Results 21 to 30 of about 235,344 (293)
A current view of serotonin transporters [version 1; referees: 3 approved]
F1000Research, 2016 Serotonin transporters (SERTs) are largely recognized for one aspect of their function—to transport serotonin back into the presynaptic terminal after its release.
Louis J. De Felice
doaj +1 more source
3D-QSAR modeling and pharmacophore study of serotonin 5HT-₂A receptors antagonists [PDF]
Arhiv za farmaciju, 2017 Creation of a statistically reliable 3D-QSAR (Quantitative Structure Activity Relationships) model enables definition of the structure of the pharmacophore for antagonists of serotonin 5-HT2A receptors and selection of the key molecular determinants for ...
Antonijević Mirjana +4 more
doaj +1 more source
Serotonin, how to find it... [PDF]
, 2013 Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system (CNS) of animals, including humans ...
Crespi, Francesco
core +1 more source
PLoS ONE, 2013 Neuromodulation, the alteration of individual neuron response properties, has dramatic consequences for neural network function and is a phenomenon observed across all brain regions and taxa.
Andrew M Dacks +6 more
doaj +1 more source
Immunohistochemical Evaluation of Role of Serotonin in Pathogenesis of Psoriasis [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Psoriasis is a common skin disorder characterized by erythaematosquamous papules and plaques. It is known to be associated with stressful and depressive disorders. Serotonin is a neurotransmitter that plays a role in the pathogenesis of
Sheren Fouad Younes, Ola Ahmed Bakry
doaj +1 more source
Modern approaches to drug treatment for vestibular vertigo
Неврология, нейропсихиатрия, психосоматика, 2021 In recent years, some progress has been achieved in elaborating the algorithms and standards for the treatment of many conditions accompanied by vertigo. The current possibilities of treating vestibular vertigo consist of a gradually expanding arsenal of
M. V. Zamergrad, S. V. Morozova
doaj +1 more source
5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release [PDF]
, 2014 The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT3) receptors.
Moffat, Christopher +5 more
core +1 more source
The Journal of Headache and PainBackground Cluster headache and migraine have a circadian timing of attacks and are linked to the trigeminovascular system. Recently the trigeminal ganglion was found to have a strong circadian rhythm, with the serotonin 2A receptor identified as a clock-
Chorong Han +8 more
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Serotonin-Induced Hypersensitivity via Inhibition of Catechol O-Methyltransferase Activity
Molecular Pain, 2012 The subcutaneous and systemic injection of serotonin reduces cutaneous and visceral pain thresholds and increases responses to noxious stimuli. Different subtypes of 5-hydroxytryptamine (5-HT) receptors are suggested to be associated with different types
Tsao Douglas +9 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source