Results 81 to 90 of about 275,194 (312)

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

The emerging role of serotonin in liver regeneration

Swiss Medical Weekly, 2012
Serotonin has a multifunctional role in many different organs serving either as a neurotransmitter in the central nervous system or a paracrine factor in the gastrointestinal tract.
George K Papadimas, Konstantinos N Tzirogiannis, Michael G Mykoniatis, Agni D Grypioti, Georgia A Manta, Georgios I Panoutsopoulos   +5 more
doaj   +1 more source

The Role of Serotonin in the Influence of Intense Locomotion on the Behavior Under Uncertainty in the Mollusk Lymnaea stagnalis

Frontiers in Physiology, 2020
The role of serotonin in the immediate and delayed influence of physical exercise on brain functions has been intensively studied in mammals. Recently, immediate effects of intense locomotion on the decision-making under uncertainty were reported in the ...
Hitoshi Aonuma, Hitoshi Aonuma, Maxim Mezheritskiy, Boris Boldyshev, Yuki Totani, Dmitry Vorontsov, Igor Zakharov, Etsuro Ito, Varvara Dyakonova   +8 more
doaj   +1 more source

Serotonin and Stress [PDF]

Neuropsychopharmacology, 1999
Forty-five years after its discovery, brain serotonin (5-HT) is still the subject of intense research aimed at understanding its role in stress adaptation. At the presynaptic level, numerous stressors increase nerve firing and extracellular 5-HT at the level of serotonergic cell bodies or nerve terminals.
Chaouloff, F., Berton, -, Mormède, Pierre   +2 more
openaire   +3 more sources

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

Advanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji, Tao Li, Guoqiang Lei, Huichun Luo, Xiuqian Guo, Jiao Xiang, Tao Shi, Weitang Liu, Yuxin Zhang, Xiaoyu Liao, Shutao Zhao, Jiayun Wu, Wangao Zhang, Wenhui Liu, Chuanglong He, Shuo Chen, Tao Wu, Ke Ma   +17 more
wiley   +1 more source

On the anxiogenic influence of serotonin [PDF]

, 2015
Despite over half a century of research on the role of serotonin in modulating anxiety, no consensus exists as to if serotonin should be regarded as acting mainly anxiety-dampening or anxiety-enhancing.
Näslund, Jakob
core   +1 more source

5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release

Scientific Reports
The neurotransmitter serotonin plays a pivotal role in mood and depression. It also acts as a vasoconstrictor within blood vessels and is the main neurotransmitter in the gastrointestinal system.
Lina Bukowski, Markus Emanuel Strøm, Jens Lindengren Andersen, Jannick Bang Maesen, Lin Tian, Steffen Sinning   +5 more
doaj   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Serotonin Depletion-Induced Maladaptive Aggression Requires the Presence of Androgens [PDF]

, 2015
The sex hormone testosterone and the neurotransmitter serotonin exert opposite effects on several aspects of behavior including territorial aggression.
Nilsson, Staffan, N\ue4slund, Jakob, Erik Studer, Andersson, Erik, Elias Eriksson, Nilsson, Staffan,, Studer, Erik,, Eriksson, Elias, Westberg, Lars, Andersson, Erik,, Lars Westberg, Westberg, Lars,, Staffan Nilsson, Jakob Näslund, Erik Andersson, Studer, Erik, Eriksson, Elias,, Näslund, Jakob, Näslund, Jakob,   +18 more
core   +1 more source

Addressing the serotonin hypothesis of depression through analyses of genetics, methylation and metabolite variations in glioma patients

Scientific Reports
Serotonin and serotonin metabolism has for decades been understood as playing a critical role in mood disorders and has more recently also been implicated in brain tumour biology.
Wendy Yi-Ying Wu, Beatrice Melin, Benny Björkblom, Rickard L. Sjöberg   +3 more
doaj   +1 more source