Results 81 to 90 of about 197,012 (211)

Serotonin, Kynurenine, and Indole Pathways of Tryptophan Metabolism in Humans in Health and Disease. [PDF]

Nutrients
Holeček M.
europepmc   +1 more source

Gynecologic conditions in the context of incarceration: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background More than 740 000 people identified as female at intake were incarcerated globally as of 2022, reflecting a 60% global increase since the year 2000, with a concomitant increase in gynecologic conditions experienced behind bars.
Meredith K. Wise, Sahana Raghunathan, Sreya Upputuri, Elana Jaffe Brotkin, Tre D. Thorne, Jamie Conklin, Andrea K. Knittel   +6 more
wiley   +1 more source

Special Issue "Serotonin in Health and Diseases". [PDF]

Int J Mol Sci
Voronezhskaya EE.
europepmc   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Real-World Assessment of Transcranial Direct Current Stimulation (tDCS) Combined with Sertraline in the Treatment of Depression in Vietnam. [PDF]

Neuropsychiatr Dis Treat
Do TX, Bui HQ, Dinh HV, Nguyen LV, Pham TT, Nguyen DT, Nguyen DT, Huynh LN, Pham TQ, Pham TN, Tran TN, Nguyen XT.   +11 more
europepmc   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

The Serotonin 1B Receptor Modulates Striatal Activity Differentially Based on Behavioral Context. [PDF]

eNeuro
Ng KH, Sharma A, Nautiyal KM.
europepmc   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Intestinal Sclerostin Deficiency Links Gut Dysbiosis to Altered Serotonin Homeostasis in Axial Spondyloarthritis. [PDF]

Inflammation
Mauro D, Bergot AS, Guggino G, Salzillo A, Forte G, Ciancio A, Rizzo A, Raimondo S, Lentini L, Gandolfo S, Kim SP, Wong C, De Marino B, Milling S, Alessandro R, Panarese I, Riddle RC, Zaiss MM, McGonagle D, Thomas R, Ciccia F.   +20 more
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source