Results 31 to 40 of about 595,872 (286)
Telotristat ethyl reverses myxomatous changes in mice mitral valves
Frontiers in Cardiovascular Medicine, 2022 RationaleMyxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse.
Xinmei Wang +3 more
doaj +1 more source
Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]
, 2014 In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core +1 more source
Modulation of tryptophan/serotonin pathway by probiotic supplementation in human immunodeficiency virus-positive patients: preliminary results of a new study approach [PDF]
, 2017 Background: To date, no data are available regarding the effects of probiotics on the pathway of tryptophan/serotonin metabolism among human immunodeficiency virus (HIV) 1–infected individuals.
Cavallari, Eugenio Nelson +14 more
core +9 more sources
Serotonin: beyond menopause [PDF]
Romanian Journal of Medical Practice, 2016 Serotonin is a brain neurotransmitter, a local gut-produced pro-kinetic agent and a platelets-released monoamine with haemostasis role. We focus on revealing the serotonin interferences with menopause mainly related to climacteric syndrome and bone ...
Mara Carsote +5 more
doaj +1 more source
Serotonin system in the human placenta – the knowns and unknowns
Frontiers in Endocrinology, 2022 The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger widely distributed in the brain and various other organs. Its homeostasis is maintained by the coordinated activity of a variety of proteins, including enzymes of ...
Maja Perić +4 more
doaj +1 more source
Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]
, 2002 Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Allgulander C +41 more
core +1 more source
Serotonin transporter dependent modulation of food-seeking behavior.
PLoS ONE, 2020 The olfactory pathway integrates the odor information required to generate correct behavioral responses. To address how changes of serotonin signaling in two contralaterally projecting, serotonin-immunoreactive deutocerebral neurons impacts key odorant ...
Jianzheng He +4 more
doaj +1 more source
Serotonin and Hallucinogens [PDF]
Neuropsychopharmacology, 1999 This brief review traces the serotonin (5-HT) hypothesis of the action of hallucinogenic drugs from the early 1950s to the present day. There is now converging evidence from biochemical, electrophysiological, and behavioral studies that the two major classes of psychedelic hallucinogens, the indoleamines (e.g., LSD) and the phenethylamines (e.g ...
Gerard J. Marek, George K. Aghajanian
openaire +3 more sources
Serotonin signaling through the 5-HT1B receptor and NADPH oxidase 1 in pulmonary arterial hypertension [PDF]
, 2017 Objective: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesise that in PASMCs, serotonin induces
Harvey, Adam P. +5 more
core +2 more sources
Nature Communications, 2023 Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki +7 more
doaj +1 more source