Results 201 to 210 of about 59,691 (267)

Cytoplasmic TDP-43 leads to early behavioral impairments without neurodegeneration in a serotonergic neuron-specific C. elegans model. [PDF]

Sci Rep
Lacour A, Vassallu F, Romussi S, Rayes D, Igaz LM.   +4 more
europepmc   +1 more source

Neural mechanisms linking Western diet consumption and cognitive impairment: a role for the vagus nerve. [PDF]

Clin Sci (Lond)
Hayes AMR, Bashaw AG, Klug ME, Kanoski SE.   +3 more
europepmc   +1 more source

Parkinson's disease beyond motor symptoms: a review of the validity and limitations of current classification of non-motor symptoms. [PDF]

Front Psychiatry
Makhani A, Mestre TA, Abe AM.
europepmc   +1 more source

Gut Microbiota-Mediated Modulation of Intestinal Serotonin by Tea Polyphenols: Potential Mechanisms and Implications for Metabolic Health. [PDF]

Nutrients
Jiang L, Yu Y, Zheng M, Cao X, Li J.
europepmc   +1 more source

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Serotonergic therapy in epilepsy

Current Opinion in Neurology, 2021
Purpose of review The serotonergic system is implicated in multiple aspects of epilepsy, including seizure susceptibility, sudden unexpected death in epilepsy (SUDEP), and comorbid depression. Despite the complexity of serotonin's effects on various neuronal networks, ongoing research provides considerable insight into the role
Gilliam, Frank G., Hecimovic, Hrvoje, Gentry, Matthew S.   +2 more
openaire   +3 more sources

Serotonergic Genes and Suicidality

Crisis, 2001
Summary: Several lines of evidence indicate that abnormalities in the functioning of the central serotonergic system are involved in the pathogenesis of depressive illness and suicidal behavior. Studies have shown that the number of brain and platelet serotonin transporter binding sites are reduced in patients with depression and in suicide victims ...
, David Bakish, Lisheng Du
exaly   +3 more sources

Serotonergic and non‐serotonergic targets in the pharmacotherapy of visceral hypersensitivity

Neurogastroenterology & Motility, 2007
Abstract  Visceral hypersensitivity is considered a key mechanism in the pathogenesis of functional gastrointestinal (GI) disorders. Targeting visceral hypersensitivity seems an attractive approach to the development of drugs for functional GI disorders. This review summarizes current knowledge on targets for the treatment of visceral hypersensitivity,
BUENO L., DE PONTI, FABRIZIO, FRIED M., KULLAK UBLICK G. A., KWIATEK M. A., POHL D., QUIGLEY E. M. M., TACK J., TALLEY N. J.   +8 more
openaire   +3 more sources

Tetrahydroisoquinolines and the serotonergic system

Drug and Alcohol Dependence, 1979
Abstract Although its oxidation to acetate overwhelmingly predominates, acetaldehyde (ACH) formed during ethanol metabolism can be “trapped” by condensation with catecholamines (CAs) or DOPA. The condensation products, tetrahydroisoquinolines (TIQs), have been detected in the brains of mice chronically exposed to ethanol [1] and in the urine of ...
J J, Hannigan, M A, Collins
openaire   +2 more sources

Serotonergic ergoline derivatives

Bioorganic & Medicinal Chemistry Letters, 1998
Novel classes of 13- and 14-tertbutyl-ergoline derivatives were prepared, and characterised in vitro for their affinity for adrenergic, dopaminergic and serotonergic binding sites. This study particularly examines the importance of the presence and the position of the tert-butyl group in conferring either significant 5-HT1A or 5-HT2 affinity and ...
S, Mantegani, E, Brambilla, C, Caccia, G, Damiani, M G, Fornaretto, R A, McArthur, M, Varasi   +6 more
openaire   +2 more sources