Results 11 to 20 of about 40,842 (165)

Sustained Exposure to 3,4-Methylenedioxymethamphetamine Induces the Augmentation of Exocytotic Serotonin Release in Rat Organotypic Raphe Slice Cultures

open access: yesJournal of Pharmacological Sciences, 2010
3,4-Methylenedioxymethamphetamine (MDMA) causes serotonin efflux via serotonin transporter. Recently, we have reported that sustained exposure to MDMA induced an augmentation of serotonin release in rat raphe serotonergic slice cultures.
Kazuki Nagayasu   +4 more
doaj   +1 more source

Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway

open access: yesCell Communication and Signaling, 2018
Background Besides its neurotransmitter and vasoconstriction functions, serotonin is an important mediator of numerous biological processes in peripheral tissues including cell proliferation, steatosis, and fibrogenesis.
Suryakant Niture   +6 more
doaj   +1 more source

Role of Biogenic Amines in Oviposition by the Diamondback Moth, Plutella xylostella L

open access: yesFrontiers in Physiology, 2020
Oviposition is an important reproductive behavior that is triggered by mating in insects, and biogenic amines might be involved in its regulation. The effects of biogenic amines on oviposition have only been studied in a few insect species, and the ...
Fan Li   +4 more
doaj   +1 more source

Azologization of serotonin 5-HT3 receptor antagonists

open access: yesBeilstein Journal of Organic Chemistry, 2019
The serotonin 5-hydroxytryptamine 3 receptor (5-HT3R) plays a unique role within the seven classes of the serotonin receptor family, as it represents the only ionotropic receptor, while the other six members are G protein-coupled receptors (GPCRs). The 5-
Karin Rustler   +3 more
doaj   +1 more source

Methiothepin Suppresses Human Ovarian Cancer Cell Growth by Repressing Mitochondrion-Mediated Metabolism and Inhibiting Angiogenesis In Vivo

open access: yesPharmaceutics, 2020
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. Despite treatment, most patients experience relapse and the 5-year survival rate of ovarian cancer is less than 50%.
Jin-Young Lee   +3 more
doaj   +1 more source

Cannabidiol Regulates Long Term Potentiation Following Status Epilepticus: Mediation by Calcium Stores and Serotonin

open access: yesFrontiers in Molecular Neuroscience, 2018
Epilepsy is a devastating disease, with cognitive and emotional consequences that are not curable. In recent years, it became apparent that cannabinoids help patients to cope with epilepsy.
Nicola Maggio   +4 more
doaj   +1 more source

A current view of serotonin transporters [version 1; referees: 3 approved]

open access: yesF1000Research, 2016
Serotonin transporters (SERTs) are largely recognized for one aspect of their function—to transport serotonin back into the presynaptic terminal after its release.
Louis J. De Felice
doaj   +1 more source

3D-QSAR modeling and pharmacophore study of serotonin 5HT-₂A receptors antagonists [PDF]

open access: yesArhiv za farmaciju, 2017
Creation of a statistically reliable 3D-QSAR (Quantitative Structure Activity Relationships) model enables definition of the structure of the pharmacophore for antagonists of serotonin 5-HT2A receptors and selection of the key molecular determinants for ...
Antonijević Mirjana   +4 more
doaj   +1 more source

Immunohistochemical Evaluation of Role of Serotonin in Pathogenesis of Psoriasis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Psoriasis is a common skin disorder characterized by erythaematosquamous papules and plaques. It is known to be associated with stressful and depressive disorders. Serotonin is a neurotransmitter that plays a role in the pathogenesis of
Sheren Fouad Younes, Ola Ahmed Bakry
doaj   +1 more source

A characterization of the Manduca sexta serotonin receptors in the context of olfactory neuromodulation.

open access: yesPLoS ONE, 2013
Neuromodulation, the alteration of individual neuron response properties, has dramatic consequences for neural network function and is a phenomenon observed across all brain regions and taxa.
Andrew M Dacks   +6 more
doaj   +1 more source

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