Results 71 to 80 of about 479,925 (360)

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Serotonin: an overlooked regulator of endocytosis and endosomal sorting?

Biology Open, 2022
Serotonin is a neurotransmitter and a hormone that is typically associated with regulating our mood. However, the serotonin transporter and receptors are expressed throughout the body, highlighting the much broader, systemic role of serotonin in ...
Gregory Redpath, Nikita Deo
doaj   +1 more source

Allergic fetal priming leads to developmental, behavioral and neurobiological changes in mice. [PDF]

, 2015
The state of the mother's immune system during pregnancy has an important role in fetal development and disruptions in the balance of this system are associated with a range of neurologic, neuropsychiatric and neurodevelopmental disorders ...
Ashwood, P, Careaga, M, Chang, C, Onore, CE, Schwartzer, JJ   +4 more
core   +2 more sources

De‐Saturation of Single‐Atom Copper Catalysts for Accelerating Propargylic Substitution Reactions

Advanced Materials, EarlyView.
De‐saturation of copper‐based single‐atom catalysts (De‐sat SACs) are realized by a KOH‐mediated Joule thermal shock strategy. Benefiting from the under‐saturation coordination environment of single‐atom Cu center, De‐sat Cu SACs exhibit remarkable catalytic activity in propargylic substitution reactions, tolerating a broad range of nucleophiles (N–, C–
Qilong Cai, Yang Meng, Chao Wu, Wenjia Qu, Qiang Wang, Tan Li, Chengyi Liu, Jinxing Chen, Huihui Lin, Qian He, Yafei Zhao, Shibo Xi, Jiong Lu   +12 more
wiley   +1 more source

Direct serotonin release in humans shapes aversive learning and inhibition

Nature Communications
The role of serotonin in human behaviour is informed by approaches which allow in vivo modification of synaptic serotonin. However, characterising the effects of increased serotonin signalling in human models of behaviour is challenging given the ...
Michael J. Colwell, Hosana Tagomori, Fei Shang, Hoi Iao Cheng, Chloe E. Wigg, Michael Browning, Philip J. Cowen, Susannah E. Murphy, Catherine J. Harmer   +8 more
doaj   +1 more source

Sleep deprivation enhances peripheral serotonin secretion to regulate the large follicle steroidogenesis of rats

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: Sleep deprivation (SD) leads to the disturbance of the estrous cycle. Serotonin, the levels of which increase with SD, has been shown to inhibit luteinizing hormone production and the receptor has been found in the follicles.
Chueh-Ko Yang, Rick Sai-Chuen Wu, Cheng-Hsuan Wu, Theodore Rong-Yei Lin, Horng-Der Tsai   +4 more
doaj   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Regulation of serotonin production by specific microbes from piglet gut

Journal of Animal Science and Biotechnology, 2023
Background Serotonin is an important signaling molecule that regulates secretory and sensory functions in the gut. Gut microbiota has been demonstrated to affect serotonin synthesis in rodent models.
Ziyu Liu, Yidan Ling, Yu Peng, Shuibing Han, Yuting Ren, Yujia Jing, Wenlu Fan, Yong Su, Chunlong Mu, Weiyun Zhu   +9 more
doaj   +1 more source

The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model [PDF]

, 2012
One challenge of squamous cell carcinoma of the head and neck (SCCHN) chemotherapy is a small percentage of tumor cells that arrest in the G0 phase of the cell cycle and are thus not affected by chemotherapy. This could be one reason for tumor recurrence
Arnoldner, Christoph, Diensthuber, Marc, Eckardt, Anne Gisela, Geißler, Christin, Hambek, Markus, Stöver, Timo, Wagenblast, Jens   +6 more
core   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source