Results 91 to 100 of about 274,362 (314)

Serotonin and Whisking [PDF]

open access: yesNeuron, 2003
Rhythmic whisker movements, called "whisking," are produced by a brainstem central pattern generator (CPG) that uses serotonin to induce periodic firing in facial motorneurons. During active touch, motor cortex could regulate whisking frequency by controlling the rate of firing of the serotonergic neurons.
openaire   +2 more sources

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

open access: yesAdvanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang   +17 more
wiley   +1 more source

Polymorphism of the tryptophan hydroxylase 2 (TPH2) gene is associated with chimpanzee neuroticism [PDF]

open access: yes, 2011
In the brain, serotonin production is controlled by tryptophan hydroxylase 2 (TPH2), a genotype. Previous studies found that mutations on the TPH2 locus in humans were associated with depression and studies of mice and studies of rhesus macaques have ...
Alexander Weiss   +17 more
core   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

open access: yesAdvanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim   +7 more
wiley   +1 more source

Validation of the Patient Health Questionnaire‐2 (PHQ‐2) in Detecting Depression Among Older Adults

open access: yesAGING MEDICINE, EarlyView.
PHQ‐2 effectively screens for geriatric depression with the optimal cut‐off of 3 points. ABSTRACT Objectives Depression screening tools like the Patient Health Questionnaire‐2 (PHQ‐2) are commonly used to detect depression. However, its performance in elderly populations has been less extensively studied compared to its broader adult use.
Francesco Salis   +6 more
wiley   +1 more source

The Molecular Evolution of the Serotonin System in Macaques (MACACA): a Detailed Survey of Four Serotonin-Related Genes

open access: yes, 2011
Serotonin, a hormone produced in the brain, has long been implicated in the regulation of critical behaviors, such as those related to aggression or impulse control. However, most research on serotonin has focused on the proximate connection to behavior,
Shattuck, Milena
core  

Pathogenic PF4/Polyanion ELISA‐Negative Antibodies in HIT

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Background Platelet factor 4‐polyanion enzyme‐linked immunosorbent assays (ELISAs) are considered highly sensitive for diagnosing heparin‐induced thrombocytopenia (HIT), such that current practice guidelines recommend use of ELISA‐negative results to exclude HIT.
Adam J. Kanack   +25 more
wiley   +1 more source

Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams   +8 more
wiley   +1 more source

Psychobiological studies showing the serotonin involvement in cognition-related behavioral performance

open access: yes, 2013
Serotonin most often acts as an inhibitory neurotransmitter which also modulates post-synaptic activity within other neurotransmitter systems. Serotonin is synthesized from the essential amino acid tryptophan in Raphe complex neurons which innervate ...
Gonzalez-Burgos, I., Feria-Velasco, A.
core   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

open access: yes, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian   +12 more
core  

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