Results 181 to 190 of about 66,706 (287)

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Unraveling the Cycle: A Scoping Review Exploring the Impact of Antidepressants on the Female Reproductive Cycle. [PDF]

Cureus
Weatherly S, Garazi CD, Woldenberg E, Ravigopal T, Costin J.   +4 more
europepmc   +1 more source

Subchronic Exposure to Aripiprazole Subtly Impacts on Rodents' Sperm Quality and Fertility

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Aripiprazole, a third‐generation antidepressant/antipsychotic drug, acts on serotonergic and dopaminergic receptors and is widely prescribed for mental disorders, such as depression and schizophrenia. Studies indicate that this class of drugs can impact directly on sperm quality and fertility.
Maria Joana Nogueira de Moura, Renata Gleysiane Sousa de Felix, Aline Gabriele Gomes da Silva, Ana Beatriz Silva Angelo, Caio César Araújo dos Santos, Artemia Kelly Holanda Pereira, Michelly Fernandes de Macedo, Cibele dos Santos dos Borges   +7 more
wiley   +1 more source

Increased central serotonergic activity in patients after an acute ischemic stroke. An EEG study. [PDF]

Clin Neurophysiol Pract
Flasbeck V, Ebert A, Klostermann B, Richter D, Gold R, Krogias C, Juckel G.   +6 more
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Organization of Serotonergic Cell Populations in the Brain and Spinal Cord of the Short-Lived African Turquoise Killifish. [PDF]

Biology (Basel)
González-Llera L, Arana ÁJ, Sánchez L, Anadón R, Barreiro-Iglesias A.   +4 more
europepmc   +1 more source

Modulation of acetylcholine release by serotonergic 5-HT1A and 5-HT1B receptors : A microdialysis study in the awake rat

, 2007
Xiao Hu
openalex  

Neuroleptic Malignant Syndrome on Chronic Trifluoperazine Therapy: A Diagnostic Dilemma. [PDF]

Clin Case Rep
Baral S, Bhattarai S, Joshi KC.
europepmc   +1 more source

Drug‐Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 503-513, February 2026.
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐prolonging potential and registered related clinical outcomes.
Ola Nordqvist, Olof Björneld, Patrick Bergman, Björn Wettermark, Alisa Lincke, Marine L. Andersson, Tora Hammar   +6 more
wiley   +1 more source

Exploring the mechanism of methyl parathion and its degradation product on depression through network toxicology and molecular docking. [PDF]

Sci Rep
Cao M, Fan BB, Xu LS, Xu J, Zhang YH.
europepmc   +1 more source