Results 221 to 230 of about 59,691 (267)
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The serotonergic system in fish
Journal of Chemical Neuroanatomy, 2011Neurons using serotonin (5-HT) as neurotransmitter and/or modulator have been identified in the central nervous system in representatives from all vertebrate clades, including jawless, cartilaginous and ray-finned fishes. The aim of this review is to summarize our current knowledge about the anatomical organization of the central serotonergic system in
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Serotonergic Mechanisms in Myoclonus
1979Post-hypoxic intention myoclonus is a specific myoclonic syndrome in which central serotonergic tone may be deficient. Tryptophan and 5-hydroxytryptophan administration to patients with post-hypoxic intention myoclonus increases pre-existing low levels of 5-hydroxyindoleacetic acid levels in the cerebrospinal bluid, and also suppresses myoclonus ...
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Specification and differentiation of serotonergic neurons
Stem Cell Reviews, 2006Serotonin is an important neurotransmitter with multiple functions in the whole central nervous system. Its synthesis, however, is restricted to a very limited number of cells in the brainstem raphe nuclei with a vast axonal network. These cells express markers of the serotonin lineage such as the rate-limiting enzyme in serotonin synthesis, tryptophan
Natalia, Alenina +2 more
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Novel serotonergic and non-serotonergic migraine headache therapies
Expert Opinion on Therapeutic Patents, 2001In the last four years discovery of pharmacotherapeutic treatments for migraine headaches has received much attention. Since the patent literature was last reviewed in 1997 [1], advances have been made in the understanding of mechanism and pathophysiology of migraine. Introduction of sumatriptan to the market has led to acceleration in research efforts
Abdelmalik Slassi +2 more
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Serotonergic Dysfunction in Depression
British Journal of Psychiatry, 1989Various irregularities in serotonin (5-HT) function have been postulated as causes of affective disorders. Serotonin has been related to many of the major symptoms of depression, e.g. mood, appetite, sleep, activity, and cognitive dysfunction. Interference with 5-HT synthesis or storage has been shown to induce depression in vulnerable individuals ...
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Serotonergic Mediation of Vomiting
Journal of Pediatric Gastroenterology and Nutrition, 1995Summary:In the latter part of the 20th century, significant advances have been made in the understanding of the emetic reflex. As a result, there have been major improvements in the treatment of vomiting, particularly that associated with chemo‐ and radiotherapeutic treatments for neoplastic disease.
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Morphine: Effects on serotonergic neurons and neurons in areas with a serotonergic input
European Journal of Pharmacology, 1978The hypothesis that morphine acts on the serotonergic system to produce analgesia is based on the previous observations that (1) lesions and stimulation of midbrain raphe nuclei after the threshold to nociceptive stimuli; (2) morphine alters the turnover of serotonin (5-hydroxytryptamine; 5-HT).
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PERIPHERAL SEROTONERGIC SYSTEM IN UREMIA
Thrombosis Research, 1996Several data suggest that platelet-derived serotonin (5-HT), previously classified as a trivial modulator of blood-borne cardiovascular disease (1), may play a decisive role in various pathological processes, resulting from abnormal platelet-vessel wall interactions (2).
D, Pawlak +5 more
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Serotonergic mechanisms in aggression.
Novartis Foundation symposium, 2005The serotonergic system in the CNS has complex interactions with many, if not all other neurotransmitter systems in the brain. Its localization, distribution and amazing receptor diversity makes it an appealing system for modulatory aspects in many basic behaviours, including food and water intake, sexual behaviour and aggression.
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