Results 111 to 120 of about 244,384 (312)

Citalopram plus low-dose pipamperone versus citalopram plus placebo in patients with major depressive disorder: an 8-week, double-blind, randomized study on magnitude and timing of clinical response [PDF]

, 2011
Background: Selective serotonin reuptake inhibitors take several weeks to achieve their full antidepressant effects. Post-synaptic 5-HT_2A receptor activation is thought to be involved in this delayed therapeutic effect ...
A. F. Schatzberg, A. G. Wade, A. McConnachie, Blier, Buntinx, C. B. Nemeroff, Celada, Demyttenaere, E. Buntinx, G. M. Crawford, Gillespie, Guy, L. Haazen, Landen, T. Schlaepfer   +14 more
core   +1 more source

Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures

Annals of Neurology, EarlyView.
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick, Rup K. Sainju, Roshni Nair, Deidre N. Dragon, Eduardo Bravo, Laura Vilella, Xiaojin Li, Samden D. Lhatoo, George B. Richerson, Brian K. Gehlbach   +9 more
wiley   +1 more source

Differential modulation of feedforward inhibition reflects topographic organization in the olfactory system

Nature Communications
The nervous system flexibly processes information under different conditions. To do this, neural networks frequently rely on uniform expression of modulatory receptors by distinct classes of neurons to fine tune the computations supported by each ...
Julius Jonaitis, Mohd F. E. B. Mazri, John W. Hageter, Oliver Cook, Tyler R. Sizemore, Marryn M. Bennett, Jacob D. Ralston, Farzaan Salman, Emma J. Fletcher, Danielle E. Matheny, Johnston Renton, Keshav L. Ramachandra, Eric J. Horstick, Andrew M. Dacks   +13 more
doaj   +1 more source

mRNA expression profile of serotonin receptor subtypes and distribution of serotonergic terminations in marmoset brain

Frontiers in Neural Circuits, 2014
To better understand serotonin function in the primate brain, we examined the mRNA expression patterns of all the 13 members of the serotonin receptor (5HTR) family, by in situ hybridization and the distribution of serotonergic terminations by serotonin ...
Rammohan eShukla, Akiya eWatakabe, Tetsuo eYamamori   +2 more
doaj   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

EXPRESSION OF SEROTONIN RECEPTOR SUBTYPE 3A (5HT3A) ON RAT TRIGEMINAL SENSORY NEURONS. [PDF]

, 2021
Sukhbir Kaur, Angela Lopez-Ramirez, Taylor M. Hickman, Michael Hunter, Dayna L. Averitt   +4 more
openalex  

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

British Journal of Clinical Pharmacology, EarlyView.
Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola, Zachary N. Stowe, Marc L. Kalin, Michael D. Evans, Catherine M. Sherwin, Maged M. Costantine, D. Jeffrey Newport, James C. Ritchie, Angela K. Birnbaum   +8 more
wiley   +1 more source

From behavioral context to receptors: serotonergic modulatory pathways in the IC

Frontiers in Neural Circuits, 2012
In addition to ascending, descending, and lateral auditory projections, inputs extrinsic to the auditory system also influence neural processing in the inferior colliculus.
Laura M Hurley, Megan R Sullivan
doaj   +1 more source

Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. [PDF]

, 2004
We studied the influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. Both single and chronic administration of imipramine potently shortened immobility in naive rats during forced-swim testing.
Araki, Hiroaki, Gomita, Yutaka, Kitamura, Yoshihisa, Nagatani, Tadashi, Shibata, Kazuhiko, Takao, Katsuyuki   +5 more
core   +1 more source