Results 41 to 50 of about 234,379 (321)
Organization of Monosynaptic Inputs to the Serotonin and Dopamine Neuromodulatory Systems
Cell Reports, 2014 Serotonin and dopamine are major neuromodulators. Here, we used a modified rabies virus to identify monosynaptic inputs to serotonin neurons in the dorsal and median raphe (DR and MR).
Sachie K. Ogawa +4 more
doaj +1 more source
The effects of glycogen synthase kinase-3beta in serotonin neurons. [PDF]
PLoS ONE, 2012 Glycogen synthase kinase-3 (GSK3) is a constitutively active protein kinase in brain. Increasing evidence has shown that GSK3 acts as a modulator in the serotonin neurotransmission system, including direct interaction with serotonin 1B (5-HT1B) receptors
Wenjun Zhou +9 more
doaj +1 more source
Serotonin: an overlooked regulator of endocytosis and endosomal sorting?
Biology Open, 2022 Serotonin is a neurotransmitter and a hormone that is typically associated with regulating our mood. However, the serotonin transporter and receptors are expressed throughout the body, highlighting the much broader, systemic role of serotonin in ...
Gregory Redpath, Nikita Deo
doaj +1 more source
Regulation of serotonin production by specific microbes from piglet gut
Journal of Animal Science and Biotechnology, 2023 Background Serotonin is an important signaling molecule that regulates secretory and sensory functions in the gut. Gut microbiota has been demonstrated to affect serotonin synthesis in rodent models.
Ziyu Liu +9 more
doaj +1 more source
Journal of Neurochemistry, 2006 AbstractIn recent years, there has been increasing evidence that serotonergic neurotransmission modulates a wide variety of experimentally induced seizures. Generally, agents that elevate extracellular serotonin (5‐HT) levels, such as 5‐hydroxytryptophan and serotonin reuptake blockers, inhibit both focal and generalized seizures, although exceptions ...
Pál Riba +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
Entity-based Claim Representation Improves Fact-Checking of Medical Content in Tweets [PDF]
arXiv, 2022 False medical information on social media poses harm to people's health. While the need for biomedical fact-checking has been recognized in recent years, user-generated medical content has received comparably little attention. At the same time, models for other text genres might not be reusable, because the claims they have been trained with are ...
arxiv
Arthritis Care &Research, EarlyView.Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson +11 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co‐morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Background: The off-target effects linezolid have the potential to cause serotonin syndrome when given in conjunction with serotonergic agents. Despite package insert labeling as a contraindication, several postmarketing studies have demonstrated a low ...
Xuping Yan +5 more
doaj +1 more source