Results 81 to 90 of about 595,872 (286)
The expanded biology of serotonin.
Annual Review of Medicine, 2009 Serotonin is perhaps best known as a neurotransmitter that modulates neural activity and a wide range of neuropsychological processes, and drugs that target serotonin receptors are used widely in psychiatry and neurology. However, most serotonin is found
Miles Berger, J. A. Gray, B. Roth
semanticscholar +1 more source
Platelet serotonin level predicts survival in amyotrophic lateral sclerosis. [PDF]
PLoS ONE, 2010 BackgroundAmyotrophic lateral sclerosis (ALS) is a life-threatening neurodegenerative disease involving upper and lower motor neurons loss. Clinical features are highly variable among patients and there are currently few known disease-modifying factors ...
Luc Dupuis +9 more
doaj +1 more source
Annals of Medicine, 2000 Serotonin is a naturally occurring vasoactive substance that has diverse cardiophysiological effects. These effects can be explained by the existence of serotonin receptor subtypes which mediate different biological actions. The vasoconstrictive actions of serotonin are mediated by 5-HT2 serotonergic receptors, and serotonin also amplifies the release ...
William H. Frishman, Pam Grewall
openaire +2 more sources
Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension [PDF]
, 2013 <p>Aims: Pulmonary arterial hypertension (PAH) occurs more frequently in women than men. Oestrogen and the oestrogen-metabolising enzyme cytochrome P450 1B1 (CYP1B1) play a role in the development of PAH.
Abenhaim +54 more
core +1 more source
L-Dopa and Brain Serotonin System Dysfunction
Toxics, 2015 L-dopa is used to treat the motor symptoms associated with Parkinson’s disease, a neurodegenerative movement disorder characterized by a loss of dopamine neurons.
Branden J. Stansley, Bryan K. Yamamoto
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Mechanical forces are important for normal gastrointestinal tract function. The enterochromaffin cells in the gastrointestinal epithelium have been proposed, but not previously shown, to be specialized sensors that convert forces into ...
Constanza Alcaino +10 more
semanticscholar +1 more source
Biochimie, 2019 The expression of serotonin (5-HT) in the retina was first reported in the sixties. The detection of vesicular monoamine transporter and serotonin receptors in several retinal cells confirm that 5-HT is playing a neuromodulatory role in this structure.
openaire +5 more sources
Circulating Tumour Necrosis Factor is highly correlated with brainstem serotonin transporter availability in humans [PDF]
, 2016 Preclinical studies demonstrate that pro-inflammatory cytokines increase serotonin transporter availability and function, leading to depressive symptoms in rodent models.
Burden, A. David +10 more
core +1 more source
The emerging role of serotonin in liver regeneration
Swiss Medical Weekly, 2012 Serotonin has a multifunctional role in many different organs serving either as a neurotransmitter in the central nervous system or a paracrine factor in the gastrointestinal tract.
George K Papadimas +5 more
doaj +1 more source
A High-Resolution In Vivo Atlas of the Human Brain's Serotonin System
Journal of Neuroscience, 2017 The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain functions and is critically involved in many neuropsychiatric disorders. Here, we present a high-resolution, multidimensional, in vivo atlas of four of the human brain's 5-HT
V. Beliveau +8 more
semanticscholar +1 more source