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Serotonin and Hallucinogens [PDF]
This brief review traces the serotonin (5-HT) hypothesis of the action of hallucinogenic drugs from the early 1950s to the present day. There is now converging evidence from biochemical, electrophysiological, and behavioral studies that the two major classes of psychedelic hallucinogens, the indoleamines (e.g., LSD) and the phenethylamines (e.g ...
Gerard J. Marek, George K. Aghajanian
openaire +3 more sources
Serotonin is a neurotransmitter that plays a crucial role in the regulation of several behavioral and cognitive functions by binding to a number of different serotonin receptors present on the cell surface.
Parijat Sarkar +5 more
doaj +1 more source
Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. [PDF]
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these ...
Barsoum, Amir +11 more
core +2 more sources
[No abstract available]
Bryan L. Roth, Atheir I. Abbas
openaire +3 more sources
Serotonin is a monoamine that could be found in plans, animals and human body. The homeostasis of serotonin is maintained by the series of interdependent processes that include synthesis, storage, transport and removal/degradation. In the human body serotonin is synthesized in two independent compartments that are separated by brain-blood barrier.
MÜCK-ŠELER, DOROTEA, PIVAC, NELA
openaire +4 more sources
Biological clocks in the duodenum and the diurnal regulation of duodenal and plasma serotonin. [PDF]
Serotonin in blood plasma is primarily synthesized in the duodenum, as brain derived serotonin does not cross the blood-brain barrier. Because serotonin in the brain and retina is synthesized under the control of a circadian clock, we sought to determine
Elizabeth Ebert-Zavos +3 more
doaj +1 more source
Serotonin system in the human placenta – the knowns and unknowns
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger widely distributed in the brain and various other organs. Its homeostasis is maintained by the coordinated activity of a variety of proteins, including enzymes of ...
Maja Perić +4 more
doaj +1 more source
The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation [PDF]
Pulmonary arterial hypertension (PAH) is a devastating vasculopathy that predominates in women and has been associated with dysregulated estrogen and serotonin signaling. Overexpression of the serotonin transporter (SERT+) in mice results in an estrogen-
Anagnostopoulou, Aikaterini +9 more
core +1 more source
Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki +7 more
doaj +1 more source
Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta +6 more
core +4 more sources

