Results 211 to 220 of about 59,691 (267)
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Intrahypothalamic Serotonergic Neurons
Nutritional Neuroscience, 1999Serotonin's role as a neuronal transmitter was established already forty years ago, and the anatomy and many of the functions of the major serotonergic systems have been carefully mapped. The intimate association of serotonergic mechanisms with central control of food intake has also been extensively studied.
S, Vanhatalo, S, Soinila
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Reward and the serotonergic system
Neuroscience, 2010Anhedonia, as a failure to experience rewarding stimuli, is a key characteristic of many psychiatric disorders including depression and schizophrenia. Investigations on the neurobiological correlates of reward and hedonia/anhedonia have been a growing subject of research demonstrating several neuromodulators to mediate different aspects of reward ...
G S, Kranz, S, Kasper, R, Lanzenberger
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Serotonergic targets in depression
Current Opinion in Pharmacology, 2002Serotonin reuptake inhibitors have proved to be a very effective treatment for depression and have strengthened the hypothesis that impaired 5-hydroxytryptamine (5-HT) neurotransmission may contribute to the underlying cause of depressive disorders. Extensive research has been carried out to investigate other 5-HT targets associated with the disease ...
Derek N, Middlemiss +2 more
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Serotonergic mechanisms in anxiety
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 19941. Anatomical, behavioral, neurochemical and electrophysiological evidence collectively support a role for central 5-HT in the modulation of anxiety and the anti-anxiety action of the benzodiazepines. 2. The advent of selective agonists and antagonists for 5-HT receptor subtypes (5-HT1, 5-HT2, 5-HT3) has rekindled investigation of the role of 5-HT in ...
A S, Eison, M S, Eison
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Psychiatric Clinics of North America, 1997
Since its identification in neurons of the central nervous systems (CNS), serotonin (5-HT) has been implicated in the pathophysiology of psychiatric disorders, such as schizophrenia, depression, generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD).
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Since its identification in neurons of the central nervous systems (CNS), serotonin (5-HT) has been implicated in the pathophysiology of psychiatric disorders, such as schizophrenia, depression, generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD).
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Serotonergic modulation of Yawning
Pharmacology Biochemistry and Behavior, 1979Yawning induced by intraperitoneal (IP) injection of physostigmine (0.15 mgKg-1), in infant or adult rats is potentiated by Lu 10-171 (0.5-10 mgKg-1), a selective serotonin uptake inhibiting drug, which, by itself does not induce yawning. This effect is counteracted by metergoline (5-10 mgKg-1, IP) which blocks serotonin postsynaptic receptors.
R, Urba-Holmgren +3 more
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Serotonergic mechanisms in hypertension
International Journal of Cardiology, 1993Serotonin and abnormal serotonergic activity (both central and peripheral) may play a role in pathogenesis of essential hypertension. Serotonin acts chiefly via three types of receptors namely S1, S2 and S3 serotonergic receptors. Besides being vasoactive, it has some inotropic and chronotropic properties and also affects blood rheology.
M, Chandra, N, Chandra
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Serotonergic hypothesis of sleepwalking
Medical Hypotheses, 2005Despite widespread prevalence of sleepwalking, its etiology and pathophysiology are not well understood. However, there is some evidence that sleepwalking can be precipitated by sleep-disordered breathing. A hypothesis is proposed that serotonergic system may be a link between sleep-disordered breathing and sleepwalking. Serotonergic neurons meet basic
Grzegorz Juszczak, Artur Hugo Ĺwiergiel
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2015
Abundant preclinical evidence suggests that serotonin-containing neural systems may participate in the regulation of both extrapyramidal and neuroendocrine function. In an attempt to examine these possibilities in man, patients with various neurologic disorders received drugs believed to facilitate or inhibit serotonergic function. Extrapyramidal signs
T N, Chase, I, Shoulson, A C, Carter
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Abundant preclinical evidence suggests that serotonin-containing neural systems may participate in the regulation of both extrapyramidal and neuroendocrine function. In an attempt to examine these possibilities in man, patients with various neurologic disorders received drugs believed to facilitate or inhibit serotonergic function. Extrapyramidal signs
T N, Chase, I, Shoulson, A C, Carter
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The Serotonergic System and Anxiety
NeuroMolecular Medicine, 2004The wide use of serotonin reuptake inhibitors and serotonin receptor agonists in anxiety disorders has suggested a key role for the modulatory neurotransmitter in anxiety. However, serotonin's specific role is still uncertain. This article reviews the literature concerning how and where serotonergic agents modulate anxiety.
Joshua A, Gordon, Rene, Hen
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