Results 141 to 150 of about 235,344 (293)

Managing serotonin toxicity. [PDF]

CMAJ
Beamish IV, Austin E, Kent JT.
europepmc   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Prokinetic drugs that stimulate 5-HT₄-serotonin receptors in the human atrium. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Neumann J, Kirchhefer U, Hofmann B, Gergs U.   +3 more
europepmc   +1 more source

Adverse Effects of Unsaturated Organic Compounds on Kinetic States During Locomotion Uncovered by Comprehensive Analysis of Behavioral Toxicities in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT Organisms in human living spaces are surrounded by a variety of engineered substances. These chemical compounds have unexpected effects on the environment and human health. In particular, workers in industries face the risk of a health hazard caused by high‐dose or long‐term exposure to chemicals in the workplace.
Masahiro Tomioka
wiley   +1 more source

Effects of Glyphosate and Glyphosate‐Based Herbicides on the Mammalian Gut Microbiome: A Critical Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Glyphosate has long been considered to pose negligible direct risk to mammals on the grounds that its molecular target, 5‐enolpyruvylshikimate‐3‐phosphate synthase (EPSPS), of the shikimate pathway, is absent from animal cells. This rationale is inaccurate as a complete toxicological argument, because the shikimate pathway is present in some ...
Robin Mesnage
wiley   +1 more source

Neurokinin-3 receptor antagonists for vasomotor symptoms in menopause and breast cancer survivorship. [PDF]

CMAJ
Feng NL, Wilkinson AN, Delpero E, Srikanthan A.   +3 more
europepmc   +1 more source

Mental health and healthcare use during COVID‐19 among neurodivergent youth and youth with pre‐existing psychiatric disorders: A systematic review

JCPP Advances, EarlyView.
Abstract Background Neurodivergent youth and youth with pre‐existing psychiatric disorders may have faced additional challenges in navigating the demands and restrictions of the COVID‐19 pandemic. However, less is known about how mental health outcomes and psychiatric healthcare utilization differed across diagnostic groups and other youth‐related ...
Ulyana Sirotina, Bryndis Lara Bjarnadottir, Agnieszka Butwicka, Eivind Ystrom, Jaana Suvisaari, Olli Kiviruusu, Audun Valborgarson, Heiddis Bjork Valdimarsdottir, Helga Ask, Unnur Valdimarsdottir, Thorhildur Halldorsdottir   +10 more
wiley   +1 more source

Postoperative nausea and vomiting: current concepts, management strategies, and future perspectives. [PDF]

Front Pharmacol
Qiu L, Alhaskawi A, Abdo Moqbel SA, Yuan H.   +3 more
europepmc   +1 more source

GSK3 Inhibition During Annelid Head Regeneration Results in a Hyper‐Proliferative Blastema and Impaired Differentiation

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
A whole‐body regenerative annelid was treated with a GSK3 inhibitor. While posterior regeneration was mostly normal, GSK3 inhibition prevented differentiation of anterior‐specific structures and instead produced a persistent, oversized, hyper‐proliferative blastema. This suggests that GSK3 promotes anterior identity and halts proliferation during axial
James D. Nowotny, Eduardo E. Zattara, Maria Balarezo, Kevin G. Nyberg, Kenna M. Costello, Alexandra E. Bely   +5 more
wiley   +1 more source

Mechanisms of Serotonergic Modulation of Glial Cell Functions in the Recovery Period After Spinal Cord Injury. [PDF]

Cells
Nikiforova EV, Vetlugina A, Konovalova SP, Sysoev YI, Musienko PE.   +4 more
europepmc   +1 more source