improvement of Obsessive-Compulsive Disorder Symptoms Following the Mistaken Prescription of Clomiphene: A Novel Perspective on Hormonal Influences in OCD. [PDF]

Case Rep Psychiatry
Hosseini SH, Abbasi B, Abedian Kenari F.
europepmc   +1 more source

Psychotropic medication and the fetal brain

The Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

Integrated Metabolomic and Transcriptomic Analyses Reveal Alterations in the Serotonergic Synapse Pathway and a Robust Diagnostic Model in Ulcerative Colitis. [PDF]

Metabolites
Wang H, Wu H, Fu Y, Lv X, Li C, Jin Y, Ge W, Wu Z.   +7 more
europepmc   +1 more source