Results 121 to 130 of about 235,344 (293)
Epileptic Disorders, EarlyView.Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori +4 more
wiley +1 more source
Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart
, 2017 Serotonin (5-Hydroxytryptamine, 5-HT) can elicit both vasoconstrictive and relaxant responses on rat coronary artery. The constrictive response has been well discussed, but the mechanism of relaxant response is less studied.
Chien, Ching-Chia Chang;Hsin, Ling-Wei;Su, Ming-Jai +1 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Epilepsia Open, EarlyView.Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Neurokinin 1/3 Receptor Antagonists for Vasomotor Symptoms in Women with Breast Cancer
healthbook TIMES. Oncology HematologyEndocrine therapy remains a cornerstone treatment for patients with hormone receptor-positive breast cancer. However, its benefits are often undermined by treatment-related adverse events, including vasomotor symptoms (VMS) such as hot flashes and night ...
Michael Gnant +2 more
doaj +1 more source
Serotonin 2C receptor antagonists induce fast-onset antidepressant effects
Current antidepressants must be administered for several weeks to produce therapeutic effects. We show that selective serotonin 2C (5-HT2C) antagonists exert antidepressant actions with a faster-onset (5 days) than that of current antidepressants (14 ...
Doukas, D. +8 more
core +1 more source
Influence of Risperidone and Other Serotonin-Dopamine Antagonists on Weight Gain [PDF]
, 2003 U ovom preglednom članku prikazani su rezultati nekoliko kliničkih studija u kojima je uspoređivan utjecaj pojedinih serotonin-dopaminskih antagonista na porast tjelesne težine.
Kučukalić, Abdulah +3 more
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