Results 71 to 80 of about 275,194 (312)

Serotonin after β-Adrenoreceptors’ Exposition: New Approaches for Personalized Data in Breast Cancer Cells [PDF]

, 2021
Serotonin is an important monoamine in the human body, playing crucial roles, such as a neurotransmitter in the central nervous system. Previously, our group reported that β-adrenergic drugs (ICI 118,551, isoprenaline, and propranolol) influence the ...
REGUENGO, HENRIQUE, Isabel Silva, Ana Salomé Correia, Henrique Reguengo, Oliveira, José Carlos, Duarte, Diana, José Carlos Oliveira, Nuno Vale, Vale, Nuno, Silva, Isabel, Diana Duarte, Correia, Ana Salomé   +11 more
core   +1 more source

Direct serotonin release in humans shapes aversive learning and inhibition

Nature Communications
The role of serotonin in human behaviour is informed by approaches which allow in vivo modification of synaptic serotonin. However, characterising the effects of increased serotonin signalling in human models of behaviour is challenging given the ...
Michael J. Colwell, Hosana Tagomori, Fei Shang, Hoi Iao Cheng, Chloe E. Wigg, Michael Browning, Philip J. Cowen, Susannah E. Murphy, Catherine J. Harmer   +8 more
doaj   +1 more source

Sleep deprivation enhances peripheral serotonin secretion to regulate the large follicle steroidogenesis of rats

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: Sleep deprivation (SD) leads to the disturbance of the estrous cycle. Serotonin, the levels of which increase with SD, has been shown to inhibit luteinizing hormone production and the receptor has been found in the follicles.
Chueh-Ko Yang, Rick Sai-Chuen Wu, Cheng-Hsuan Wu, Theodore Rong-Yei Lin, Horng-Der Tsai   +4 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Psychobiological studies showing the serotonin involvement in cognition-related behavioral performance [PDF]

, 2013
Serotonin most often acts as an inhibitory neurotransmitter which also modulates post-synaptic activity within other neurotransmitter systems. Serotonin is synthesized from the essential amino acid tryptophan in Raphe complex neurons which innervate ...
Gonzalez-Burgos, I., Feria-Velasco, A.
core   +2 more sources

Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis [PDF]

, 2014
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological ...
Hongwei Yao, Lyda, Elizabeth, Sime, Patricia J, Patricia J Sime, Michael T Sellix, Isaac K Sundar, Sundar Isaac K., Yao Hongwei, Yao, Hongwei, Sellix Michael T., Sime Patricia J., Rahman Irfan, Sundar, Isaac K, Huang, Yadi, Yadi Huang, Rahman, Irfan, Irfan Rahman, Lyda Elizabeth, Elizabeth Lyda, Huang Yadi, Sellix, Michael T   +20 more
core   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

Advanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu, Nengsheng Fu, Zhongxin Huang, Yu Mou, Ensi Ma, Xiaoshi Wang, Tian Dong, Yujun Zhang, Danqing Liu, Di Jiang, Jingya Kuang, Rui Liao, Yifeng Tao, Leida Zhang, Chengcheng Zhang   +14 more
wiley   +1 more source

Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation [PDF]

, 2008
Background:The present experiment examined the responses of peripheral modulators and indices of brain serotonin (5-HT) and dopamine (DA) function and their association with perception of effort during prolonged exercise in the heat after creatine (Cr ...
Liam Kilduff, Kilduff Liam P, Pitsiladis Yannis P, Liam P Kilduff, Kilduff, Liam P., Yannis P Pitsiladis, Pitsiladis, Y.P., Marios Hadjicharalambous, Hadjicharalambous, M., Kilduff, L., Pitsiladis, Yannis; id_orcid, Hadjicharalambous, Marios P., Hadjicharalambous Marios   +12 more
core   +1 more source

Cyproheptadine in serotonin syndrome: A retrospective study

Journal of Family Medicine and Primary Care
Objective: Serotonin syndrome (SS) is an iatrogenic life-threatening condition caused by serotonergic agents. The treatment for SS involves the administration of a serotonin antagonist (cyproheptadine).
Sanjay Prakash, Harsh Patel, Sunil Kumar, Chetsi S. Shah   +3 more
doaj   +1 more source