Results 21 to 30 of about 77,943 (311)

Methiothepin Suppresses Human Ovarian Cancer Cell Growth by Repressing Mitochondrion-Mediated Metabolism and Inhibiting Angiogenesis In Vivo

Pharmaceutics, 2020
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. Despite treatment, most patients experience relapse and the 5-year survival rate of ovarian cancer is less than 50%.
Jin-Young Lee, Changwon Yang, Whasun Lim, Gwonhwa Song   +3 more
doaj   +1 more source

Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. [PDF]

, 2015
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons of the lateral sector of the posterior hypothalamus and zona incerta.
Benedetto, Luciana, Chase, Michael H, Lagos, Patricia, López-Hill, Ximena, Monti, Jaime M, Pascovich, Claudia, Scorza, Cecilia, Torterolo, Pablo, Urbanavicius, Jessika   +8 more
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Cannabidiol Regulates Long Term Potentiation Following Status Epilepticus: Mediation by Calcium Stores and Serotonin

Frontiers in Molecular Neuroscience, 2018
Epilepsy is a devastating disease, with cognitive and emotional consequences that are not curable. In recent years, it became apparent that cannabinoids help patients to cope with epilepsy.
Nicola Maggio, Nicola Maggio, Nicola Maggio, Efrat Shavit Stein, Menahem Segal   +4 more
doaj   +1 more source

Evidence for Respiratory Neuromodulator Interdependence after Cholinergic Disruption in the Ventral Respiratory Column [PDF]

, 2015
Reverse dialysis of the muscarinic receptor antagonist, atropine (ATR, 50 mM), into the pre-Bötzinger Complex region of the ventral respiratory column (VRC) of awake and sleeping goats increases breathing frequency and serotonin (5-HT), substance P (SP),
Forster, Hubert, Hodges, Matthew, Miller, Justin Robert, Muere, Clarissa, Neumueller, Suzanne, Olesiak, Samantha, Pan, Lawrence   +6 more
core   +2 more sources

A current view of serotonin transporters [version 1; referees: 3 approved]

F1000Research, 2016
Serotonin transporters (SERTs) are largely recognized for one aspect of their function—to transport serotonin back into the presynaptic terminal after its release.
Louis J. De Felice
doaj   +1 more source

Combined Unilateral Blockade of Cholinergic, Peptidergic, And Serotonergic Receptors in The Ventral Respiratory Column Does Not Affect Breathing in Awake Or Sleeping Goats [PDF]

, 2015
Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P ...
Forster, Hubert, Hodges, Matthew, Langer, Thomas, Miller, Justin Robert, Muere, Clarissa, Neumueller, Suzanne, Olesiak, Samantha, Pan, Lawrence   +7 more
core   +2 more sources

3D-QSAR modeling and pharmacophore study of serotonin 5HT-₂A receptors antagonists [PDF]

Arhiv za farmaciju, 2017
Creation of a statistically reliable 3D-QSAR (Quantitative Structure Activity Relationships) model enables definition of the structure of the pharmacophore for antagonists of serotonin 5-HT2A receptors and selection of the key molecular determinants for ...
Antonijević Mirjana, Nikolić Katarina, Vučićević Jelica, Oljačić Slavica, Agbaba Danica   +4 more
doaj   +1 more source

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli, A Cippitelli, A Cippitelli, A Ettenberg, A Ettenberg, A Plaza-Zabala, A Sekino, A Van't Veer, AC Hansson, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AE Higley, AM Chirila, AM Polter, AM Thierry, AN Carey, Anh D Lê, AS Kreibich, AY Deutch, B Boutrel, B Lee, B Ribeiro Do Couto, B Setlow, B Wang, B Wang, B Wang, B Wang, B Wang, BB Land, BH Westerink, BL Lewis, BM Cox, BR Lee, C Cifani, C Li, CD Schmoutz, CJ Sanchez, CJ Sanchez, CK Nielsen, CL Pickens, CP Ford, CP O'Brien, CR Gerfen, D Economidou, D Epstein, D Funk, D Funk, D Highfield, D Highfield, D Highfield, D Liu, D Rodaros, D Rotllant, David A Baker, DC Glass, DEJ Redmond, DH Epstein, DJ Calu, DJ Calu, DM Buffalari, DM Buffalari, DM Buffalari, Douglas Funk, DR Gehlert, DR Staub, DS Zahm, DT George, DW Schulz, DW Self, E Krupitsky, EA Stone, EB Margolis, EJ Khantzian, EN Graf, EN Graf, EP Zorrilla, EP Zorrilla, F Chaouloff, F Cohen, F Georges, F Leri, F Sedki, F Weiss, FC Cruz, FJ White, G Aston-Jones, G de Guglielmo, G Zislis, GF Koob, GP Chrousos, GR Valdez, H Selye, H Yamada, HC Fox, HC Fox, J Jenkins, J Stewart, J Wang, JA Deutch, JA Gray, JA Simms, JC Umhau, JD Bremner, JD Bremner, JD Shepard, JE LeDoux, JE Morley, JJ Anker, JJ Anker, JK Richards, JK Seamans, JL McGaugh, JM Blacktop, JM Bossert, JM Bossert, JM Bossert, JM Fritschy, JN Cleck, John R Mantsch, JP McLaughlin, JP Schroeder, JR Glowa, JR Mantsch, JR Mantsch, JR Mantsch, JR Mantsch, JR McReynolds, JR Schank, JR Schank, JR Schank, JV Aldrich, JV Aldrich, K McFarland, K Van Pett, KJ Jackson, KL Conrad, KL Shelton, L Lu, L Lu, L Lu, L Lu, L Zhou, LA Briand, LE Kwako, LG Kirby, LK Vaughn, M Davis, M Davis, M Heilig, M Sakanaka, MA Ungless, MB Bannon, MD Cassell, ME Bouton, ME Bouton, ME Carroll, MEP Seligman, MF Dallman, MK Greenwald, ML Jobes, ML Price, MM Moran-Santa Maria, MM Moran-Santa Maria, MR Bruchas, MR Bruchas, MT Stefanik, MW Feltenstein, MW Feltenstein, MW Hale, N Capriles, N Omelchenko, N Sidhpura, NA Chen, NM Graziane, O Vranjkovic, O Vranjkovic, P Enrico, PE Sawchenko, PJ Fletcher, PM Beardsley, PM Beardsley, PS Regier, PV Piazza, PW Kalivas, PW Kalivas, PW Kalivas, PW Marinelli, R Ciccocioppo, R Haynes, R Kvetnansky, R Martin-Fardon, R Mongeau, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Takahata, RC Pierce, RC Twining, RD Weiss, RE See, RE See, RJ Smith, RM Gold, RP Vertes, RP Vertes, RP Waters, RY Moore, S Cabib, S Cohen, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Fanous, S Geisler, S Grimwood, S Shiffman, S Stopponi, S Stopponi, S Stopponi, S Tobin, S Tobin, SA Flavin, SE Back, SF Maier, SF Maier, SG Nair, SG Nair, SG Nair, SH Ahmed, SH Ahmed, SL Grella, SM Antelman, SO Eans, SR Bornstein, SR Sesack, SV Mahler, SV Mahler, T Holdstock, T Maric, TL Bale, TR Kosten, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, UE Ghitza, V Deroche, VA Redila, WA Hunt, WB Cannon, WM Meil, X Liu, X Liu, X Wang, Y Buczek, Y Figueroa-Guzman, Y Nawata, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Silberman, Y Zhao, Yavin Shaham, YW Chen, YY Ma, YY Ma, Z Sarnyai, ZJ Brown, ZJ Brown, ZX Xi   +291 more
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Immunohistochemical Evaluation of Role of Serotonin in Pathogenesis of Psoriasis [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Psoriasis is a common skin disorder characterized by erythaematosquamous papules and plaques. It is known to be associated with stressful and depressive disorders. Serotonin is a neurotransmitter that plays a role in the pathogenesis of
Sheren Fouad Younes, Ola Ahmed Bakry
doaj   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,, Buwalda, Bauke,, Jong, Jelly G. de,, Koolhaas, Jaap M.,, Ruiter, Anne J.H. de,, Vegt, Bea J. van der,   +5 more
core   +1 more source