Results 171 to 180 of about 125,767 (264)

Association of serotonin receptor gene polymorphisms with anorexia nervosa: a systematic review and meta-analysis. [PDF]

Eat Weight Disord
Bevilacqua A, Santini F, La Porta D, Cimino S.   +3 more
europepmc   +1 more source

In Vivo Effect of a Synthetic Amniotic Fluid on Fetal Lung and Gastrointestinal Tract: A Pre‐Clinical Rodent Model

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Amnioinfusions in anhydramnios aim to promote fetal lung development, but currently used fluids (Normal Saline [NS], Lactated Ringer's [LR]) fail to mimic the intrauterine environment and increase reactive oxygen species (ROS). We developed a synthetic amniotic fluid (Amnio‐well, AW) designed to reduce intrauterine ROS.
Braxton Forde, Stephanie Finoti, Marc Oria, Jose L. Peiro   +3 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT₄ activation in bovine lateral saphenous vein. [PDF]

Physiol Rep
Trotta RJ, Harmon DL, Klotz JL.
europepmc   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Potent and Selective Human 5-HT_2B Serotonin Receptor Antagonists: 4'-Cyano-(N)-methanocarba-adenosines by Synthetic Serendipity. [PDF]

J Med Chem
Tosh DK, Pavan M, Clark AA, Lammers J, Villano S, Marri S, Sgambellone S, Choi S, Lee J, Ivancich MS, Bock HA, Campbell RG, Lewicki SA, Levitan IM, Chen E, Liu N, Demby T, Gavrilova O, Gao ZG, Lucarini L, McCorvy JD, Jacobson KA.   +21 more
europepmc   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

Phytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli, Giovanni Roviello, Giorgia Magliocca, Emilia Esposito, Anna Pannaccione   +4 more
wiley   +1 more source

Effects of a Serotonin Receptor Peptide on Behavioral Pattern Separation in Sham- vs. Mild Traumatic Brain Injured Rats. [PDF]

Endocrinol Diabetes Metab J
Agbolou XM, Yoe CW, Cominski TP, Zimering MB.   +3 more
europepmc   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source