Results 91 to 100 of about 275,194 (312)
Serotonin and the gut microbiome: Pathways, functions, and health implications
The MicrobeSerotonin, an evolutionarily conserved molecule produced in the gut, plays a multifaceted role in host physiology. Several organs within the host can directly synthesize serotonin, yet its activity and secretion are intricately linked to the gut ...
Sarah Abubaker, Saba Miri, Riadh Hammami
doaj +1 more source
Advanced Science, EarlyView.A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
Analysis of polyamines and serotonin by mass-analyzed ion kinetic energy spectrometry [PDF]
, 1978 Mass-analyzed ion kinetic energy (MIKE) spectra were obtained for serotonin and the polyamines. The predominant reaction observed was the loss of NH3 from the protonated species.
Lloyd, Larry D.
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Angewandte Chemie, EarlyView.We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan +5 more
wiley +2 more sources
L-Dopa and Brain Serotonin System Dysfunction
Toxics, 2015 L-dopa is used to treat the motor symptoms associated with Parkinson’s disease, a neurodegenerative movement disorder characterized by a loss of dopamine neurons.
Branden J. Stansley, Bryan K. Yamamoto
doaj +1 more source
Advanced Science, EarlyView.This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source
The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine [PDF]
, 2014 Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT. Objectives:
Farideh A. Javid +5 more
core +1 more source
Rapidly Diversifying Hydrogen‐Bonded Organic Frameworks With Permanent Porosity
Angewandte Chemie, EarlyView.This article reviews diversifying hydrogen‐bonded organic frameworks (HOFs) with permanent porosity reported over the past 15 years, based on the molecular structures of their constituent tectons. Furthermore, several distinctive aspects and concepts are described, such as permanent porosity, isostructural (isoreticular) HOFs, and multicomponent mixed ...
Taito Hashimoto, Ichiro Hisaki
wiley +2 more sources
Advanced Science, EarlyView.A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang +14 more
wiley +1 more source
Natural products affecting the human serotonergic system [PDF]
, 2000 No Full ...
Rogers, Kelly +2 more
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