Results 61 to 70 of about 595,872 (286)

Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis

open access: yesNutrients, 2016
The serotonergic system forms a diffuse network within the central nervous system and plays a significant role in the regulation of mood and cognition.
T. Jenkins   +3 more
semanticscholar   +1 more source

Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice

open access: yesScientific Reports, 2020
Several studies have reported that the host-microbe interactions in the gut modulate the host serotonin or 5-hydroxytryptamine (5-HT) system. Here, we evaluated the effects of Akkermansia muciniphila and its extracellular vesicles (EVs) on genes ...
Rezvan Yaghoubfar   +11 more
semanticscholar   +1 more source

Regulation of serotonin production by specific microbes from piglet gut

open access: yesJournal of Animal Science and Biotechnology, 2023
Background Serotonin is an important signaling molecule that regulates secretory and sensory functions in the gut. Gut microbiota has been demonstrated to affect serotonin synthesis in rodent models.
Ziyu Liu   +9 more
doaj   +1 more source

Female genital disorder as adverse symptom of lamotrigine treatment - A serotoninergic effect? [PDF]

open access: yes, 1998
The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake.
Amann, Benedikt   +2 more
core   +1 more source

Serotonergic agents and linezolid: Impact of exposure to more than one agent concomitantly on risk of adverse effects

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: The off-target effects linezolid have the potential to cause serotonin syndrome when given in conjunction with serotonergic agents. Despite package insert labeling as a contraindication, several postmarketing studies have demonstrated a low ...
Xuping Yan   +5 more
doaj   +1 more source

Serotonin and epilepsy [PDF]

open access: yesJournal of Neurochemistry, 2006
AbstractIn recent years, there has been increasing evidence that serotonergic neurotransmission modulates a wide variety of experimentally induced seizures. Generally, agents that elevate extracellular serotonin (5‐HT) levels, such as 5‐hydroxytryptophan and serotonin reuptake blockers, inhibit both focal and generalized seizures, although exceptions ...
Pál Riba   +3 more
openaire   +3 more sources

The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series)

open access: yesPulmonary Circulation, 2018
Increased synthesis of serotonin and/or activity of serotonin in pulmonary arteries has been implicated in the pathobiology of pulmonary arterial hypertension (PAH).
Margaret (Mandy) R. MacLean
doaj   +1 more source

Milnacipran affects mouse impulsive, aggressive, and depressive-like behaviors in a distinct dose-dependent manner [PDF]

open access: yes, 2017
Serotonin/noradrenaline reuptake inhibitors (SNRIs) are widely used for the treatment for major depressive disorder, but these drugs induce several side effects including increased aggression and impulsivity, which are risk factors for substance abuse ...
Ohmura, Yu   +3 more
core   +2 more sources

Oral Branched-Chain Amino Acid Supplements That Reduce Brain Serotonin During Exercise in Rats Also Lower Brain Catecholamines [PDF]

open access: yes, 2013
Exercise raises brain serotonin release and is postulated to cause fatigue in athletes; ingestion of branched-chain amino acids (BCAA), by competitively inhibiting tryptophan transport into brain, lowers brain tryptophan uptake and serotonin synthesis ...
Choi, Sujean   +3 more
core   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

open access: yes, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P   +8 more
core   +1 more source

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